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| 1 | Fundamental rules to construct highly integrated organic nanowires as nanodevices显示文摘 | DE LIMA D B NERO J D | 2008 | J Comput Theor Nanosci2008，5，7： | 1 |
| 2 | IgG fe receptors provide an alternative infection route for murine gamma-herpesvirus-68显示文摘 | Rosa G T Gillet L Smith C M de Lima B D Stevenson P G | 2007 | PLoS ONE2007，2，： | 1 |
| 3 | Knowledge about HPV and screening of cervical cancer among women from the metropolitan region of natal, brazil显示文摘 | Lima E G de Lima D B Miranda C A | 2013 | ISRN Obstet Gynecoh2013，2013，93： | 1 |
| 4 | Multifractal IDW interpolationand fractal filtering method in environmental studies:an applicationon regional stream sediments of (Italy),Campania region显示文摘 | Lima A De Vivo B Cicchella D | 2003 | Applied Geochemistry2003，18，12： | 1 |
| 5 | Fundamental rules to construct highly integrated organic nanowires as nanodeviees显示文摘 | de Lima D B Nero J D | 2008 | J Comput Theor Nanosei2008，5，7： | 1 |
| 6 | Engineering properties of fiber reinforced cold asphalt mixes显示文摘 | Bueno B D W R da Silva D C de Lima | 2003 | Journal of Environmental Engineering2003，129，10： | 1 |
| 7 | Human papillomavirus genotype attribution in invasive cervical cancer:a retrospective cross-sectional worldwide study显示文摘 | de Sanjose S Quint WG Alemany L Geraets DT Klaustermeier JE Lloveras B Tous S Felix A Bravo LE Shin HR Vallejos CS de Ruiz PA Lima MA Guimera N Clavero O Alejo M Llombart-Bosch A Cheng-Yang C Tatti SA Kasamatsu E Iljazovic E Odida M Prado R Seoud M Grce M Usubutun A Jain A Suarez GA Lombardi LE Banjo A Menéndez C Domingo EJ Velasco J Nessa A Chichareon SC Qiao YL Lerma E Garland SM Sasagawa T Ferrera A Hammouda D Mariani L Pelayo A Steiner I Oliva E Meijer CJ AlJassar WF Cruz E Wright TC Puras A Llave CL Tzardi M Agorastos T Garcia-Barriola V Clavel C Ordi J Andújar M Castellsagué X Sánchez GI Nowakowsld AM Bornstein J Mu(n)oz N Bosch FX Retrospective International Survey and HPV Time Trends Study Group | 2010 | Lancet Oncol2010，11，11： | 1 |
| 8 | Interpolation methods for geochemical maps: A comparative study using arsenic data from European stream waters显示文摘 | Lima A Plant J A De Vivo B Tarvainen T Albanese S Cicchella D | 2008 | Geochem Explor Environ Anal2008，8，1： | 1 |
| 9 | Five Colletotrichum species are responsible for mango anthracnose in northeastern Brazil显示文摘 | LIMA N B BATISTA M V D A DE MORAIS JR M A | 2013 | Fungal Divers2013，61，1： | 1 |
| 10 | Multifraetal IDW interpolation and fractal filtering method in environ- mental studies: An application on regional stream sediments of (Italy), Campania region 显示文摘 | Lima A De Vivo B Cicchella D Cortini M Albanese S | 2003 | Applied Geo- chemistry2003，18，12： | 1 |
| 11 | Palladium and Platinum Concentration in Soils from the Napoli Metropolitan Area,ltaly:Possible Effects of Catalytic Exhausts显示文摘 | Cicchella D De Vivo B Lima A | 2003 | The Science of the Total Environment2003，308，1： | 1 |
| 12 | Hashimoto's encephalopathy: Systematic review of the literature and an additional case 显示文摘 | DE HOLANDA N C DE LIMA D D CAVALCANTI T B | 2011 | J Neuropsychiatry Clin Neurosci2011，23，4： | 1 |
| 13 | Engineering Properties of Fiber Reinforced Cold Asphalt Mixes显示文摘 | Bueno B D Silva W R da Lima D C de | 2003 | Journal of Environmental Engineering2003，129，10： | 1 |
| 14 | Multifractal IDW interpolation and ffactal filtering method in environmental studies: an application on regional stream sediments of (Italy), Campania region显示文摘 | Lima A De Vivo B Cicchella D | 2003 | Applied Geochemistry2003，18，12： | 1 |
| 15 | Background and baseline concentration values of dements harmful to human health in the volcanic soils of the metropolitan and provincial area of Napoli (Italy)显示文摘 | Cicchella D De Vivo B Lima A | | 0，，01： | 1 |
| 16 | Trypanosoma cruzi: Effect of the infection on the 20S proteasome in nonimmune cells显示文摘 | FARIA L O LIMA B D DE S C M | 2008 | Exp Parasitol2008，20，26： | 1 |
| 17 | Multifractal IDW in-terpolation and fractal filtering method in environmental stud-ies:An application on regional stream sediments of(Italy),Campania region 显示文摘 | Lima A De Vivo B Cicchella D | 2003 | Applied Geochemistry2003，18，12： | 1 |
| 18 | Real-world treatment patterns and disease control over one year in patients with inflammatory bowel disease in Brazil显示文摘BACKGROUND Crohn’s disease(CD)and ulcerative colitis(UC)are inflammatory bowel diseases(IBDs)with a remission-relapsing presentation and symptomatic exacerbations that have detrimental impacts on patient quality of life and are associated with a high cost burden,especially in patients with moderate-to-severe disease.The Real-world Data of Moderate-to-Severe Inflammatory Bowel Disease in Brazil(RISE BR)study was a noninterventional study designed to evaluate disease control,treatment patterns,disease burden and health-related quality of life in patients with moderate-to-severe active IBD.We report findings from the prospective follow-up phase of the RISE BR study in patients with active UC or CD.AIM To describe the 12-mo disease evolution and treatment patterns among patients with active moderate-to-severe IBD in Brazil.METHODS This was a prospective,noninterventional study of adult patients with active Crohn’s disease(CD:Harvey-Bradshaw Index≥8,CD Activity Index≥220),inadequate CD control(i.e.,calprotectin>200μg/g or colonoscopy previous results),or active ulcerative colitis(UC:Partial Mayo score≥5).Enrollment occurred in 14 centers from October 2016 to February 2017.The proportion of active IBD patients after 9-12 mo of follow-up,Kaplan-Meier estimates of the time to mild or no activity and a summary of treatment initiation,discontinuation and dose changes were examined.RESULTS The study included 118 CD and 36 UC patients,with mean±SD ages of 43.3±12.6 and 44.9±16.5 years,respectively.The most frequent drug classes at index were biologics for CD(62.7%)and 5-aminosalicylate derivates for UC patients(91.7%).During follow-up,65.3%of CD and 86.1%of UC patients initiated a new treatment at least once.Discontinuations/dose changes occurred in 68.1%of CD patients[median 2.0(IQR:2-5)]and 94.3%of UC patients[median 4.0(IQR:3-7)].On average,CD and UC patients had 4.4±2.6 and 5.0±3.3 outpatient visits,respectively.The median time to first mild or no activity was 319(IQR:239-358)d for CD and 320(IQR:288-358)d for UC patients.At 9-12 mo,22.0%of CD and 20.0%of UC patients had active disease.CONCLUSION Although a marked proportion of active IBD patients achieved disease control within one year,the considerable time to achieve this outcome represents an unmet medical need of the current standard of care in a Brazilian real-world setting. | Ligia Yukie Sassaki Sender J Miszputen Roberto Luiz Kaiser Junior Wilson R Catapani Mauro Bafutto António S Scotton Cyrla Zaltman Julio Pinheiro Baima Hagata S Ramos Mikaell Alexandre Gouvea Faria Carolina D Gonçalves Isabella Miranda Guimaraes Cristina Flores Heda M B S Amarante Rodrigo Bremer Nones JoséMiguel Luz Parente Murilo Moura Lima Júlio Maria Chebli Maria de Lourdes Abreu Ferrari Julia F Campos Maria G P Sanna Odery Ramos Rogério Serafim Parra Jose J R da Rocha Omar Feres Marley R Feitosa Rosana Fusaro Caratin Juliana Tosta Senra Genoile Oliveira Santana | 2021 | World Journal of Gastroenterology2021，27，23： | 0 |
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