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您的检索式：作者名="Chenglan Liu"
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| 1 | Squint-mode InISAR imaging based on nonlinear least square and coordinates transform显示文摘Aiming at the interferometric inverse synthetic aperture radar(InISAR) imaging in the presence of squint,we investigate the influence of squint on the InISAR imaging. First,coupling of the squint additive phase and the target azimuth/altitude coordinates to be solved may make the solution more difficult. Second,the squint angle may lead to estimation error of the vertical coordinates and distortion of the ultimate image. Traditional InISAR imaging algorithms can not solve the above two problems effectively,so we propose a new method which combines the nonlinear least square(NLS) and coordinates transform(CT) to estimate the target coordinates,and a three-dimensional(3-D) image consistent with the real target is obtained accordingly. Simulations show that the proposed method is effective for the squint-mode InISAR imaging. | LIU ChengLan HE Feng GAO XunZhang LI Xiang SHEN RongJun | 2011 | Science China(Technological Sciences)2011，54，12： | 5 |
| 2 | Biodegradation of bensulphuron-methyl by a novel Penicillium pinophilum strain, BP-H-02 显示文摘 | PENG Xingxing HUANG Jingfei LIU Chenglan | 2012 | Journal of Hazardous Materials2012，，： | 1 |
| 3 | Novel reference range selection method in InISAR imaging显示文摘Aiming at the reference range selection for different antennas in interferometric inverse synthetic aperture radar (InISAR) systems, this paper proposes a respective focusing (RF) method. The reference ranges for echoes of different antennas are selected respectively for RF, which is different from the traditional uniform focusing (UF) with the same reference range applied to all the antennas. First, a comparison between UF and RF for InISAR signal model considering the ranging error is given. Compared with RF, UF has an advantage in overcoming the ranging error differences between different antennas. Then the influence of ranging error upon the interferometric imaging with RF is investigated particularly, and it is found that the ranging error differences between different antennas are far smaller than the wavelength, which is advantageous to imaging. By comparing the capabilities of interferometric imaging between RF and UF, it is concluded that RF is a better choice in conquering problems such as image mismatching and phase ambiguity even with ranging errors. Simulations demonstrate the validity of the proposed method. | Chenglan Liu Feng He Xunzhang Gao Xiang Li Rongjun Shen | 2012 | Journal of Systems Engineering and Electronics2012，23，4： | 0 |
| 4 | E6-induced selective translation of WNT4 and JIP2 promotes the progression of cervical cancer via a noncanonical WNT signaling pathway显示文摘mRNA translation reprogramming occurs frequently in many pathologies,including cancer and viral infection.It remains largely unknown whether viral-induced alterations in mRNA translation contribute to carcinogenesis.Most cervical cancer is caused by high-risk human papillomavirus infection,resulting in the malignant transformation of normal epithelial cells mainly via viral E6 and E7 oncoproteins.Here,we utilized polysome profiling and deep RNA sequencing to systematically evaluate E6-regulated mRNA translation in HPV18-infected cervical cancer cells.We found that silencing E6 can cause over a two-fold change in the translation efficiency of~653 mRNAs,most likely in an eIF4E-and eIF2α-independent manner.In addition,we identified that E6 can selectively upregulate the translation of WNT4,JIP1,and JIP2,resulting in the activation of the noncanonical WNT/PCP/JNK pathway to promote cell proliferation in vitro and tumor growth in vivo.Ectopic expression of WNT4/JIP2 can effectively rescue the decreased cell proliferation caused by E6 silencing,strongly suggesting that the WNT4/JIP2 pathway mediates the role of E6 in promoting cell proliferation.Thus,our results revealed a novel oncogenic mechanism of E6 via regulating the translation of mRNAs. | Lin Zhao Longlong Wang Chenglan Zhang Ze Liu Yongjun Piao Jie Yan Rong Xiang Yuanqing Yao Yi Shi | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 0 |
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