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| 1 | Targeting Tumor-Associated Macrophages by Anti-tumor Chinese Materia Medica显示文摘Tumor-associated macrophages(TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment. Chinese materia medica(CMM) is an important approach for treating cancer in China and in the Asian region. According to the theory of Chinese medicine(CM) and its practice, some prescriptions of CM regulate the body's internal environment possibly including the remodeling the tumor microenvironment(TME). Here we briefly summarize the pivotal effects of TAMs in shaping the TME and promoting tumorigenesis, invasion, metastasisand immunosuppression. Furthermore, we illustrate the effects and mechanisms of CMM targeting TAMs in antitumor therapy. Finally, we reveal the CMM's dual-regulatory and multi-targeting functions on regulating TAMs, and hopefully, provide the theoretical basis for CMM clinical practice related to cancer therapy. | PU Wei-ling SUN Li-kang GAO Xiu-mei Curzio Rüegg Muriel Cuendet Micheal O.Hottiger ZHOU Kun MIAO Lin ZHANG Yun-sha Margaret Gebauer | 2017 | Chinese Journal of Integrative Medicine2017，23，10： | 3 |
| 2 | The tumor microenvironment and its contribution to tumor evolution toward metastasis显示文摘 | Girieca Lorusso Curzio Rüegg | 2008 | Histochemistry and Cell Biology2008，，6： | 2 |
| 3 | Total Volatile Acids Content as a Quality Index of Irradiated Hake (Merluccius Merluc- cius Hubbsii) Fillets显示文摘 | Quaranta H O Curzio O A | 1983 | Food Chemistry1983，11，1： | 1 |
| 4 | An EfficientLow Cost Method for Gene Transfer to T Lymphocytes显示文摘 | Chicaybam L Sodre A L Curzio B A | 2013 | PLoS One2013，8，60： | 1 |
| 5 | Characterization of an accelerated-based neutron source for BNCT versus beam energy显示文摘 | AGOSTEO S CURZIO G NATH R | 2002 | Nucl Instrum Methods Phys Res Sect A2002，476，： | 1 |
| 6 | The tumor microenvironment and its contribution to tumor evolution toward metastasis显示文摘 | Girieca Lorusso Curzio Rüegg | 2008 | Histochemistry and Cell Biology2008，，6： | 1 |
| 7 | 显示文摘 | Martin I Veronique S Curzio R | 2000 | FEBS Letters2000，468，2： | 1 |
| 8 | Endothelial cell integrins and COX-2: mediators and therapeutic targets of tumor angiogenesis显示文摘 | Curzio Rüegg Olivier Dormond Agnese Mariotti | 2003 | BBA - Reviews on Cancer2003，，1： | 1 |
| 9 | Characterization of an accelerated-based neutron source for BNCT versus beam energy显示文摘 | Agosteo S Curzio G Nath R | 2002 | Nucl Instrum Meth2002，476，： | 1 |
| 10 | Possible role of aldehydic lipid peroxidation products as chemoattractants显示文摘 | Curzio M Esterbauer H Dianzani M U | 1987 | Int J Tissue React1987，9，： | 1 |
| 11 | Characterization of fiber/matrix interfaces in composites with a boron nitride matrix 显示文摘 | COFER C G ECONOMY J XU Y R ZANGVIL A CURZIO E L FERBER M K MORE K L | 1996 | Compos Sci Technol1996，56，： | 1 |
| 12 | Comparison of different ex- perimental techniques for determination of elastic properties of solids 显示文摘 | Radovic M Lara - Curzio E Riester L | 2004 | Materials Science and Engineering2004，368，： | 1 |
| 13 | Evidence for the involvement of endothelial cell integrin avβ3 in the disruption of the tumor vasculature induced by TNF and INFr显示文摘 | Curzio R Aysin Y Gregory B | 1998 | Nature Medicine1998，4，4： | 1 |
| 14 | Getting research into practice: develo- ping oral hygiene standards 显示文摘 | Curzio J McCowan M | 2000 | Br J Nurs2000，9，7： | 1 |
| 15 | The inte- grin antagonist cilengitide activates oLVI33, sisrupts VE-Cadherin lo- calization at cell junctions and enhances permeability in endothelial cells显示文摘 | Gian Carlo Alghisi Lionel Ponsonnet and Curzio R0 egg | 2009 | PLoS ONE2009，4，2： | 1 |
| 16 | Analysis of oxidation-assisted stress-rupture of continuous fiber- reinforced ceramic matrix composites at intermediate temperatures 显示文摘 | Lara- Curzio E | 1999 | Composites1999，30，： | 1 |
| 17 | A comparison of a 12-hour and 8-hour shift system显示文摘 | Gillespie A Curzio J | 1996 | Nurs Times1996，92，39： | 1 |
| 18 | Complete remission of nodular basal cell carcinoma after combined treatment with photodynamic therapy and imiquimod 5% cream显示文摘 | Devirgiliis V Panasiti V Curzio M | 2008 | Dermatol Online J2008，14，2： | 1 |
| 19 | The tumor microenvironment and its contribution to tumor evolution toward metastasis显示文摘 | Girieca Lorusso Curzio Rüegg | 2008 | Histochemistry and Cell Biology2008，，6： | 1 |
| 20 | Money, trust, and central banking显示文摘 | Curzio Giannini | 1995 | Journal of Economics and Business1995，，2： | 1 |
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