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| 1 | TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy显示文摘 | Chengyan Wang Xuming Tang Xiaomeng Sun Zhenchuan Miao Yaxin Lv Yanlei Yang Huidan Zhang Pengbo Zhang Yang Liu LiyingDu Yang Gao Ming Yin Mingxiao Ding Hongkui Deng | 2012 | Cell Research2012，22，1： | 17 |
| 2 | Enhanced ion conductivity and electrode–electrolyte interphase stability of porous Si anodes enabled by silicon nitride nanocoating for high-performance Li-ion batteries显示文摘Silicon (Si) is a promising anode material for next-generation high-energy lithium-ion batteries (LIBs) due to its high capacity.However,the large volumetric expansion,poor ion conductivity and unstable solid electrolyte interface (SEI) lead to rapid capacity fading and low rate performance.Herein,we report Si nitride (SiN) comprising stoichiometric Si_(3)N_(4) and Li-active anazotic SiN_(x) coated porous Si (p-Si@SiN)for high-performance anodes in LIBs.The ant-nest-like porous Si consisting of 3D interconnected Si nanoligaments and bicontinuous nanopores prevents pulverization and accommodates volume expansion during cycling.The Si_(3)N_(4) offers mechanically protective coating to endow highly structural integrity and inhibit superfluous formation of SEI.The fast ion conducting Li_(3)N generated in situ from lithiation of active SiN_(x) facilitates Li ion transport.Consequently,the p-Si@SiN anode has appealing electrochemical properties such as a high capacity of 2180 mAh g^(-1)at 0.5 A g^(-1) with 84%capacity retention after 200cycles and excellent rate capacity with discharge capacity of 721 mAh g^(-1) after 500 cycles at 5.0 A g^(-1).This work provides insights into the rational design of active/inactive nanocoating on Si-based anode materials for fast-charging and highly stable LIBs. | Shixiong Mei Siguang Guo Ben Xiang Jiaguo Deng Jijiang Fu Xuming Zhang Yang Zheng Biao Gao Paul K Chu Kaifu Huo | 2022 | Journal of Energy Chemistry2022，31，6： | 2 |
| 3 | ER?α36?mediated gastric cancer cell proliferation via the c?Src pathway显示文摘 | Xuming Wang Hao Deng Feng Zou Zhenqi Fu Ying Chen Zhaoyi Wang Lijiang Liu | 2013 | Oncology Letters2013，，2： | 1 |
| 4 | Involvement of ER ‐α36 in the malignant growth of gastric carcinoma cells is associated with GRP 94 overexpression显示文摘 | Zhengqi Fu Hao Deng Xuming Wang Xiuping Yang Zhaoyi Wang Lijiang Liu | 2013 | Histopathology2013，，3： | 1 |
| 5 | Short-term roxithromycin treatment attenuates airway inflammation via MAPK/NF-κB activation in a mouse model of allergic asthma显示文摘 | Xinxin Ci Xiao Chu Xue Xu Hongyu Li Xuming Deng | 2012 | Inflammation Research2012，，7： | 1 |
| 6 | Enhanced atherothrombotic formation after oxidative injury by FeCl 3 to the common carotid artery in severe combined hyperlipidemic mice显示文摘 | Xunde Xian Yu Ding Ling Zhang Yanan Wang Michael A. McNutt Colin Ross Michael R. Hayden Xuming Deng George Liu | 2009 | Biochemical and Biophysical Research Communications2009，，4： | 1 |
| 7 | New geo-physical techniques for oil and gas reservoir evaluation in east-ern China显示文摘 | Deng Zhiwen Zou Xuefeng Bai Xuming | 2007 | The Leading Edge2007，26，3： | 1 |
| 8 | Hesperidin Suppresses Ovalbumin-Induced Airway Inflammation in a Mouse Allergic Asthma Model显示文摘 | Dajun Wei Xinxin Ci Xiao Chu Miaomiao Wei Shucheng Hua Xuming Deng | 2012 | Inflammation2012，，1： | 1 |
| 9 | The in vitro immunomodulatory activity of a polysaccharide isolated from Kadsura marmorata显示文摘 | Hongjun Wang Xuming Deng Tiezhong Zhou Chunhua Wang Yanjie Hou Hong Jiang Guangliang Liu | 2013 | Carbohydrate Polymers2013，，2： | 1 |
| 10 | Preparation and Quality Evaluation of Toltrazuril Nanoemulsion显示文摘To determine the prescription and preparation method of toltrazuril nanoemulsion,we selected liquid paraffin,ethyl acetate,soybean oil,IPM and oleic acid as the oil phases,while RH-40,EL-40,OP-10,Tween-80 and Span-80 were the surfactants,and alcohol,1,2-ropanediol,ispropanl,glycerol and PEG-400 were the co-surfactants. The best prescription was acquired through pseudo-ternary phase diagrams. The result showed that ethyl acetate,Tween-80 and 1,2-propanediol could facilitate the formation of nanoemulsion. The optimum prescription was surfactant∶co-surfactant∶oil phase∶water phase = 2∶1∶2∶5,with the solubilizer of 10%. This prescription can prepare stable toltrazuril nanoemulsion. | Zhang Zhimei Deng Xuming Shen Zhiqiang Guo Shijin Fu Shijun | 2015 | Animal Husbandry and Feed Science2015，7，5： | 0 |
| 11 | Discharge area segmentation of power equipment in UV image based on GVF snake model显示文摘The dynamic transmission characteristics and the sensitivities of the three stage idler gear system of the new NC power turret are studied in the paper. Considering the strongly nonlinear factors such as the periodically time-varying mesh stiffness, the nonlinear tooth backlash, the lump-parameter model of the gear system is developed with one rotational and two translational freedoms of each gear. The eigen-values and eigenvectors are derived and analyzed on the basis of the real modal theory. The sensitivities of natural frequencies to design parameters including supporting and meshing stiffnesses, gear masses, and moments of inertia by the direct differential method are also calculated. The results show the quantitative and qualitative impact of the parameters to the natural characteristics of the gear system. Furthermore, the periodic steady state solutions are obtained by the numerical approach based on the nonlinear model. These results are employed to gain insights into the primary controlling parameters, to forecast the severity of the dynamic response, and to assess the acceptability of the gear design. | He Zhenhua Deng Wei Li Lianlian Huang Wenwu Wang Wei Liu Xuming | 2014 | 仪器仪表学报2014，35，S1： | 0 |
| 12 | Discovery of Kaempferol,a Novel ADAM10 Inhibitor,as a Potential Treatment for Staphylococcus aureus Infection显示文摘Host-directed therapy(HDT)is an emerging novel approach for treating multidrug-resistant Staphylococcus aureus(S.aureus)infection.Functioning as the indispensable specific cellular receptor for a-toxin(Hla),a-disintegrin and metalloproteinase 10(ADAM10)is exploited to accelerate S.aureus infection through diverse mechanisms.The extraordinary contribution of ADAM10 to S.aureus pathogenesis renders it an attractive HDT target for combating S.aureus infection.Our study is the first to demonstrate the indispensable role of ADAM10 in S.aureus-induced necroptosis,and it enhances our knowledge of the role of ADAM10 in S.aureus infection.Using a fluorogenic substrate assay,we further identified kaempferol as a potent ADAM10 inhibitor that effectively protected mice from S.aureus infection by suppressing Hla-mediated barrier disruption and necroptosis.Collectively,our work presents a novel hostdirected therapeutic strategy for using the promising candidate kaempferol to treat S.aureus infection and other diseases relevant to the disordered upregulation of ADAM10. | Tingting Wang Jianfeng Wang Xiangzhu Xu Fan Jiang Hongfa Lv Qinghui Qi Can Zhang Qianghua Lv Xuming Deng | 2023 | Engineering2023，，9： | 0 |
| 13 | Comparative Genomics Reveals Evolutionary Drivers of Sessile Life and Left-right Shell Asymmetry in Bivalves显示文摘Bivalves are species-rich mollusks with prominent protective roles in coastal ecosystems.Across these ancient lineages,colony-founding larvae anchor themselves either by byssus production or by cemented attachment.The latter mode of sessile life is strongly molded by left-right shell asymmetry during larval development of Ostreoida oysters such as Crassostrea hongkongensis.Here,we sequenced the genome of C.hongkongensis in high resolution and compared it to reference bivalve genomes to unveil genomic determinants driving cemented attachment and shell asymmetry.Importantly,loss of the homeobox gene Antennapedia(Antp)and broad expansion of lineagespecific extracellular gene families are implicated in a shift from byssal to cemented attachment in bivalves.Comparative transcriptomic analysis shows a conspicuous divergence between leftright asymmetrical C.hongkongensis and symmetrical Pinctada fucata in their expression profiles.Especially,a couple of orthologous transcription factor genes and lineage-specific shell-related gene families including that encoding tyrosinases are elevated,and may cooperatively govern asymmetrical shell formation in Ostreoida oysters. | Yang Zhang Fan Mao Shu Xiao Haiyan Yu Zhiming Xiang Fei Xu Jun Li Lili Wang Yuanyan Xiong Mengqiu Chen Yongbo Bao Yuewen Deng Quan Huo Lvping Zhang Wenguang Liu Xuming Li Haitao Ma Yuehuan Zhang Xiyu Mu Min Liu Hongkun Zheng Nai-Kei Wong Ziniu Yu | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 0 |
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