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| 1 | MR imaging of neoplas tie central nervous system lesions: review and recommendations for current practice显示文摘 | Essig M Anzalone N Combs S E | 2012 | AJNR2012，33，5： | 1 |
| 2 | CCl4 induced toxicity in isolated hepatocytes: The importance of direct solvent injury 显示文摘 | Berger M L Bhatt N Combe B | 1986 | Hepatology1986，6，： | 1 |
| 3 | A cyclic AMP-and phorbol ester-inducible DNA element显示文摘 | Comb M Birnberg N C Seasholtz A | 1986 | Nature1986，323，6086： | 1 |
| 4 | Comparative evaluation of radiochemotherapy with temozolomide versus stan- dard - of- care postoperative radiation alone in patients with WHO grade Ⅲ astrocytie tumors 显示文摘 | Stephanie E Combs M N Lutz E | 2008 | Radiother Oncol2008，88，2： | 1 |
| 5 | MR imaging of neoplastic central nervous system lesions:Review and recommendations for current practice显示文摘 | Essig M Anzalone N Combs S E | 2012 | AJNR2012，33，5： | 1 |
| 6 | Periodic Mesoporous Organosilicas with Organic Groups Inside the Channel Walls显示文摘 | Asefa T Maclachian M J Combs N | 1999 | Nature1999，402，6764： | 1 |
| 7 | Combined effects of effects of pressure and temperature on enzyme stability 显示文摘 | Marie-Olive M N Athes V Combes D | 2000 | High Pressure Research2000，19，： | 1 |
| 8 | Stabilizing effect of polyhydric alcohols显示文摘 | Combes D Graber M Ye W N | 1990 | Annals of the New York Academy of Sciences1990，613，： | 1 |
| 9 | High rate of complete histopathological response in hepatocellular carcinoma patients after combined transarterial chemoembolization and stereotactic body radiation therapy显示文摘BACKGROUND Liver transplantation(LT)presents a curative treatment option in patients with early stage hepatocellular carcinoma(HCC)who are not eligible for resection or ablation therapy.Due to a risk of up 30%for waitlist drop-out upon tumor progression,bridging therapies are used to halt tumor growth.Transarterial chemoembolization(TACE)and less commonly stereotactic body radiation therapy(SBRT)or a combination of TACE and SBRT,are used as bridging therapies in LT.However,it remains unclear if one of those treatment options is superior.The analysis of explant livers after transplantation provides the unique opportunity to investigate treatment response by histopathology.AIM To analyze histopathological response to a combination of TACE and SBRT in HCC in comparison to TACE or SBRT alone.METHODS In this multicenter retrospective study,27 patients who received liver transplantation for HCC were analyzed.Patients received either TACE or SBRT alone,or a combination of TACE and SBRT as bridging therapy to liver transplantation.Liver explants of all patients who received at least one TACE and/or SBRT were analyzed for the presence of residual vital tumor tissue by histopathology to assess differences in treatment response to bridging therapies.Statistical analysis was performed using Fisher-Freeman-Halton exact test,Kruskal-Wallis and Mann-Whitney-U tests.RESULTS Fourteen patients received TACE only,four patients SBRT only,and nine patients a combination therapy of TACE and SBRT.There were no significant differences between groups regarding age,sex,etiology of underlying liver disease or number and size of tumor lesions.Strikingly,analysis of liver explants revealed that almost all patients in the TACE and SBRT combination group(8/9,89%)showed no residual vital tumor tissue by histopathology,whereas TACE or SBRT alone resulted in significantly lower rates of complete histopathological response(0/14,0%and 1/4,25%,respectively,P value<0.001).CONCLUSION Our data suggests that a combination of TACE and SBRT increases the rate of complete histopathological response compared to TACE or SBRT alone in bridging to liver transplantation. | Ulrike Bauer Sabine Gerum Falk Roeder Stefan Münch Stephanie E Combs Alexander B Philipp Enrico N De Toni Martha M Kirstein Arndt Vogel Carolin Mogler Bernhard Haller Jens Neumann Rickmer F Braren Marcus R Makowski Philipp Paprottka Markus Guba Fabian Geisler Roland M Schmid Andreas Umgelter Ursula Ehmer | 2021 | World Journal of Gastroenterology2021，27，24： | 1 |
| 10 | ABCAI gene deletion protects against cerebral malaria: potential pathogenic role of microparticles in neuropathology显示文摘 | Combes V Coltel N Alibert M | 2005 | Am J Pathol2005，166，1： | 1 |
| 11 | Genetic linkage map of Coffeacanephora: Effect of segregation distortion and analysis of recombination rate in male and female meiosis显示文摘 | Lashermes P Combes M C Prasash N S | 2001 | Genome2001，44，4： | 1 |
| 12 | Combined effects of pressure and temperature on enzyme stability 显示文摘 | Marie-Olive M N Athes V Combes D | 2000 | High Press Res2000，19，： | 1 |
| 13 | Character and spatial distribution of OH/H20 on the surface of the Moon seen by m3 on chandrayaan-1 显示文摘 | Pieters C M Goswami J N Clark R N Annadurai M Boardman J Buratti B Combe J-P Dyar M D Green R Head J W Hibbitts C Hicks M lsaacson P Klima R Kramer G Kumar S Livo E Lundeen S Malaret E McCord T Mustard J Nettles j Petm N Runyon C Staid M Sunshine J Taylor L A Tompkins S Varanasi P | 2009 | Science2009，326，5952： | 1 |
| 14 | Predicting the Effect of Proteolysis on Ruminal Crude Protein Degradation of Legume and Grass Silages Using Near-Infrared Reflectance Spectroscopy 显示文摘 | Hoffrnan P C BREHM N M COMBS D K | 1999 | Dairy Science1999，82，4： | 1 |
| 15 | Genetic linkage map of Coffea canephora : Effect of segregation distortion and analysis of recombination rate in male and female meiosis 显示文摘 | Lashermes P Combes M C Prakash N S | 2001 | Genome2001，44，4： | 1 |
| 16 | Acute pulmonary vein steno- sis after radiofrequency catheter ablation 显示文摘 | Combes N Boveda S Lapeyre M | 2009 | J Cardiovasc Electro- physiol2009，20，5： | 1 |
| 17 | Genetic linkage map of coffee canephora:Effect of segregation distortion and analysis of recombination rate in male and female meiosis显示文摘 | Lashermes P Combes M C Prakash N S Trouslot P Lorieux M Charrier A | | 0，，04： | 1 |
| 18 | A high-yield method for the extraction and purification of capsaicin显示文摘 | SASS N L ROUNSAVILL M COMBS B | 1977 | Journal of Agricultural and Food Chemistry1977，25，6： | 1 |
| 19 | Marine lipidbased liposomes increase in vivo FA bioavailability 显示文摘 | Cansell M Nacka F Combe N | 2003 | Lipids2003，38，5： | 1 |
| 20 | Analysis of genetic diversity in Indian robusta coffee genepool (Coffea eanephora) in comparison with a representalive core collection using SSRs and AFLPs显示文摘 | Prakash N S Combes M C Dussert S Naveen S Lashermes P | 2005 | Genet Resour Crop Evol2005，52，： | 1 |
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