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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Genetic transformation of wheat mediated by Agrobacterium tumefaciens显示文摘 | Cheng M Fry J E Pang S Zhou H Hironaka C M Duncan D R Conner T W Wan Y | 1997 | Plant Physiol1997，，： | 2 |
| 3 | Effects of the phase-separated melt on crystallization behavior and morphology in short chain branched metallocene polyethylenes显示文摘 | Fu Q Chiu F C McCreight K W Guo M Tseng W W Cheng S Z Keating M Y Hsieh E T and DesLauriers P J | | 0，，： | 2 |
| 4 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，： | 1 |
| 5 | Susceptibility weighted imaging (SWI)显示文摘 | Haacke E M Xu Y Cheng Y C | 2004 | Magn Reson Med2004，52，3： | 1 |
| 6 | The effect of deposi- tion temperature on the properties of TiN diffusion barriers prepared by atomic layer chemical vapor deposition 显示文摘 | CHENG H E LEE W J HSU C M | 2005 | Thin Solid Films2005，485，： | 1 |
| 7 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，： | 1 |
| 8 | Bcl-2, Bcl-x(L) sequester BH3 domain-only mole cules preventing Bax-and Bak-mediated mitochondrial apoptosis 显示文摘 | CHENG E H WEI M C WEILER S | 2001 | Mol Cell2001，8，： | 1 |
| 9 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，1： | 1 |
| 10 | Fabrication and Assembly Scheduling in a Two-machine Flow Shop显示文摘 | Lin B M T Cheng T C E | 2002 | lIE Transactions2002，34，11： | 1 |
| 11 | Minimizing the Makespan in the 3-machine Assembly-type Flow Shop Scheduling Problem显示文摘 | Lee C Y Cheng T C E Lin B M T | 1993 | Management Science1993，39，5： | 1 |
| 12 | Does futures trading increase stock market volatility: The case of the NILLEI stock index futures markets 显示文摘 | Chang E C Cheng J W Pinegar M J | 1999 | Journal of Banking and Finance1999，23，5： | 1 |
| 13 | Pro - apoptotic Bax and Bak: a requisite gateway to mitochondrial dysfunction and death 显示文摘 | WEI M C ZONG W X CHENG E H | 2001 | Science2001，292，： | 1 |
| 14 | Coordinating a two-supplier and one-retailer supply chain with forecast updating 显示文摘 | Yang D Choi T M Xiao T Cheng T C E | 2011 | Automatica2011，47，7： | 1 |
| 15 | Ductal dil- atation and stenting for residual hepatolithiasis: a promising treat- ment strategy显示文摘 | SHEEN CHEN S M CHENG Y E CHEN F C | 1998 | Gut1998，42，5： | 1 |
| 16 | 1990, Photosynthetic characteristics of cassava(Manihot esculenta), a C3 species with ehlorenchymatous bundle sheath cell 显示文摘 | Edwards G E Sheta E Moore B D Dai Z Franceschi V R Cheng S H Lin C H Ku M S B | 1990 | Plant and Cell Physiology1990，31，8： | 1 |
| 17 | Susceptibility weighted imaging (SWI)显示文摘 | Haacke E M Xu Y B Cheng Y C N | 2004 | Magn Reson Med2004，52，3： | 1 |
| 18 | Proapoptotic BAX and BAK:a requisite gateway to mitochondrial dysfunction and death显示文摘 | WEI M C ZONG Wei-xing CHENG E H | | 0，，5517： | 1 |
| 19 | Board composition, regulatory regime and voluntary disclosure显示文摘 | CHENG E C M COURTENAY S M | 2006 | The International Journal of Accounting2006，，41： | 1 |
| 20 | MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche显示文摘 | Cheng L C Pastrana E Tavazoie M | 2009 | Nat Neuroscienc2009，12，4： | 1 |
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