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| 1 | Perihepatic nodes detected by point-of-care ultrasound in acute hepatitis and acute-on-chronic liver disease显示文摘AIM: To study the manifestations of perihepatic lymph nodes during the episode of acute hepatitis flare by point-of-care ultrasonography.METHODS: One hundred and seventy-six patients with an episode of acute hepatitis flare(ALT value > 5 × upper normal limit) were enrolled retrospectively. Diagnosis of etiology of the acute hepatitis flare was based on chart records and serological and virological assays. The patients were categorized into two groups(viral origin and non-viral origin) and further defined into ten subgroups according to the etiologies. An ultrasonograpy was performed within 2 h to 72 h(median, 8 h). The maximum size of each noticeable lymph node was measured. Correlation between clinical parameters and nodal manifestations was analyzed RESULTS: Enlarged lymph nodes(width ≥ 5mm)were noticeable in 110(62.5%) patients, mostly in acute on chronic hepatitis B(54.5%). The viral group had a higher prevalence rate(89/110 = 80.9%) and larger nodal size(median, 7 mm) than those of the non-viral group(21/66 = 31.8%; median, 0 mm)(P < 0.001 for both). Meanwhile, there were significant differences in the nodal size between acute and chronic viral groups(P < 0.01), and between acute hepatitis A and non-hepatitis A viral groups(P < 0.001). In logistical regression analysis, the nodal width still showed strong significance in multivariate analysis(P < 0.0001) to stratify the two groups. The area under the curve of ROC was 0.805, with a sensitivity of 80.9%, a specificity of 68.2%, positive predictive value of 80.92%, negative predictive value of 68.18%, and an accuracy of 76.14%. CONCLUSION: Point-of-care ultrasonography to detect perihepatic nodal change is valuable for clarifying the etiologies in an episode of acute hepatitis flare. | I Che Feng Szu Jen Wang Ming Jen Sheu Lok-Beng Koay Ching Yih Lin Chung Han Ho Chi Shu Sun Hsing Tao Kuo | 2015 | World Journal of Gastroenterology2015，21，44： | 2 |
| 2 | Proteomic analysis of the mode of antibacterial avtion ofsilver nanoparticles显示文摘 | Chun Nam Lok Jen Fu Chiu Chi Ming Che | 2006 | J Prot Res2006，5，4： | 1 |
| 3 | Ab Initio Molecular Orbital Calculation on Dinuclear Gold(Ⅰ)Complexes──Metal-Metal Interaction and Electronic Structure of Binuclear Gold(Ⅰ)Complexes with Bridging Bidentate Ligands显示文摘AbInitioMolecularOrbitalCalculationonDinuclearGold(Ⅰ)Complexes——Metal┐MetalInteractionandElectronicStructureofBinuclearGold(Ⅰ... | GUO Chun xiao ** (Department of Chemistry, Jilin University, Changchun, 130023) Chi Keung Chan and Chi Ming Che (Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong) | 1997 | Chemical Research in Chinese Universities1997，13，2： | 0 |
| 4 | A nanonewton-scale biomimetic mechanosensor显示文摘Biomimetic mechanosensors have profound implications for various areas,including health care,prosthetics,human‒machine interfaces,and robotics.As one of the most important parameters,the sensitivity of mechanosensors is intrinsically determined by the detection resolution to mechanical force.In this manuscript,we expand the force detection resolution of current biomimetic mechanosensors from the micronewton to nanonewton scale.We develop a nanocrack-based electronic whisker-type mechanosensor that has a detection resolution of 72.2 nN.We achieve the perception of subtle mechanical stimuli,such as tiny objects and airflow,and the recognition of surface morphology down to a 30 nm height,which is the finest resolution ever reported in biomimetic mechanosensors.More importantly,we explore the use of this mechanosensor in wearable devices for sensing gravity field orientation with respect to the body,which has not been previously achieved by these types of sensors.We develop a wearable smart system for sensing the body’s posture and movements,which can be used for remote monitoring of falls in elderly people.In summary,the proposed device offers great advantages for not only improving sensing ability but also expanding functions and thus can be used in many fields not currently served by mechanosensors. | Chi Zhang Mengxi Wu Ming Li Lixuan Che Zhiguang Tan Di Guo Zhan Kang Shuye Cao Siqi Zhang Yu Sui Jining Sun Liding Wang Junshan Liu | 2023 | Microsystems & Nanoengineering2023，9，4： | 0 |
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