| 5 | Preparation and Quality Evaluation of Toltrazuril Nanoemulsion显示文摘To determine the prescription and preparation method of toltrazuril nanoemulsion,we selected liquid paraffin,ethyl acetate,soybean oil,IPM and oleic acid as the oil phases,while RH-40,EL-40,OP-10,Tween-80 and Span-80 were the surfactants,and alcohol,1,2-ropanediol,ispropanl,glycerol and PEG-400 were the co-surfactants. The best prescription was acquired through pseudo-ternary phase diagrams. The result showed that ethyl acetate,Tween-80 and 1,2-propanediol could facilitate the formation of nanoemulsion. The optimum prescription was surfactant∶co-surfactant∶oil phase∶water phase = 2∶1∶2∶5,with the solubilizer of 10%. This prescription can prepare stable toltrazuril nanoemulsion. | Zhang Zhimei Deng Xuming Shen Zhiqiang Guo Shijin Fu Shijun | 2015 | Animal Husbandry and Feed Science2015，7，5： | 0 |
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