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| 1 | Inhibition of angiogenesis and HCT-116 xenograft tumor growth in mice by kallistatin显示文摘AIM: To investigate the inhibitory effect of kallistatin (KAL) on angiogenesis and HCT-116 xenograft tumor growth. METHODS: Heterotopic tumors were induced by subcutaneous injection of 2 × 106 HCT-11 cells in mice. Seven days later, 2 × 1011 rAAV-GFP or rAAV-KAL was injected intratumorally (n = 5 for each group). The mice were sacrificed at d 28, by which time the tumors in the rAAV-GFP group had grown to beyond 5% of the total body weight. Tumor growth was measured by calipers in two dimensions. Tumor angiogenesis was determined with tumor microvessel density (MVD) by immunohistology. Tumor cell proliferation was assessed by Ki-67 staining. RESULTS: Intratumor injection of rAAV-KAL inhibited tumor growth in the treatment group by 78% (171 ± 52 mm3) at d 21 after virus infection compared to the control group (776 ± 241 mm3). Microvessel density was significantly inhibited in tumor tissues treated with rAAV-KAL. rAAV-KAL also decreased the proportion of proliferating cells (Ki-67 positive cells) in tumors compared with the control group.CONCLUSION: rAAV-mediated expression of KAL inhibits the growth of colon cancer by reducing angiogenesis and proliferation of tumor cells, and may provide a promising anti-angiogenesis-based approach to the treatment of metastatic colorectal cancer. | Yong Diao Jian Ma Wei-Dong Xiao Jia Luo Xin-Yan Li Kin-Wah Chu Peter WC Fung Nagy Habib Farzin Farzaneh Rui-An Xu | 2007 | World Journal of Gastroenterology2007，13，34： | 15 |
| 2 | Seasonal Variability of the Yellow Sea/East China Sea Surface Fluxes and Thermohaline Structure显示文摘We use the U.S. Navy's Master Oceanographic Observation Data Set (MOODS) for the Yellow Sea/East China Sea (YES) to investigate the climatological water mass features and the seasonal and non-seasonal variabilities of the thermohaline structure, and use the Comprehensive Ocean-Atmosphere Data Set (COADS) from 1945 to 1989 to investigate the linkage between the fluxes (momentum, heat, and moisture) across the air-ocean interface and the formation of the water mass features. After examining the major current systems and considering the local bathymetry and water mass properties, we divide YES into five regions: East China Sea (ECS) shelf, Yellow Sea (YS) Basin, Cheju bifurcation (CB) zone, Taiwan Warm Current (TWC) region, Kuroshio Current (KG) region. The long term mean surface heat balance corresponds to a heat loss of 30 W m-2 in the ESC and CB regions, a heat loss of 65 W m-2 in the KG and TWC regions, and a heat gain of 15 W m-2 in the YS region. The surface freshwater balance is defined by precipitation minus evaporation. The annual water loss from the surface for the five subareas ranges from 1.8 to 4 cm month-1. The fresh water loss from the surface should be compensated for from the river run-off. The entire water column of the shelf region (ECS, YS, and CB) undergoes an evident seasonal thermal cycle with maximum values of temperature during summer and maximum mixed layer depths during winter. However, only the surface waters of the TWC and KG regions exhibit a seasonal thermal cycle.We also found two different relations between surface salinity and the Yangtze River run-off, namely, out-of-phase in the East China Sea shelf and in-phase in the Yellow Sea. This may confirm an earlier study that the summer fresh water discharge from the Yangtze River forms a relatively shallow, low salinity plume-like structure extending offshore on average towards the northeast. | Peter CHU 陈玉春 Akira KUNINAKA | 2005 | Advances in Atmospheric Sciences2005，22，1： | 12 |
| 3 | South China Sea Warm Pool in Boreal Spring显示文摘SouthChinaSeaWarmPoolinBorealSpringPeterC.ChuandC.-P.ChangNavalPostgraduateSchol,Monterey,CA93943,USA,October23,1996ReceivedN... | Peter C. Chu C. P. Chang | 1997 | Advances in Atmospheric Sciences1997，14，2： | 5 |
| 4 | 西北太平洋等位势密度面上的东向副热带逆流显示文摘用美国海军高分辨率气候月平均温盐资料和等位势密度面P-矢量方法,计算了西北太平洋各月等位势密度面环流.主要讨论西北太平洋副热带流涡内部东向副热带逆流(简称:STCC)的空间分布、垂直结构、体积输送及其附近的涡旋现象.计算结果很好地再现了STCC的一些观测特征,并且还揭示了STCC在等位势密度面上呈现的一些新现象:(1)在24.6 σθ面上,STCC的空间分布、源地和流动态势都有很强的季节变化,1-3月份不存在STCC;(2)5-10月,日本以南黑潮逆流的一个分支汇入了STCC,使得STCC的流速增强,流幅显著地加宽;(3)流速矢量场明显地表现出:STCC和它附近的一些涡旋伴随而生,STCC存在时它附近总伴随着一些涡旋,当STCC消失时涡旋也就消失了;(4)通过137.5°E断面,STCC的输送量夏季最强,8月份最大输送量达6.9 Sv(1 Sv三106m3/s),春、秋季较弱,4和11月份的输送量分别为1.7和1.6 Sv,输送主要集中在24.0≤σθ≤25.0面之间;(5)纬向流沿137.5°E断面的分布表明,STCC的流核位于24.3-24.7σθ之间. | 李荣凤 游小宝 Peter Chu | 2004 | 中国科学(D辑)2004，34，11： | 4 |
| 5 | Geostrophic meridional transport in tropical Northwest Pacific based on Argo profiles显示文摘Absolute geostrophic currents in the North Pacific Ocean were calculated using P-vector method from newly gridded Argo profiling float data collected during 2004-2009. The meridional volume transport of geostrophic currents differed significantly from the classical Sverdrup balance, with differences of 10×106 -20×106 m3 /s in the interior tropical Northwest Pacific Ocean. Analyses showed that errors of wind stress estimation could not explain all of the differences. The largest differences were found in the areas immediately north and south of the bifurcation latitude of the North Equatorial Current west of the dateline, and in the recirculation area of the Kuroshio and its extension, where nonlinear eddy activities were robust. Comparison of the geostrophic meridional transport and the wind-driven Sverdrup meridional transport in a high-resolution OFES simulation showed that nonlinear effects of the ocean circulation were the most likely reason for the differences. It is therefore suggested that the linear, steady wind-driven dynamics of the Sverdrup theory cannot completely explain the meridional transport of the interior circulation of the tropical Northwest Pacific Ocean. | 张志春 袁东亮 Peter C. CHU | 2013 | Chinese Journal of Oceanology and Limnology2013，31，3： | 4 |
| 6 | Argo floats revealing bimodality of large-scale mid-depth circulation in the North Atlantic显示文摘Analysis of Argo float trajectories at 1 000 m and temperature at 950 m in the North Atlantic between November 2003 and January 2005 demonstrates the existence of two different circulation modes with fast transition between them. Each mode has a pair of cyclonic-anticyclonic gyres. The difference is the location of the cyclonic gyre. The cyclonic gyre stretches from southeast to northwest in the first mode and from the southwest to the northeast in the second mode. The observed modes strongly affect the heat and salt transport in the North Atlantic. In particular, the second mode slows down the westward transport of the warm and saline water from the Mediterranean Sea. | CHU Peter C IVANOV Leonid M MELNICHENKO Oleg V LI Rongfeng | 2008 | Acta Oceanologica Sinica2008，27，2： | 4 |
| 7 | Fungal diversity notes 1–110:taxonomic and phylogenetic contributions to fungal species显示文摘This paper is a compilation of notes on 110 fungal taxa,including one new family,10 new genera,and 76 new species,representing a wide taxonomic and geographic range.The new family,Paradictyoarthriniaceae is introduced based on its distinct lineage in Dothideomycetes and its unique morphology.The family is sister to Biatriosporaceae and Roussoellaceae.The new genera are Allophaeosphaeria(Phaeosphaeriaceae),Amphibambusa(Amphisphaeriaceae),Brunneomycosphaerella(Capnodiales genera incertae cedis),Chaetocapnodium(Capnodiaceae),Flammeascoma(Anteagloniaceae),Multiseptospora(Pleosporales genera incertae cedis),Neogaeumannomyces(Magnaporthaceae),Palmiascoma(Bambusicolaceae),Paralecia(Squamarinaceae)and Sarimanas(Melanommataceae).The newly described species are the Ascomycota Aliquandostipite manochii,Allophaeosphaeria dactylidis,A.muriformia,Alternaria cesenica,Amphibambusa bambusicola,Amphisphaeria sorbi,Annulohypoxylon thailandicum,Atrotorquata spartii,Brunneomycosphaerella laburni,Byssosphaeria musae,Camarosporium aborescentis,C.aureum,C.frutexensis,Chaetocapnodium siamensis,Chaetothyrium agathis,Colletotrichum sedi,Conicomyces pseudotransvaalensis,Cytospora berberidis,C.sibiraeae,Diaporthe thunbergiicola,Diatrype palmicola,Dictyosporium aquaticum,D.meiosporum,D.thailandicum,Didymella cirsii,Dinemasporium nelloi,Flammeascoma bambusae,Kalmusia italica,K.spartii,Keissleriella sparticola,Lauriomyces synnematicus,Leptosphaeria ebuli,Lophiostoma pseudodictyosporium,L.ravennicum,Lophiotrema eburnoides,Montagnula graminicola,Multiseptospora thailandica,Myrothecium macrosporum,Natantispora unipolaris,Neogaeumannomyces bambusicola,Neosetophoma clematidis,N.italica,Oxydothis atypica,Palmiascoma gregariascomum,Paraconiothyrium nelloi,P.thysanolaenae,Paradictyoarthrinium tectonicola,Paralecia pratorum,Paraphaeosphaeria spartii,Pestalotiopsis digitalis,P.dracontomelon,P.italiana,Phaeoisaria pseudoclematidis,Phragmocapnias philippinensis,Pseudocamarosporium cotinae,Pseudocercospora tamarindi,Pseudotrichia rubriostiolata,P.thailandica,Psiloglonium multiseptatum,Saagaromyces mangrovei,Sarimanas pseudofluviatile,S.shirakamiense,Tothia spartii,Trichomerium siamensis,Wojnowicia dactylidicola,W.dactylidis and W.lonicerae.The Basidiomycota Agaricus flavicentrus,A.hanthanaensis,A.parvibicolor,A.sodalis,Cantharellus luteostipitatus,Lactarius atrobrunneus,L.politus,Phylloporia dependens and Russula cortinarioides are also introduced.Epitypifications or reference specimens are designated for Hapalocystis berkeleyi,Meliola tamarindi,Pallidocercospora acaciigena,Phaeosphaeria musae,Plenodomus agnitus,Psiloglonium colihuae,P.sasicola and Zasmidium musae while notes and/or new sequence data are provided for Annulohypoxylon leptascum,A.nitens,A.stygium,Biscogniauxia marginata,Fasciatispora nypae,Hypoxylon fendleri,H.monticulosum,Leptosphaeria doliolum,Microsphaeropsis olivacea,Neomicrothyrium,Paraleptosphaeria nitschkei,Phoma medicaginis and Saccotheciaceae.A full description of each species is provided with light micrographs(or drawings).Molecular data is provided for 90 taxa and used to generate phylogenetic trees to establish a natural classification for species. | Jian Kui Liu Kevin D.Hyde E.B.Gareth Jones Hiran A.Ariyawansa Darbhe J.Bhat Saranyaphat Boonmee Sajeewa S.N.Maharachchikumbura Eric H.C.McKenzie Rungtiwa Phookamsak Chayanard Phukhamsakda Belle Damodara Shenoy Mohamed A,Abdel-Wahab Bart Buyck Jie Chen K.W.Thilini Chethana Chonticha Singtripop Dong Qin Dai Yu Cheng Dai Dinushani ADaranagama Asha J.Dissanayake Mingkwan Doilom Melvina J.D’souza Xin Lei Fan Ishani DGoonasekara Kazuyuki Hirayama Sinang Hongsanan Subashini C.Jayasiri Ruvishika S.Jayawardena Samantha C.Karunarathna Wen Jing Li Ausana Mapook Chada Norphanphoun Ka Lai Pang Rekhani H.Perera Derek Peršoh Umpava Pinruan Indunil CSenanayake Sayanh Somrithipol Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Danushka Udayanga Nalin N.Wijayawardene Dhanuska Wanasinghe Komsit Wisitrassameewong Xiang Yu Zeng Faten AAbdel-Aziz Slavomir Adamčík Ali H.Bahkali Nattawut Boonyuen Timur Bulgakov Philippe Callac Putarak Chomnunti Katrin Greiner Akira Hashimoto Valerie Hofstetter Ji Chuan Kang David Lewis Xing Hong Li Xing Zhong Liu Zuo Yi Liu Misato Matsumura Peter E.Mortimer Gerhard Rambold Emile Randrianjohany Genki Sato Veera Sri-Indrasutdhi Cheng Ming Tian Annemieke Verbeken Wolfgang von Brackel Yong Wang Ting Chi Wen Jian Chu Xu Ji Ye Yan Rui Lin Zhao Erio Camporesi | 2015 | Fungal Diversity2015，，3： | 3 |
| 8 | Improvement of short-term forecasting in the northwest Pacific through assimilating Argo data into initial fields显示文摘在温度和咸度的短期的预报精确性上吸收南船座数据进起始的域的影响是使用西方的诺思太平洋的一个预报系统估计的份量上,在有一个概括坐标系统(POMgcs ) 的普林斯顿海洋模型的库上。这个系统使用顺序的 multigrid 三维变化(3DVAR ) 吸收观察数据的分析计划。二个数字实验在吸收数据进起始的域的进程除常规温度和海表面温度(SST ) 以外有或没有南船座温度和咸度侧面数据被进行。预报错误被在预报时期期间使用独立温度和咸度侧面估计,包括水平地平均的根均方差( H-RMSEs )的垂直分布和垂直地平均的吝啬的错误( MEs )和空间地平均的根均方差( S-RMSEs )的时间的变化的水平分布。在二个实验之间的比较证明南船座数据的吸收显著地改进预报精确性,与为温度,和咸度最大的 H-RMSE 的 24% 减小预报更显然被改进,平均深入地比 300 m 浅的为 H-RMSEs 50% 落下。如此的改进被温度和咸度的相对一致的采样在时空从南船座流浪者引起。 | FU Hongli CHU Peter C HAN Guijun HE Zhongjie LI Wei ZHANG Xuefeng | 2013 | Acta Oceanologica Sinica2013，32，7： | 2 |
| 9 | A comparison study of improved Hilbert–Huang transform and wavelet transform: Application to fault diagnosis for rolling bearing显示文摘 | Z.K. Peng Peter W. Tse F.L. Chu | 2005 | Mechanical Systems and Signal Processing2005，，5： | 2 |
| 10 | Thermal fronts and cross-frontal heat flux in the southern Huanghai Sea and the East China Sea显示文摘Synoptic features in/around thermal fronts and cross-frontal heat fluxes in the southern Huanghai/Yellow Sea and East China Sea (HES) were examined using the data collected from four airborne expendable bathythermograph surveys with horizontal approxmately 35 km and vertical 1 m(from the surface to 400 m deep) spacings.Since the fronts are strongly affected by HES current system, the synoptic thermal features in/around them represent the interaction of currents with surrounding water masses. These features can not be obtained from climatological data. The identified thermal features are listed as follows: (1) multiple boundaries of cold water, asymmetric thermocline intrusion, locally-split front by homogeneous water of approxmately 18 ℃, and mergence of the front by the Taiwan Warm Current in/around summertime southern Cheju-Changjiang/Yangtze front and Tsushima front; (2) springtime frontal eddy-like feature around Tsushima front; (3) year-round cyclonic meandering and summertime temperature-inversion at the bottom of the surface mixed layer in Cheju-Tsushima front; and (4) multistructure of Kuroshio front. In the Kuroshio front the mean variance of vertical temperature gradient is an order of degree smaller than that in other HES fronts.The southern Cheju-Changjiang front and Cheju-Tsushima front are connected with each other in the summer with comparable cross-frontal temperature gradient. However, cross-frontal heat flux and lateral eddy diffusivity are stronger in the southern Cheju-Changjiang front. The cross-frontal heat exchange is the largest in the mixing zone between the modified Huanghai Sea bottom cold water and the Tsushima Warm Current, which is attributable to enhanced thermocline intrusions. | PARK Sunghyea CHU Peter C | 2008 | Acta Oceanologica Sinica2008，27，5： | 2 |
| 11 | Laparoscopic Distal Pancreatectomy: Trends and Lessons Learned Through an 11-Year Experience显示文摘 | Peter J. Kneuertz Sameer H. Patel Carrie K. Chu Sarah B. Fisher Shishir K. Maithel Juan M. Sarmiento Sharon M. Weber Charles A. Staley David A. Kooby | 2012 | Journal of the American College of Surgeons2012，，2： | 2 |
| 12 | A comparison study of improved Hilbert-Huang transform and wavelet transform:Application to fault diagnosis for rolling bearing显示文摘 | Peng Z K Peter W T Chu F L | | 0，，5： | 1 |
| 13 | A note on EOQ models for deteriorating items under stock dependent selling rate显示文摘 | Peter Chu Shaw-ping Lan | 2000 | European Journal of Operational Research2000，124，： | 1 |
| 14 | A note on EOQ models for deteriorating items under stock dependent selling rate显示文摘 | Kun-Jen Chung Peter Chu Shaw-Ping Lan | 2000 | European Journal of Operational Research2000，，124： | 1 |
| 15 | A comparison study of improved Hilbert-Huang transform and wavelet transform:Application to fault diagnosis for rolling bearing显示文摘 | Peng Z K Peter W T Chu F L | 2005 | Mechanical Systems and Signal Processing2005，19，： | 1 |
| 16 | An improved Hilbert-Huang transform and its application in vibration signal analysis显示文摘 | Peng Z K Peter W T Chu F L | 2005 | Journal of Sound and Vibration2005，286，： | 1 |
| 17 | A comparison study of improved Hilbert-Huang transform and wavelet trans- form: application to fault diagnosis for rolling bearing 显示文摘 | Peng Z K Peter W Chu F L | 2005 | Mechanical Systems and Signal Processing2005，19，1： | 1 |
| 18 | An Improved Hilbert-Huang Transform and Its Application in Vibration Analysis显示文摘 | Peng Z K Peter W T Chu F L | 2005 | Journal of Sound and Vibration2005，286，12： | 1 |
| 19 | Prognostic significance of a pretreatment hematologic profile in patients with head and neck cancer显示文摘 | Ming-Huang Chen Peter Mu-Hsin Chang Po-Min Chen Cheng-Hwai Tzeng Pen-Yuan Chu Shyue-Yih Chang Muh-Hwa Yang | 2009 | Journal of Cancer Research and Clinical Oncology2009，，： | 1 |
| 20 | Noiseand vibration analysis of a disc-brakesyste m using a stic-slip friction model involving coupling stiffness 显示文摘 | Manish Paliwal Ajay Mahajan Jarlen Don Tsuchin Chu Peter Filip | 2005 | Journal of Sound and Vibration2005，282，： | 1 |
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