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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | 显示文摘 | Lima M D de Andrade M J Bergmann C P | 2008 | J Mater Chem2008，18，： | 1 |
| 3 | One-step RT-PCR protocols improve the rate of dengue diagnosis com- pared to two-step RT-PCR approaches显示文摘 | De Paula S O D Lima C D M Torres M P | 2004 | J Clin Virol2004，30，： | 1 |
| 4 | IgG fe receptors provide an alternative infection route for murine gamma-herpesvirus-68显示文摘 | Rosa G T Gillet L Smith C M de Lima B D Stevenson P G | 2007 | PLoS ONE2007，2，： | 1 |
| 5 | Knowledge about HPV and screening of cervical cancer among women from the metropolitan region of natal, brazil显示文摘 | Lima E G de Lima D B Miranda C A | 2013 | ISRN Obstet Gynecoh2013，2013，93： | 1 |
| 6 | lntestinal and pancreas enzyme activity of broilers exposed to thermal stress 显示文摘 | Routman K S l Yoshida L I Frizzas de Lima A C I et d | 2003 | Revista Brasileira de Ci-ncia Avlcola2003，5，1： | 1 |
| 7 | Heart rate monitoring in soccer:interest and limits during competitive match play and training, practical applica- tion显示文摘 | Alexandre D da Silva C D Hill-Haas S Wong del P Natali A J De Lima J R Bara Filho M G Matins J J Garcia E S Karim C | 2012 | J Strength Cond Res2012，26，10： | 1 |
| 8 | Heart rate monitoring in soccer: interest and limits during competitive match play and training, practical applica- tion显示文摘 | Alexandre D da Silva C D Hill-Haas S Wong del P Natali A J De Lima J R Bars Filho M G Matins J J Garcia E S Karim C | 2012 | J Strength C ond Res2012，26，10： | 1 |
| 9 | Synthesis, doc- king and in vitro activity of thiosemicarbazones, aminoacyl- thiosemi-carbazides and acyl-thiazolidones against Trypano- soma cruzi显示文摘 | Leite A C de Lima R S Moreira D R | 2006 | Bioorg Med Chem Lett2006，14，11： | 1 |
| 10 | Engineering properties of fiber reinforced cold asphalt mixes显示文摘 | Bueno B D W R da Silva D C de Lima | 2003 | Journal of Environmental Engineering2003，129，10： | 1 |
| 11 | DC conductivity and dielectric permittivity of collagen-chitosan films显示文摘 | Lima C G A de Oliveira R S Figueiro S D | 2006 | Materials Chemistry and Physics2006，99，： | 1 |
| 12 | Human papillomavirus genotype attribution in invasive cervical cancer:a retrospective cross-sectional worldwide study显示文摘 | de Sanjose S Quint WG Alemany L Geraets DT Klaustermeier JE Lloveras B Tous S Felix A Bravo LE Shin HR Vallejos CS de Ruiz PA Lima MA Guimera N Clavero O Alejo M Llombart-Bosch A Cheng-Yang C Tatti SA Kasamatsu E Iljazovic E Odida M Prado R Seoud M Grce M Usubutun A Jain A Suarez GA Lombardi LE Banjo A Menéndez C Domingo EJ Velasco J Nessa A Chichareon SC Qiao YL Lerma E Garland SM Sasagawa T Ferrera A Hammouda D Mariani L Pelayo A Steiner I Oliva E Meijer CJ AlJassar WF Cruz E Wright TC Puras A Llave CL Tzardi M Agorastos T Garcia-Barriola V Clavel C Ordi J Andújar M Castellsagué X Sánchez GI Nowakowsld AM Bornstein J Mu(n)oz N Bosch FX Retrospective International Survey and HPV Time Trends Study Group | 2010 | Lancet Oncol2010，11，11： | 1 |
| 13 | Embeded ato -m computer simulation of lattice distrotion and dislocatio -n core structure and mobility in Fe-Cr alloys显示文摘 | Frakas D Schon C G De Lima M S F | 1996 | Acta Mat-er1996，44，1： | 1 |
| 14 | Thl and Th2 cytokine immunomodulation by gangliosides in experimental autoimmune encephalomyelitis显示文摘 | Monteiro de Castro G Eduarda Zanin M Ventura-Oliveira D Aparecida Vilella C Ashimine R de Lima Zollner R | 2004 | CytoMne2004，26，： | 1 |
| 15 | EXAFS,X-ray diffraction and Mossbauer studies of an amorphous Fe60 Ti40alloy produced by mechanical alloying显示文摘 | De Lima J C Machado K D Drago V | 2003 | Journal of Non-Crystalline Solids2003，318，： | 1 |
| 16 | Synthesis,characterization and thermal decomposition of tin(Ⅳ) dithiocarbamate derivatives single source precursors for tin sulfide powders显示文摘 | Menezes D C de Lima G M Porto A O | 2004 | Polyhedron2004，23，： | 1 |
| 17 | Colono- scopic findings in asymptomatic people 显示文摘 | PETROIANU A ALBERTI L R DE LIMA D C | 2009 | Arq Gastroenterol2009，46，3： | 1 |
| 18 | Formation of γ-Cu67Al33 alloy by mechanical alloying显示文摘 | LIMA J C DE TRICHES D M SANTOS V H F DOS | 1999 | Journal of Alloys Compounds1999，282，： | 1 |
| 19 | Engineering Properties of Fiber Reinforced Cold Asphalt Mixes 显示文摘 | BUENOB S DA SILVA W R DE LIMA D C | 2003 | Journal of Environmental Engineering2003，129，10： | 1 |
| 20 | Importance of radiological studies by means of computed tomography for managing fractures of the tibial plateau 显示文摘 | de Lima Lopes C da Rocha Candido Filho CA de Lima E Silva TA et d | 2014 | Rev Bras Ortop2014，49，6： | 1 |
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