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| 1 | A tailored,electronic textile conformable suit for large-scale spatiotemporal physiological sensing in vivo显示文摘The rapid advancement of electronic devices and fabrication technologies has further promoted the field of wearables and smart textiles.However,most of the current efforts in textile electronics focus on a single modality and cover a small area.Here,we have developed a tailored,electronic textile conformable suit(E-TeCS)to perform large-scale,multimodal physiological(temperature,heart rate,and respiration)sensing in vivo.This platform can be customized for various forms,sizes and functions using standard,accessible and high-throughput textile manufacturing and garment patterning techniques.Similar to a compression shirt,the soft and stretchable nature of the tailored E-TeCS allows intimate contact between electronics and the skin with a pressure value of around~25 mmHg,allowing for physical comfort and improved precision of sensor readings on skin.The E-TeCS can detect skin temperature with an accuracy of 0.1℃ and a precision of 0.01℃,as well as heart rate and respiration with a precision of 0.0012 m/s^(2) through mechano-acoustic inertial sensing.The knit textile electronics can be stretched up to 30%under 1000 cycles of stretching without significant degradation in mechanical and electrical performance.Experimental and theoretical investigations are conducted for each sensor modality along with performing the robustness of sensor-interconnects,washability,and breathability of the suit.Collective results suggest that our E-TeCS can simultaneously and wirelessly monitor 30 skin temperature nodes across the human body over an area of 1500 cm2,during seismocardiac events and respiration,as well as physical activity through inertial dynamics. | Irmandy Wicaksono Carson ITucker Tao Sun Cesar A.Guerrero Clare Liu Wesley M.Woo Eric J.Pence Canan Dagdeviren | 2020 | npj Flexible Electronics2020，4，1： | 4 |
| 2 | Association of cardiovascular system medications with cognitive function and dementia in older adults living in nursing homes in Australia显示文摘ObjectiveTo 在在检验生活和资源使用的质量的 17 所澳大利亚的疗养院的代表性的研究的 Australia.MethodsAs 部分住在疗养院的更老的成年人与认知功能和痴呆的诊断检验在心血管的系统药使用之间的协会,我们检验了在认知缺陷和心血管的药使用之间的协会(使用解剖治疗学的分类系统识别)用一般线性回归和逻辑 regressio 正在收到生活照顾的结束的人是包括的 excluded.ResultsParticipants 有一个平均数的 541 个居民 85.5 | Enwu Liu Suzanne M Dyer Lisa Kouladjian O'Donnell Rachel Milte Clare Bradley Stephanie L Harrison Emmanuel Gnanamanickam Craig Whitehead Maria Crotty | 2017 | Journal of Geriatric Cardiology2017，14，6： | 2 |
| 3 | Nanoparticulate TiO2 (B): an anode for lithium-ion batteries 显示文摘 | Yu Ren Liu Zheng Pourpoint Frederique Armstrong A Robert Grey Clare P Bruce Peter G | 2012 | Angewandte Chemie International Edition2012，51，9： | 1 |
| 4 | Crystallization force-a density functional theory concept for revealing intermolecular interactions and molecular packing in organic crystals显示文摘 | Li Tonglei Paul W Ayers Liu Shubin Matthew J Swadley Clare Aubrey-Medendorp | | 0，，： | 1 |
| 5 | Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of vohage-gated sodi- um channels 显示文摘 | Liu G Yarov-Yarovoy V Nobbs M Clare J J Scheuer T Cat -terall W A | 2003 | Neuropharmacology2003，44，： | 1 |
| 6 | Suppression of Wnt Signaling by Dkk1 Attenuates PTH-Mediated Stromal Cell Response and New Bone Formation显示文摘 | Jun Guo Minlin Liu Dehong Yang Mary L. Bouxsein Hiroaki Saito R.J. Sells Galvin Stuart A. Kuhstoss Clare C. Thomas Ernestina Schipani Roland Baron F. Richard Bringhurst Henry M. Kronenberg | 2010 | Cell Metabolism2010，，2： | 1 |
| 7 | Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression-and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner显示文摘Methamphetamine(Meth)abuse can cause serious mental disorders,including anxiety and depression.The gut microbiota is a crucial contributor to maintaining host mental health.Here,we aim to investigate if microbiota participate in Meth-induced mental disorders,and the potential mechanisms involved.Here,15 mg/kg Meth resulted in anxiety-and depression-like behaviors of mice successfully and suppressed the Sigma-1 receptor(SIGMAR1)/BDNF/TRKB pathway in the hippocampus.Mean-while,Meth impaired gut homeostasis by arousing the Toll-like receptor 4(TLR4)-related colonic inflammation,disturbing the gut microbiome and reducing the microbiota-derived short-chain fatty acids(SCFAs).Moreover,fecal microbiota from Meth-administrated mice mediated the colonic inflam-mation and reproduced anxiety-and depression-like behaviors in recipients.Further,SCFAs supple-mentation optimized Meth-induced microbial dysbiosis,ameliorated colonic inflammation,and repressed anxiety-and depression-like behaviors.Finally,Sigmarl knockout(Sigmar1^(-/-))repressed the BDNF/TRKB pathway and produced similar behavioral phenotypes with Meth exposure,and elim-inated the anti-anxiety and-depression effects of SCFAs.The activation of SIGMAR1 with fluvoxamine attenuated Meth-induced anxiety-and depression-like behaviors.Our findings indicated that gut microbiota-derived SCFAs could optimize gut homeostasis,and ameliorate Meth-induced mental disorders in a SIGMAR1-dependent manner.This study confirms the crucial role of microbiota in Methrelated mental disorders and provides a potential preemptive therapy. | Kaikai Zhang Lijian Chen Jianzheng Yang Jiali Liu Jiahao Li Yi Liu Xiuwen Li Long Chen Clare Hsu Jiahao Zeng Xiaoli Xie Qi Wang | 2023 | Acta Pharmaceutica Sinica B2023，13，12： | 0 |
| 8 | Blood:借助细胞外囊泡诊断儿童白血病潜力大显示文摘曼彻斯特大学的研究人员最近开发了一种新的白血病诊断检测方法,该方法的出现或将使得医生对一种常见的儿童白血病的诊断发生革命性变化。研究人员表示急性淋巴细胞白血病细胞能够产生和释放一种特殊的细胞外结构,可以在血液中进行追踪。该发现或对这种儿童白血病的诊断,药物输送和治疗有重要启示。相关研究结果发表在国际学术期刊Blood上。 | Suzanne M. Johnson Clare Dempsey Amy Chadwick Stephanie Harrison Jizhong Liu Yujun Di Owen J. McGinn Marco Fiorillo Federica Sotgia Michael P. Lisanti Mayur Parihar Shekhar Krishnan Vaskar Saha | 2017 | 现代生物医学进展2017，17，2： | 0 |
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