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15篇 您的检索式:作者名="Jan Novak"
    题名 作者 年代 出处 被引量
1Glycosylation of IgA1 and pathogenesis of IgA nephropathy显示文摘Jan Novak Bruce Julian Jiri Mestecky Matthew Renfrow 2012Seminars in Immunopathology2012,,3:1
2Boron isotopic variations in tourmaline from metacarbonates and associated calc-silicate rocks from the Bohemian Massif: Constraints on boron recycling in the Variscan orogen显示文摘Various metacarbonate and associated calc-silicate rocks form minor but genetically significant components of the lithological units in the Bohemian Massif of the Variscan orogen in Central Europe.These rocks vary in terms of their lithostratigraphy,chemical composition and mineral assemblage(dolomite/calcite ratio,silicate abundance).Tourmaline is present in five paragenetic settings within the metacarbonate and calc-silicate units.TypeⅠcomprises individual,euhedral,prismatic grains and grain aggregates in a carbonate-dominant(calcite±dolomite)matrix poor in silicates.TypeⅡis characterized by euhedral to subhedral grains and coarse-to fine-grained aggregates in silicate-rich layers/nests within metacarbonate bodies whereas typeⅢoccurs as prismatic grains and aggregates at the contact zones between carbonate and associated silicate host rocks.TypeⅣis in veins crosscutting metacarbonate bodies,and typeⅣtourmaline occurs at the exocontacts of elbaite-subtype granitic pegmatite.Tourmaline from the different settings shows distinctive compositional features.Typical for typeⅠare Mg-rich compositions,with fluor-uvite>dravite>>magnesio-lucchesiite.Tourmalines from typeⅡsilicate-rich layers/nests are highly variable,corresponding to oxy-schorl,magnesio-foitite,Al-rich dravite and fluor-uvite.Typical for typeⅢtourmalines are Ca,Ti-bearing oxy-dravite compositions.The typeⅣveins feature dravite and fluor-uvite tourmaline compositions whereas typeⅤtourmaline is Li,F-rich dravite.Tourmaline is the only Bbearing phase in paragenetic typesⅠ-Ⅳ,where it is characterised by two principal ranges of B-isotope composition(δ^11B=-13‰to-9‰and-18‰to-14‰).These ranges correspond to regionally different units of the Moldanubian Zone.Thus,the Svratka Unit(Moldanubian Zone s.l.)contains only isotopically lighter tourmaline(δ^11B=-18‰to-14‰),whereas metacarbonates in the Poli?ka unit(Teplá-Barrandian Zone)and Olesnice unit(Moravicum of the Moravo-Silesian Zone)has exclusively isotopically heavier tourmaline(δ^11B=-9‰to-13‰).Tourmalines from metacarbonates in the Variegated Unit cover both ranges of isotope composition.The isotopically light end of the B isotope range may indicate the presence of continental evaporites within individual investigated areas.On the other hand,variations in the range of~8δ-units is consistent with the reported shift in B isotopic composition of metasedimentary rocks of the Bohemian Massif due to the prograde metamorphism from very-low grade to eclogite facies.In contrast to the metacarbonate-hosted settings,tourmaline of paragenetic type V from the exocontact of granitic pegmatites displays a significantly heavier range ofδ^11B(as low as-7.7‰to-0.6‰),which is attributed to partitioning of 10 B to cogenetic axinite and/or different B-signature of the source pegmatite containing tourmaline with heavyδ^11B signature.Lukas Krmcek Milan Novak Robert B.Trumbull Jan Cempirek Stanislav Houzar 2021Geoscience Frontiers2021,12,1:1
3Aberrant O -glycosylation and anti-glycan antibodies in an autoimmune disease IgA nephropathy and breast adenocarcinoma显示文摘Milada Stuchlová Horynová Milan Ra?ka Henrik Clausen Jan Novak 2013Cellular and Molecular Life Sciences2013,,5:1
4Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity显示文摘Suzuki Hitoshi Fan Run Zhang Zhixin Brown Rhubell Hall Stacy Julian Bruce A Chatham W Winn Suzuki Yusuke Wyatt Robert J Moldoveanu Zina Lee Jeannette Y Robinson James Tomana Milan Tomino Yasuhiko Mestecky Jiri Novak Jan 2009Journal of Clinical Investigation2009,,6:1
5IgA Glycosylation and IgA Immune Complexes in the Pathogenesis of IgA Nephropathy显示文摘Jan Novak Bruce A. Julian Milan Tomana Jiri Mestecky 2008Seminars in Nephrology2008,,1:1
6Progress in Molecular and Genetic Studies of IgA Nephropathy显示文摘Jan Novak Bruce A. Julian Milan Tomana Jiri Mestecky 2001Journal of Clinical Immunology2001,,5:1
7Wear and corrosion resistance of a plasma-nitrided PM tool steel alloyed with niobium 显示文摘Pavel Novak Dalibor Vojtech Jan Serak 2006Surrface &Coatings Technology2006,200,9:1
8Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy显示文摘McCarthy Douglas D Kujawa Julie Wilson Cheryl Papandile Adrian Poreci Urjana Porfilio Elisa A Ward Lesley Lawson Melissa A E Macpherson Andrew J McCoy Kathy D Pei York Novak Lea Lee Jeannette Y Julian Bruce A Novak Jan Ranger Ann Gommerman 2011Journal of Clinical Investigation2011,,10:1
9IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1显示文摘Suzuki Hitoshi Moldoveanu Zina Hall Stacy Brown Rhubell Vu Huong L Novak Lea Julian Bruce A Tomana Milan Wyatt Robert J Edberg Jeffrey C Alarcón Graciela S Kimberly Robert P Tomino Yasuhiko Mestecky Jiri Novak Jan 2008Journal of Clinical Investigation2008,,2:1
10The Pathophysiol- ogy of IgA Nephropathy 显示文摘Hitoshi Suzuki Krzysztof Kiryluk Jan Novak 2011J Am Soc Nephrol2011,22,:1
11Pathogenesis of Henoch-Sch?nlein purpura nephritis显示文摘Keith K. Lau Hitoshi Suzuki Jan Novak Robert J. Wyatt 2010Pediatric Nephrology2010,,1:1
12Mechanism and kinetics of the intermediary phase formation in Ti-A1 and Ti-A1-Si systems during reactive sintering 显示文摘Pavel Novak Jiri Kubasek Jan Serak 2009International Journal of Materials Research2009,100,3:1
13Genetic studies of IgA nephropathy: past, present, and future显示文摘Krzysztof Kiryluk Bruce A. Julian Robert J. Wyatt Francesco Scolari Hong Zhang Jan Novak Ali G. Gharavi 2010Pediatric Nephrology2010,,11:1
14Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1显示文摘Human adaptive immunity involves the production and secretion of antibodies by differentiated B cells(ie.,antibody-secreting cells,also called plasma cells)in response to antigens.These secreted antigen-specific antibodies are immunoglobulins that are present at substantial concentrations in blood,mucosal secretions,and breast milk.Structurally,human immunoglobulins consist of two identical heavy(H)chains and two identical light(L)chains that are connected by disulfide bridges to form a homodimer of heterodimers(ie.,H+Ll2).Each heterodimer consists of one H chain linked with one L chain,whereas the homodimer is formed by linking two H chains together.The genes for both the L and H chains are encoded by ligated gene segments that are genetically rearranged during V(D)J recombination,a process that endows each B cell with a unique receptor,giving rise to the enormous diversity of the B-cell antigen receptor repertoire.Jan Novak Matthew B.Renfrow R.Glenn King Colin Reily Todd J.Green 2023Cellular & Molecular Immunology2023,20,3:0
15Author Correction:Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1显示文摘In the sentence beginning'H chain genes are assembled from one functional variable(B),one diversity(D),and..'in this article,the text should have read'H chain genes are assembled from one functional variable(M),one diversity(D),and..'.Jan Novak Matthew B.Renfrow R.Glenn King Colin Reily Todd J.Green 2023Cellular & Molecular Immunology2023,20,3:0
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