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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Active vibration control using optimized modified acceleration feedback with Adaptive Line Enhancer for frequency tracking显示文摘 | Mahmoodi N Craft S Southward M J | | 0，，： | 1 |
| 3 | From T to B and back again:positive feedback in systemic autoimmune dis- ease 显示文摘 | Shlomchik M J Craft JE Mamula MJ | 2001 | Nat Rev Immunol2001，1，2： | 1 |
| 4 | From T to B and back again:positive feedback in systemic autoimmune disease显示文摘 | shlomchik M J craft J E Malnula M J | 2001 | Nat Rev Immunol2001，1，2： | 1 |
| 5 | Effects of sewage effluent and ethynyl oestradiol upon molecular markers of oestrogenic exposure, maturation and reproductive success in the sand goby (pomatoschistus minutus, pallas) 显示文摘 | Robinson C D Brown E Craft J A Davies I M Moffat C F Pirie D Robertson F Stagg R M Struthers S | 2003 | Aquatic Toxicology2003，62，2： | 1 |
| 6 | Regulation of T cell-dependent autoantibody production by a gammadelta T cell line derived from lupus-prone mice显示文摘 | OKADA M CRAFT J | 2002 | Cell Immunol2002，217，12： | 1 |
| 7 | Human amyloid beta-induced neuroinflammation is an early event in neurodegeneration显示文摘 | Craft J M Watterson D M Van Eldik L J | 2006 | Glia2006，53，5： | 1 |
| 8 | Cloning and developmental expression of the sucrose phosphate synthase gene from spinach 显示文摘 | Klein R R Crafts Brandner S J Salvueci M E | 1993 | Planta1993，190，4： | 1 |
| 9 | Resistance to Development of Collagen-induced Arthritis in C57BL/6 Mice is Due to a Defect in Secondary,but not in Primary,Immue Response显示文摘 | Pan M Kang I Craft J | 2004 | J Clin Immunol2004，24，： | 1 |
| 10 | Sex differences in pain and analgesia: the role of gonadal hormones显示文摘 | CRAFT R M MOGIL J S ALOISI A M | 2004 | Eur J Pain2004，8，5： | 1 |
| 11 | Comparing a domain-specific and global measure ofperfectionism in competitive female figure skaters显示文摘 | Dunn J G H Craft J M Causgrove D J | 2011 | Journal of Sport Behavior2011，34，1： | 1 |
| 12 | Action de Al2Cl6 surdivers chlorures et carbures显示文摘 | Friedel C Crafts J M | | Bull Soc Chim Fr0，27，： | 1 |
| 13 | Effects of salinity on denitrification and greenhouse gas production from laboratory-incubated tidal forest soils显示文摘 | Marton J M Herbert E R Craft C B | 2012 | Wetlands2012，32，2： | 1 |
| 14 | Carbon sequestration and nutrient (nitrogen, phosphorus) accumulation in river-dominated tidal marshes,Georgia, USA显示文摘 | LOOMIS M J CRAFT C B | 2010 | Soil Science Society of America Journal2010，74，： | 1 |
| 15 | Regulation of T cell-dependent autoantibody production by a gammadeha T cell line de- rived from lupus-prone mice显示文摘 | Fujii T Okada M Craft J | 2002 | Cell Immunol2002，217，12： | 1 |
| 16 | Using compiler optimization tech- niques to detect equivalent mutants显示文摘 | Offutt A J Craft W M | 1994 | Software Testing Verification and Reliability1994，4，3： | 1 |
| 17 | Anhedo-nia in postpartum rats 显示文摘 | NAVARRE B M LAGGART J D CRAFT R M | 2010 | Physiol Behav2010，99，1： | 1 |
| 18 | Absorption and malabsorption of glycine and glycine peptides in man 显示文摘 | Geddes D Hyde C W Wise I J Matthews D M | 1968 | Gut1968，，9： | 1 |
| 19 | Action de Al2Cl6 surlechlorure d'amyle 显示文摘 | Friedel C Crafts J M | | Bull Soc Chim France0，27，： | 1 |
| 20 | Frequency dependent pulse widths for CP 1133显示文摘 | Craft H D Comella J M | 1968 | Nature1968，220，： | 1 |
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