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2篇 您的检索式：作者名="DENG Yuanying"

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		题名	作者	年代	出处	被引量
	1	Neo- natal chlorpyrifos exposure induces loss of dopaminergie neu- rons in young adult rats 显示文摘	ZHANG Jle DAI Hongmei DENG Yuanying	2015	Toxicology2015，336，：	1
	2	Automated screening of primary cell-based aptamers for targeting and therapy of pancreatic cancer显示文摘Although it has been developed for many years, nucleic acid aptamer screening technology still fails to be widely used, a considerable part of it is due to the variability of tumor cell morphology, which leads to the use of immortalized cell lines in the laboratory to screen nucleic acid aptamers for recognition ability of tumor cells in the diseased body.To address this, primary cells that can be stably passaged were isolated and extracted from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice in this study.Next, an automated screening instrument for nucleic acid aptamers developed autonomously by our group was used to perform efficient aptamer screening using a limited number of cells, and the obtained nucleic acid aptamers were affinity verified at the cellular level.Finally, to answer the question of the cell growth environment difference on the recognition ability of nucleic acid aptamers, we verified its targeting ability to tumors in vivo on a nude mice xenograft tumor model, and further used a common antitumor drug doxorubicin combined with nucleic acid aptamers to verify the drug loading ability of this aptamer combined with the targeting therapeutic ability.	Zhukang Guo Baijiang Jin Yile Fang Lian Jin Song Li Yan Deng Zhu Chen Hui Chen Yuanying Zhang Rabia Usman Nongyue He	2024	Chinese Chemical Letters2024，35，2：	0

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