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| 1 | Treatment of meniscal tears: An evidence based approach显示文摘Treatment options for meniscal tears fall into three broad categories;non-operative,meniscectomy or meniscal repair.Selecting the most appropriate treatment for a given patient involves both patient factors(e.g.,age,co-morbidities and compliance)and tear characteristics(e.g.,location of tear/age/reducibility of tear).There is evidence suggesting that degenerative tears in older patients without mechanical symptoms can be effectively treated non-operatively with a structured physical therapy programme as a first line.Even if these patients later require meniscectomy they will still achieve similar functional outcomes than if they had initially been treated surgically.Partial meniscectomy is suitable for symptomatic tears not amenable to repair,and can still preserve meniscal function especially when the peripheral meniscal rim is intact.Meniscal repair shows 80%success at 2 years and is more suitable in younger patients with reducible tears that are peripheral(e.g.,nearer the capsular attachment)and horizontal or longitudinal in nature.However,careful patient selection and repair technique is required with good compliance to post-operative rehabilitation,which often consists of bracing and non-weight bearing for 4-6 wk. | Simon C Mordecai Nawfal Al-Hadithy Howard E Ware Chinmay M Gupte | 2014 | World Journal of Orthopedics2014，5，3： | 18 |
| 2 | Albumin as a prognostic marker for ulcerative colitis显示文摘AIM To evaluate the role of albumin at the time of ulcerative colitis(UC) diagnosis in predicting the clinical course of disease.METHODS Nationwide cohort of patients with newly diagnosed UC in the Veterans Affairs health care system was identified and divided into two categories: hypoalbuminemia(i.e.,≤ 3.5 gm/dl) or normal albumin levels(i.e.,> 3.5 gm/dl) at the time of UC diagnosis. The exposure of interest was presence of hypoalbuminemia defined asalbumin level ≤ 3.5 g/dl at the time of UC diagnosis. Patients were then followed over time to identify the use of ≥ 2 courses of corticosteroids(CS),thiopurines,anti-TNF medications and requirement of colectomy for UC management. RESULTS The eligible study cohort included 802 patients,but 92(11.4%) patients did not have their albumin levels checked at the time of UC diagnosis,and they were excluded. A total of 710 patients,who had albumin levels checked at time of UC diagnosis,were included in our study. Amongst them,536 patients had a normal albumin level and 174 patients had hypoalbuminemia. Patients with hypoalbuminemia at diagnosis had a higher likelihood of ≥ 2 courses of CS use(adjusted HR = 1.7,95%CI: 1.3-2.3),higher likelihood of thiopurine or anti-TNF use(adjusted HR = 1.72,95%CI: 1.23-2.40) than patients with normal albumin level at diagnosis. There was a trend of higher likelihood of colectomy in hypoalbuminemic patients,but it was not statistically significant(Adjusted HR = 1.7,95%CI: 0.90-3.25).CONCLUSION Hypoalbuminemia at disease diagnosis can serve as a prognostic marker to predict the clinical course of UC at the time of diagnosis. | Nabeel Khan Dhruvan Patel Yash Shah Chinmay Trivedi Yu-Xiao Yang | 2017 | World Journal of Gastroenterology2017，23，45： | 6 |
| 3 | Management of achilles tendon injury: A current concepts systematic review显示文摘Achilles tendon rupture has been on the rise over recent years due to a variety of reasons. It is a debilitating injury with a protracted and sometimes incomplete recovery. Management strategy is a controversial topic and evidence supporting a definite approach is limited. Opinion is divided between surgical repair and conservative immobilisation in conjunction with functional orthoses. A systematic search of the literature was performed. Pubmed, Medline and EmB ase databases were searched for Achilles tendon and a variety of synonymous terms. A recent wealth of reporting suggests that conservative regimens with early weight bearing or mobilisation have equivalent or improved rates of re-rupture to operative regimes. The application of dynamic ultrasound assessment of tendon gap may prove crucial in minimising re-rupture and improving outcomes. Studies employing functional assessments have found equivalent function between operative and conservative treatments. However, no specific tests in peak power, push off strength or athletic performance have been reported and whether an advantage in operative treatment exists remains undetermined. | Vivek Gulati Matthew Jaggard Shafic Said Al-Nammari Chika Uzoigwe Pooja Gulati Nizar Ismail Charles Gibbons Chinmay Gupte | 2015 | World Journal of Orthopedics2015，6，4： | 5 |
| 4 | Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency显示文摘 | Frederick Anokye-Danso Chinmay M. Trivedi Denise Juhr Mudit Gupta Zheng Cui Ying Tian Yuzhen Zhang Wenli Yang Peter J. Gruber Jonathan A. Epstein Edward E. Morrisey | 2011 | Cell Stem Cell2011，，4： | 2 |
| 5 | Impact of gut microbiome in the development and treatment of pancreatic cancer:Newer insights显示文摘The gut microbiome plays an important role in the variation of pharmacologic response.This aspect is especially important in the era of precision medicine,where understanding how and to what extent the gut microbiome interacts with drugs and their actions will be key to individualizing therapy.The impact of the composition of the gut microbiome on the efficacy of newer cancer therapies such as immune checkpoint inhibitors and chimeric antigen receptor T-cell treatment has become an active area of research.Pancreatic adenocarcinoma(PAC)has a poor prognosis even in those with potentially resectable disease,and treatment options are very limited.Newer studies have concluded that there is a synergistic effect for immunotherapy in combination with cytotoxic drugs,in the treatment of PAC.A variety of commensal microbiota can affect the efficacy of conventional chemotherapy and immunotherapy by modulating the tumor microenvironment in the treatment of PAC.This review will provide newer insights on the impact that alterations made in the gut microbial system have in the development and treatment of PAC. | Ayrton I Bangolo Chinmay Trivedi Ishan Jani Silvanna Pender Hirra Khalid Budoor Alqinai Alina Intisar Karamvir Randhawa Joseph Moore Nicoleta De Deugd Shaji Faisal SuchithBoodgere Suresh Parva Gopani Vignesh K Nagesh Tracy Proverbs-Singh Simcha Weissman | 2023 | World Journal of Gastroenterology2023，29，25： | 2 |
| 6 | Application of Dempster–Shafer theory in condition monitoring applications: a case study显示文摘 | Chinmay R Parikh Michael J Pont N Barrie Jones | 2001 | Pattern Recognition Letters2001，，6： | 1 |
| 7 | T p-e /QT ratio as an index of arrhythmogenesis显示文摘 | Prasad Gupta Chinmay Patel Harsh Patel Srinivasa Narayanaswamy Binu Malhotra Jared T. Green Gan-Xin Yan | 2008 | Journal of Electrocardiology2008，，6： | 1 |
| 8 | Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Ceils to Plurlpo- teney 显示文摘 | Frederick AD Chinmay MT | 2011 | Cell Stem Cell2011，，4： | 1 |
| 9 | Market equilibrium with Transaction Costs 显示文摘 | Sourav Chakraborty Nikhil R Devanur and Chinmay Karande | 2010 | Internet and Network E- conomics2010，，： | 1 |
| 10 | Dronedarone显示文摘 | Chinmay Patel Gan-Xin Yan Peter R. Kowey | 2009 | Circulation2009，，7： | 1 |
| 11 | Separation of nickel and copper from ammoniacal solutions through co-extraction and selective stripping using LIX84 as the extractant显示文摘 | Chinmay Parija PVRBhaskara Sarma | 2000 | Hydrometallurgy2000，54，： | 1 |
| 12 | Controllable Optical Properties of Polystyrene/PNIPAM-Gold Composite Nanoparticles显示文摘 | Chinmay Telang Todd Otanicar Lenore Dai Patrick Phelan Rajasekaran Swaminathan Mingmeng Zhang | 2015 | Plasmonics2015，，1： | 1 |
| 13 | T p-e /QT ratio as an index of arrhythmogenesis显示文摘 | Prasad Gupta Chinmay Patel Harsh Patel Srinivasa Narayanaswamy Binu Malhotra Jared T. Green Gan-Xin Yan | 2008 | Journal of Electrocardiology2008，，6： | 1 |
| 14 | Nonlinear buckling anal- ysis of hygrothermoelastic composite shell panels using finite ele- ment method 显示文摘 | Chinmay Kumar Kundu Jae-Hung Han | 2009 | Composites Part B : Engineering2009，40，4： | 1 |
| 15 | Case-based learning in pharmacology:Moving from teaching to leaming显示文摘 | MUKESHKUMAR B V CHINMAY J S | 2015 | Int J Appl Basic Med Res2015，5，： | 1 |
| 16 | Application of Dempster-Shafer Theory in Condition Monitoring Applications:a Case Study显示文摘 | CHINMAY R P MICHAEL J P JONES N B | 2001 | Pattern Recognition Lett2001，，22： | 1 |
| 17 | Application of Dempster–Shafer theory in condition monitoring applications: a case study显示文摘 | Chinmay R Parikh Michael J Pont N Barrie Jones | 2001 | Pattern Recognition Letters2001，，6： | 1 |
| 18 | Prolonged reactive oxygen species generation and nuclear factor - B activation after a high - fat,high - carbohydrate meal in the obese 显示文摘 | Chinmay P Husam G Shreyas R | 2007 | J Clin Endoerinol Metab2007，92，2： | 1 |
| 19 | Subclinical hypothyroidism in pregnancy: An emerging problem in Southern West Bengal: A cross-sectional study显示文摘 | Ratan Mandal Debasish Bhar Anjan Das Sandip Basunia Sudeshna Kundu Chinmay Mahapatra | 2016 | Journal of Natural Science, Biology and Medicine2016，，： | 1 |
| 20 | Separation of Nickel and Copper from Ammoniacal Solutions through Coextraction and Selective Stripping Using Lix84 as the Extractant显示文摘 | CHINMAY PARIJA P V R BHASKARA SARMA | 2000 | Hydrometallurgy2000，54，3： | 1 |
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