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2篇 您的检索式:作者名="Colin Reily"
    题名 作者 年代 出处 被引量
1Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1显示文摘Human adaptive immunity involves the production and secretion of antibodies by differentiated B cells(ie.,antibody-secreting cells,also called plasma cells)in response to antigens.These secreted antigen-specific antibodies are immunoglobulins that are present at substantial concentrations in blood,mucosal secretions,and breast milk.Structurally,human immunoglobulins consist of two identical heavy(H)chains and two identical light(L)chains that are connected by disulfide bridges to form a homodimer of heterodimers(ie.,H+Ll2).Each heterodimer consists of one H chain linked with one L chain,whereas the homodimer is formed by linking two H chains together.The genes for both the L and H chains are encoded by ligated gene segments that are genetically rearranged during V(D)J recombination,a process that endows each B cell with a unique receptor,giving rise to the enormous diversity of the B-cell antigen receptor repertoire.Jan Novak Matthew B.Renfrow R.Glenn King Colin Reily Todd J.Green 2023Cellular & Molecular Immunology2023,20,3:0
2Author Correction:Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1显示文摘In the sentence beginning'H chain genes are assembled from one functional variable(B),one diversity(D),and..'in this article,the text should have read'H chain genes are assembled from one functional variable(M),one diversity(D),and..'.Jan Novak Matthew B.Renfrow R.Glenn King Colin Reily Todd J.Green 2023Cellular & Molecular Immunology2023,20,3:0
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