|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Indoleamine 2,3-dioxygenase (IDO) is essential for dendritic cell activation and chemotactic responsiveness to chemokines显示文摘Indoleamine 2, 3-dioxygenase (IDO) is a rate-limiting enzyme for the tryptophan catabolism. In human and murine cells, IDO inhibits antigen-specific T cell proliferation in vitro and suppresses T cell responses to fetal alloantigens during murine pregnancy. In mice, IDO expression is an inducible feature of specific subsets of dendritic cells (DCs), and is important for T cell regulatory properties. However, the effect of IDO and tryptophan deprivation on DC func- tions remains unknown. We report here that when tryptophan utilization was prevented by a pharmacological inhibitor of IDO, 1-methyl tryptophan (1MT), DC activation induced by pathogenic stimulus lipopolysaccharide (LPS) or inflam- matory cytokine TNF-α was inhibited both phenotypically and functionally. Such an effect was less remarkable when DC was stimulated by a physiological stimulus, CD40 ligand. Tryptophan deprivation during DC activation also regu- lated the expression of CCR5 and CXCR4, as well as DC responsiveness to chemokines. These results suggest that tryptophan usage in the microenvironment is essential for DC maturation, and may also play a role in the regulation of DC migratory behaviors. | Shih Ling HWANG Nancy Pei-Yee CHUNG Jacqueline Kwai-Yi CHAN Chen-Lung Steve LIN | 2005 | Cell Research2005，15，3： | 11 |
| 2 | Impacts of different drying strategies on drying characteristics,the retention of bio-active ingredient and colour changes of dried Roselle显示文摘The drying kinetics of Roselle(Hibiscus sabdariffa L) of variety Terengganu(UMKL-1) and the quality attribution of Roselle were studied. The experiments were conducted using four different drying methods, including solar greenhouse drying(SD), solar greenhouse with intermittent heat pump drying(SIHP), hot air drying(HA) and heat pump drying(HP). Among the four drying methods, HP achieved the highest drying rate at a range from0.054 g H_2 O·(g DM)^(-1) ·min^(-1) to 0.212 g H_2 O·(g DM)^(-1)·min^(-1) while SD had the lowest drying rate, measured at 0.042 g H_2 O·(g DM)^(-1)·min^(-1).The analysis on colour kinetics revealed that there is no significant colour loss(p > 0.05) observed from HP's dried Roselle. Greater amount of flavonoid compounds i.e. protocatechuic acid was found in SD and SIHP dried finished product whereas HP's dried Roselle contains higher percentage of catechin as compared to other drying methods. | Thing Chai Tham Mei Xiang Ng Shu Hui Gan Lee Suan Chua Ramlan Aziz Luqman Chuah Abdullah Sze Pheng Ong Nyuk Ling Chin Chung Lim Law | 2018 | Chinese Journal of Chemical Engineering2018，26，2： | 7 |
| 3 | High Levels of Hepatitis B Surface Antigen Increase Risk of Hepatocellular Carcinoma in Patients With Low HBV Load显示文摘 | Tai–Chung Tseng Chun–Jen Liu Hung–Chih Yang Tung–Hung Su Chia–Chi Wang Chi–Ling Chen Stephanie Fang–Tzu Kuo Chen–Hua Liu Pei–Jer Chen Ding–Shinn Chen Jia–Horng Kao | 2012 | Gastroenterology2012，，5： | 6 |
| 4 | Serum Hepatitis B Surface Antigen Levels Predict Surface Antigen Loss in Hepatitis B e Antigen Seroconverters显示文摘 | Tai–Chung Tseng Chun–Jen Liu Tung–Hung Su Chia–Chi Wang Chi–Ling Chen Pei–Jer Chen Ding–Shinn Chen Jia–Horng Kao | 2011 | Gastroenterology2011，，2： | 4 |
| 5 | Preliminary nitrite, nitrate and colour analysis of Malaysian edible bird’s nest显示文摘The high nitrite content in edible bird’s nests is a major concern to the local swiftlet industry.It lowers the price of the edible bird’s nests and it brings severe health hazards to consumers and farmers.This research investigated the nitrite and nitrate contents of eight types of local edible bird’s nests by using ion chromatography system and evaluating its colour using the CIE system in L^*a^*b^*parameters.The nitrite content obtained ranged from 5.7 lg/g for the house nests to 843.8 lg/g for the cave nests.The nitrate content for the house and cave nests was 98.2 lg/g and 36,999.4 lg/g,respectively.The cave nests with darker and redder colour had higher nitrite and nitrate contents than the brighter and more yellow house nests.This likely suggests that the nitrite and nitrate contents have correlations with edible bird’s nests colour.Correlations studies suggested that the nitrite content had high correlations with colour parameters,L^*a^*b^*of edible bird’s nests at significant level of P<0.10.These findings suggest that edible bird’s nests’colour may be a useful indicator for measuring nitrite and nitrate contaminations. | Meei Chien Quek Nyuk Ling Chin Yus Aniza Yusof Sheau Wei Tan Chung Lim Law | 2015 | Information Processing in Agriculture2015，2，1： | 3 |
| 6 | Brain MRI of hippocampal volumetry in patients with refractory temporal lobe epilepsy显示文摘Objective To detect for hippocampal sclerosis presurgically in a group of patients with refractory temporal lobe epilepsy Methods Eighty four consecutive patients with refractory temporal lobe epilepsy were subjected to brain MRI of hippocampal volumetry A ratio of smaller to larger hippocampal volume was determined and unilateral hippocampal atrophy (HA) was diagnosed if the ratio is less than 0 91 Results Unilateral HA was diagnosed in 42 patients (50%) and bilateral HA in 1 patient Other MRI abnormalities were detected in 18 patients with or without coexisting HA Conclusions Hippocampal sclerosis can be detected presurgically in many patients by brain MRI Additional abnormalities not detected by brain CT can also be | Ka Kui Philip Ng, Kwok Wing Tang, Yuk Ling James Cheung and Patrick Chung Ki Li | 2000 | Chinese Medical Journal2000，，3： | 3 |
| 7 | Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads显示文摘 | Tai‐Chung Tseng Chun‐Jen Liu Hung‐Chih Yang Tung‐Hung Su Chia‐Chi Wang Chi‐Ling Chen Cheng‐An Hsu Stephanie Fang‐Tzu Kuo Chen‐Hua Liu Pei‐Jer Chen Ding‐Shinn Chen Jia‐Horng Kao | 2012 | Hepatology2012，，： | 2 |
| 8 | CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development显示文摘尽管 HCO 3− 被知道为早胚胎开发被要求,它的准确角色留下逃犯。这里,我们报导 HCO 3− 在在 preimplantation 胚胎开发期间通过调停 CFTR 的流入调整 miR-125b 表示充当环境暗示。结果证明在 preimplantation 胚胎开发的 HCO 3− 的效果能被介入压制一条 HCO 3−-conducting 隧道的函数, CFTR,由一个特定的禁止者或基因大美人。细胞外的 HCO 3− 的移动或 CFTR 的抑制在 2 个房间阶段老鼠胚胎减少 miR-125b 表示。miR-125b 击倒模仿 HCO 3− 移动和 CFTR 抑制的效果,当 miR-125b 先锋的注射颠倒它时。在人和老鼠胚胎的 miR-125b upregulates p53 串联的 Downregulation。miR-125b 的激活被显示被 sAC/PKA-dependent 调停 NF-κ 的原子 shuttling; B。这些结果在在 preimplantation 胚胎开发期间连接环境 HCO 3− 到 miR-125b 的激活的信号 transduction 揭示了 CFTR 的一个关键角色并且在 miRNAs 的规定显示了离子隧道的重要性。 | Yong Chao Lu Hui Chen Kin Lam Fok Lai Ling Tsang Mei Kuen Yu Xiao Hu Zhang Jing Chen Xiaohua Jiang Yiu Wa Chung Alvin Chun Hang Ma Anskar Yu Hung Leung He Feng Huang Hsiao Chang Chan | 2012 | Cell Research2012，22，10： | 2 |
| 9 | Direct numerical simulation of a three-dimensional temporal mixing layer with particle dispersion显示文摘 | Ling W Chung J N Troutt T R | 1998 | J Fluid Mech1998，358，： | 1 |
| 10 | Direct numerical simulation of a three-dimensional temporal mixing layer with particle dispersion 显示文摘 | Ling W Chung J N Troutt T R | 1998 | Journal of Fluid Mechanics1998，358，： | 1 |
| 11 | Admission hyperglycemia predicts poorer short‐ and long‐term outcomes after primary percutaneous coronary intervention for ST ‐elevation myocardial infarction显示文摘 | Pei‐Chi Chen Su‐Kiat Chua Huei‐Fong Hung Chung‐Yen Huang Chiu‐Mei Lin Shih‐Ming Lai Yen‐Ling Chen Jun‐Jack Cheng Chiung‐Zuan Chiu Shih‐Huang Lee Huey‐Ming Lo Kou‐Gi Shyu | 2014 | J Diabetes Invest2014，，1： | 1 |
| 12 | A Simple Printed Ultrawideband Antenna with a Quasi-Transmission Line Section 显示文摘 | Ling C W Chung S | 2009 | IEEE Trans Antennas Propag2009，57，10： | 1 |
| 13 | High Levels of Hepatitis B Surface Antigen Increase Risk of Hepatocellular Carcinoma in Patients With Low HBV Load显示文摘 | Tai–Chung Tseng Chun–Jen Liu Hung–Chih Yang Tung–Hung Su Chia–Chi Wang Chi–Ling Chen Stephanie Fang–Tzu Kuo Chen–Hua Liu Pei–Jer Chen Ding–Shinn Chen Jia–Horng Kao | 2012 | Gastroenterology2012，，5： | 1 |
| 14 | Draw solutions for forward osmosis processes: developments, challenges, and prospects for the future 显示文摘 | Ge Q Ling M Chung T | 2013 | J Membr Sci2013，442，： | 1 |
| 15 | Hepatitis C viral infection increases the risk of lymphoid‐neoplasms: A population‐based cohort study显示文摘 | Tung‐Hung Su Chun‐Jen Liu Tai‐Chung Tseng Shih‐Wan Chou Chen‐Hua Liu Hung‐Chih Yang Shang‐Ju Wu Pei‐Jer Chen Ding‐Shinn Chen Chi‐Ling Chen Jia‐Horng Kao | 2016 | Hepatology2016，，3： | 1 |
| 16 | Beneficial effects of regular Tai Chi exercise on musculoskeletal system显示文摘 | Ling Qin Wingyee Choy Kwoksui Leung Ping Chung Leung Szeki Au Wingyin Hung Maximilian Dambacher Kaiming Chan | 2005 | Journal of Bone and Mineral Metabolism2005，，2： | 1 |
| 17 | High Levels of Hepatitis B Surface Antigen Increase Risk of Hepatocellular Carcinoma in Patients With Low HBV Load显示文摘 | Tai–Chung Tseng Chun–Jen Liu Hung–Chih Yang Tung–Hung Su Chia–Chi Wang Chi–Ling Chen Stephanie Fang–Tzu Kuo Chen–Hua Liu Pei–Jer Chen Ding–Shinn Chen Jia–Horng Kao | 2012 | Gastroenterology2012，，5： | 1 |
| 18 | Highly water- soluble magnetic nanopartieles as novel draw solutes in forward osmosis for water reuse显示文摘 | Ling Mingming Wang K Y Chung T S | 2010 | Ind Eng Chem Res2010，49，12： | 1 |
| 19 | Trajecto- ry and influencing factors of depressive symptoms in family care- givers before and after the death of terminally Ⅲ patients with cancer显示文摘 | Sing - Fang Ling Mei - Ling Chen Chung - Yi Li | 2013 | Oncology Nursing Society2013，40，1： | 1 |
| 20 | Flexible polymer photovoltaic devices prepared with inverted structures on metal foils 显示文摘 | Chen Fang Chung Wu Jyh Lih Lee Chia Ling | 2009 | IEEE Electron Device Letters2009，30，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员