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| 1 | First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases显示文摘AIM To evaluate rebleeding, primary failure(PF) and mortality of patients in whom over-the-scope clips(OTSCs) were used as first-line and second-line endoscopic treatment(FLET, SLET) of upper and lower gastrointestinal bleeding(UGIB, LGIB).METHODS A retrospective analysis of a prospectively collected database identified all patients with UGIB and LGIB in a tertiary endoscopic referral center of the University of Freiburg, Germany, from 04-2012 to 05-2016(n= 93) who underwent FLET and SLET with OTSCs. The complete Rockall risk scores were calculated from patients with UGIB. The scores were categorized as < or ≥ 7 and were compared with the original Rockall data. Differences between FLET and SLET were calculated. Univariate and multivariate analysis were performed to evaluate the factors that influenced rebleeding after OTSC placement.RESULTS Primary hemostasis and clinical success of bleeding lesions(without rebleeding) was achieved in 88/100(88%) and 78/100(78%), respectively. PF was significantly lower when OTSCs were applied as FLET compared to SLET(4.9% vs 23%, P = 0.008). In multivariate analysis, patients who had OTSC placement as SLET had a significantly higher rebleeding risk compared to those who had FLET(OR 5.3; P = 0.008). Patients with Rockall risk scores ≥ 7 had a significantly higher in-hospital mortality compared to those with scores < 7(35% vs 10%, P = 0.034). No significant differences were observed in patients with scores < or ≥ 7 in rebleeding and rebleeding-associated mortality.CONCLUSION Our data show for the first time that FLET with OTSC might be the best predictor to successfully prevent rebleeding of gastrointestinal bleeding compared to SLET. The type of treatment determines the success of primary hemostasis or primary failure. | Hans-Jürgen Richter-Schrag Torben Glatz Christine Walker Andreas Fischer Robert Thimme | 2016 | World Journal of Gastroenterology2016，22，41： | 11 |
| 2 | A randomised control trial of a self-management program for people with a chronic illness from Vietnamese, Chinese, Italian and Greek backgrounds显示文摘 | Hal Swerissen John Belfrage Amanda Weeks Lucinda Jordan Christine Walker John Furler Brian McAvoy Meredith Carter Chris Peterson | 2006 | Patient Education and Counseling2006，，1： | 2 |
| 3 | Effects of early childhood psychosocial stimulation and nutritional supplementation on cognition and education in growth-stunted Jamaican children: prospective cohort study显示文摘 | Susan P Walker Susan M Chang Christine A Powell Sally M Grantham-McGregor | 2005 | The Lancet2005，，9499： | 1 |
| 4 | Risk in supply networks显示文摘 | Christine Harland Richard Brenchley Helen Walker | 2003 | Journal of Purchasing and Supply Management2003，，2： | 1 |
| 5 | Continuing low colon cancer incidence in African populations显示文摘 | Isidor Segal Christine A Edwards Alexander R.P Walker | 2000 | The American Journal of Gastroenterology2000，，4： | 1 |
| 6 | Outsourcing: assessing the risks and benefits for organisations, sectors and nations显示文摘 | Christine Harland Louise Knight Richard Lamming Helen Walker | 2005 | International Journal of Operations & Production Management2005，，9： | 1 |
| 7 | Risk in supply networks, 显示文摘 | Christine Harland Richard Brenchley Helen Walker | 2003 | Journal of Purchasing & Supply Management2003，9，： | 1 |
| 8 | Molecular analysis of 46,XY females and regional assignment of a new Y-chromosome-specific probe显示文摘 | Michael A. Cantrell James N. Bicknell Roberta A. Pagon David C. Page David C. Walker Howard M. Saal Arthur B. Zinn Christine M. Disteche | 1989 | Human Genetics1989，，1： | 1 |
| 9 | Light regulation of anthocyanin flavonoid and phnolic acid biosynthesis in potato minitubers in vitro 显示文摘 | Christin E E John R L Walker J E | 1998 | Australia Journal of plant Physiol1998，25，： | 1 |
| 10 | Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3)显示文摘 | Tara L. Davis John R. Walker Peter Loppnau Christine Butler-Cole Abdellah Allali-Hassani Sirano Dhe-Paganon | 2008 | Structure2008，，6： | 1 |
| 11 | Risk in supply networks显示文摘 | Christine Harland Richard Brenchley and Helen Walker | 2003 | Journal of Purchasing and Supply Management2003，9，2： | 1 |
| 12 | Toxoplasma gondii Alba proteins are involved in translational control of gene expression显示文摘 | Mathieu Gissot Robert Walker Stephane Delhaye Tchilabalo Dilezitoko Alayi Ludovic Huot David Hot Isabelle Callebaut Christine Schaeffer-Reiss Alain Van Dorsselaer Stanislas Tomavo | 2013 | Journal of Molecular Biology2013，，： | 1 |
| 13 | Risk in supply networks 显示文摘 | Christine Harland Richard Brenchley Helen Walker | 2003 | Journal of Purchasing and Supply Management2003，9，2： | 1 |
| 14 | Promoting competitive markets:The role of public procurement 显示文摘 | Nigel Caldwell Helen Walker Christine Harland louise Knight Jurong Zheng Tim Wakeley | 2005 | Journal of Purchasing & Supply Management2005，，11： | 1 |
| 15 | Natural history and CT appearance of Aortic Intramural Hemotoma显示文摘 | Christine P Walker TG Sanjeeva P | 2009 | Radiographics2009，29，： | 1 |
| 16 | Light regulation of anthocyanin,flavonoid and phnolic acid biosynthesis in potato minitubers in vitro显示文摘 | JOHN R L WALKER J E | 1998 | Australia Journal of Plant Physiol1998，25，： | 1 |
| 17 | Risk in supply networks显示文摘 | Christine Harland Richard Brenchley Helen Walker | 2003 | Journal of Purchasing and Supply Management2003，9，2： | 1 |
| 18 | 酚化合物对烟草燃烧的影响显示文摘 | Christine A. LITTLE Alexander J. Dyakonov Rana T. Walker Florian R. Perini D. Scott Passer Jun Guan 吴晓芸(译) 曹建平(校) | 2006 | 中国烟草学报2006，12，4： | 0 |
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