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| 1 | Anemia in patients with high-risk acute coronary syndromes admitted to Intensive Cardiac Care Units显示文摘Background Little information exists about the role of anemia in patients with acute coronary syndromes(ACS)admitted to Intensive Cardiac Care Units(ICCU).The aim of this study was to assess the prevalence of anemia and its impact on management and outcomes in this clinical setting.Methods All consecutive patients admitted to eight different ICCUs with diagnosis of non-ST segment elevation ACS(NSTEACS)were prospectively included.Anemia was defined as hemoglobin<130 g/L in men and<120 g/L in women.The association between anemia and mortality or readmission at six months was assessed by the Cox regression method.Results A total of 629 patients were included.Mean age was 66.6 years.A total of 197 patients(31.3%)had anemia.Coronary angiography was performed in most patients(96.2%).Patients with anemia were significantly older,with a higher prevalence of comorbidities,poorer left ventricle ejection fraction and higher GRACE score values.Patients with anemia underwent less often coronary angiography,but underwent more often intraaortic counterpulsation,non-invasive mechanical ventilation and renal replacement therapies.Both ICCU and hospital stay were significantly longer in patients with anemia.Both the incidence of mortality(HR=3.36,95%CI:1.43–7.85,P=0.001)and the incidence of mortality/readmission were significantly higher in patients with anemia(HR=2.80,95%CI:2.03–3.86,P=0.001).After adjusting for confounders,the association between anemia and mortality/readmission remained significant(P=0.031).Conclusions Almost one of three NSTEACS patients admitted to ICCU had anemia.Most patients underwent coronary angiography.Anemia was independently associated to poorer outcomes at 6 months. | Victoria Lorente Jaime Aboal Cosme Garcia Jordi Sans-Rosello Antonia Sambola Rut Andrea Carlos Tomas Gil Bonet David Vinas Nabil el Ouaddi Santiago Montero Javier Cantalapiedra Margarida Pujol Isabel Hernandez Maria Perez-Rodriguez Isaac Llao Jose C Sanchez-Salado Miquel Gual Albert Ariza-Sole 无 | 2020 | Journal of Geriatric Cardiology2020，17，1： | 2 |
| 2 | Murine cytomegalovirus major immediate-early protein 3 interacts with cellular and vi- ral proteins in viral DNA replication compartments and is im- portant for early gene activation显示文摘 | Martinez F P Cosme R S C Tang Q | 2010 | J Gen Virol2010，91，11： | 1 |
| 3 | Optimization of honey-must preparation and alcoholic fermentation by Saccharomyces cerevisiae for mead production显示文摘 | MENDES-FERREIRA ~Cosme F BARBOSA C | 2010 | International Journal of Food Microbiology2010，144，： | 1 |
| 4 | Functional interaction of nuclear domain 10 and its components with cytomegalovirus after infections:cross-species host cells versus native cells显示文摘 | Cosme R C Martínez F P Tang Q | | 0，，04： | 1 |
| 5 | Evaluation of alpha1 -antitrypsin and the levels of mRNA expression of matrix metallopro-teinase-7,urokinase type plasminogen activator receptor and COX-2for the diagnosis of colorectal cancer显示文摘 | Bujanda L Sarasqueta C Cosme A | 2013 | PLoS One2013，8，51： | 1 |
| 6 | Fracture Strength of Endodontically Treated Teeth with Flared Root Canals and Restored with Different Post Systems显示文摘 | Maccari P C Cosme D C Oshima H M | | 0，，01： | 1 |
| 7 | A differential evolution approach for solving constrained rain-max optimization problems 显示文摘 | Gilberto A S Segundo A Renato A Krohling B Rodrigo C Cosme | 2012 | Expert Systems with Applications2012，39，13： | 1 |
| 8 | Application of Computer Aided Engineering in the Design of Heavy - Duty Truck Frames, International Truck & Bus Meeting & Exposition, Detroit, Michigan 显示文摘 | COSME C GHASEMI A GANDEVIA J | 1999 | November1999，，5： | 1 |
| 9 | A mild oxidativedecarboxylation of carbohy- drate acids显示文摘 | Cosme G F Concepcion C G Emesto S | 1997 | Tetrahedron Let-ters1997，38，： | 1 |
| 10 | Application of computer- aided engineering in the design of heavy- duty truck frames显示文摘 | Cosme C Ghasemi A Gandevia J | 1999 | SAE Transactions1999，108，10： | 1 |
| 11 | Abbreviated method for urea kinetic modeling in continuous ambulatory peritoneal dialysis patients显示文摘 | Francis D Rebeca S Cosme C | 1993 | Peritoneal Dialysis International1993，13，12： | 1 |
| 12 | Inferior alveolar nerve damage after lower third molar surgical extraction : a prospec- tive study of 1117 surgical extractions显示文摘 | EDWARD V C LEONARDO B A COSME G E | 2001 | Oral Surg Oral Med O- ral Pathol Oral Radiol Endod2001，92，4： | 1 |
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