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| 1 | Evolution of indications and results of liver transplantation in Europe. A report from the European Liver Transplant Registry (ELTR)显示文摘 | René Adam Vincent Karam Valérie Delvart John O’Grady Darius Mirza Jurgen Klempnauer Denis Castaing Peter Neuhaus Neville Jamieson Mauro Salizzoni Stephen Pollard Jan Lerut Andreas Paul Juan Carlos Garcia-Valdecasas Fernando San Juan Rodríguez Andrew Burro | 2012 | Journal of Hepatology2012，，3： | 6 |
| 2 | Contribution of functional KIR3DL1 to ankylosing spondylitis显示文摘Increasing evidence points to a role for killer immunoglobulin-like receptors(KIRs)in the development of autoimmune diseases.In particular,a positive association of KIR3DS1(activating receptor)and a negative association of KIR3DL1(inhibitory receptor)alleles with ankylosing spondylitis(AS)have been reported by several groups.However,none of the studies analyzed these associations in the context of functionality of polymorphic KIR3DL1.To better understand how the KIR3DL1/3DS1 genes determine susceptibility to AS,we analyzed the frequencies of alleles and genotypes encoding functional(KIR3DL1*F)and non-functional(KIR3DL1*004)receptors.We genotyped 83 AS patients and 107 human leukocyte antigen(HLA)-B27-positive healthy controls from the Russian Caucasian population using a two-stage sequence-specific primer PCR,which distinguishes KIR3DS1,KIR3DL1*F and KIR3DL1*004 alleles.For the patients carrying two functional KIR3DL1 alleles,those alleles were additionally genotyped to identify KIR3DL1*005 and KIR3DL1*007 alleles,which are functional but are expressed at low levels.KIR3DL1 was negatively associated with AS at the expense of KIR3DL1*F but not of KIR3DL1*004.This finding indicates that the inhibitory KIR3DL1 receptor protects against the development of AS and is not simply a passive counterpart of the segregating KIR3DS1 allele encoding the activating receptor.However,analysis of genotype frequencies indicates that the presence of KIR3DS1 is a more important factor for AS susceptibility than the absence of KIR3DL1*F.The activation of either natural killer(NK)or T cells via the KIR3DS1 receptor can be one of the critical events in AS development,while the presence of the functional KIR3DL1 receptor has a protective effect.Nevertheless,even individuals with a genotype that carried two inhibitory KIR3DL1 alleles expressed at high levels could develop AS. | Ivan V Zvyagin Ilgar Z Mamedov Olga V Britanova Dmitriy B Staroverov Evgeni L Nasonov Anna G Bochkova Anna V Chkalina Alexei A Kotlobay Dmitriy O Korostin Denis V Rebrikov Sergey Lukyanov Yuri B Lebedev Dmitriy M Chudakov | 2010 | Cellular & Molecular Immunology2010，7，6： | 5 |
| 3 | 老年人处方遗漏筛查工具第2版(中文版)显示文摘近年来我国老年人口数量迅速增加,2013年老年人口突破2亿大关。老年人常伴有多种疾病且同时服用多种药物,容易出现药物相互作用和药物不良反应,所以老年人用药问题是医务人员关注的重点。老年人不适当用药问题主要包括两个方面:老年人需要避免使用的药物和老年人需要使用而未使用的药物。 | Denis O'Mahony David O'Sullivan Stephen Byrne Marie Noelle O'Connor Cristin Ryan Paul Gallagher 侯凯旋 邢晓璇 闫素英 | 2017 | 药物不良反应杂志2017，19，5： | 4 |
| 4 | Density functional investigation of atmospheric sulfur chemistry Ⅱ: The heat of formation of the XSO2 radical X=H, CH3 显示文摘 | Denis P A Ventura O N | 2001 | Chem Phys Lett2001，344，： | 2 |
| 5 | Evolution of liver transplantation in Europe: Report of the European Liver Transplant Registry显示文摘 | René Adam Paul McMaster John G. O’Grady Denis Castaing Jurgen L. Klempnauer Neville Jamieson Peter Neuhaus Jan Lerut Mauro Salizzoni Stephen Pollard Ferdinand Muhlbacher Xavier Rogiers Juan Carlos Garcia Valdecasas Joaquin Berenguer Daniel Jaeck Enrique M | 2003 | Liver Transplantation2003，，12： | 2 |
| 6 | A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study显示文摘 | Michael J. Proctor David S. Morrison Dinesh Talwar Steven M. Balmer Colin D. Fletcher Denis St.J. O’Reilly Alan K. Foulis Paul G. Horgan Donald C. McMillan | 2011 | European Journal of Cancer2011，，17： | 2 |
| 7 | Evolution of liver transplantation in Europe: Report of the European Liver Transplant Registry显示文摘 | René Adam Paul McMaster John G. O’Grady Denis Castaing Jurgen L. Klempnauer Neville Jamieson Peter Neuhaus Jan Lerut Mauro Salizzoni Stephen Pollard Ferdinand Muhlbacher Xavier Rogiers Juan Carlos Garcia Valdecasas Joaquin Berenguer Daniel Jaeck Enrique M | 2003 | Liver Transplantation2003，，12： | 2 |
| 8 | Immunogenicity and protective efficacy of a tuberculosis DNA vaccine 显示文摘 | Huygen K Content J Denis O | 1996 | Nat Med1996，2，8： | 1 |
| 9 | Esophageal cancer:outcome according to therapeutic strategy显示文摘 | Rousseau D Capitain O Denis F | 2013 | Cancer Radiother2013，17，1： | 1 |
| 10 | Apparent diffusion coefficient as an MR imaging biomarker of low-risk ductal carcinoma in situ: a pilot study 显示文摘 | Mami L Denis LB Ryosuke O | 2011 | Radiology2011，260，2： | 1 |
| 11 | Cellular physiology of cholesterol efflux in vascular endothelial cells 显示文摘 | O'Connell B J Denis M Genest J | 2004 | Circulation2004，110，18： | 1 |
| 12 | In vitro activities of ceftobipm- le, tigecycline, daptomycin, and 19 other antimicrobials against methi- cillin - resistant staphylococcus aureus strains from a national survey of belgian hospitals显示文摘 | Denis O Deplano A Nonhoff C | 2006 | Antimicrob Agents Chemother2006，50，8： | 1 |
| 13 | Polyhedron 显示文摘 | Michael Devereux Denis O' Shea Mark O' Connor Helen Grehan Gavin Connor | 2007 | 26:4073-40842007，26，： | 1 |
| 14 | Immunogenicity and protective efficacy of a tuberculosis DNA vaccine显示文摘 | HUYGEN K CONTENT J DENIS O | 1996 | Nat Med1996，2，8： | 1 |
| 15 | Emergence of vancomycin2intennediate S tap hy loeoccns aureus in a Belgian hospital : microbiological and clinical features 显示文摘 | Denis O Nonhoff C Byl B | 2002 | J Antimierob Chemother2002，50，3： | 1 |
| 16 | In vitro activities of cefto biprole,tigeeycline,daptomycin,and19other antimicrobials against methicillin-resistant staphylococcus strains from a national survey of belgian hospitals显示文摘 | Denis O Deplano A Nonhoff C | 2006 | Antimicrob Agents Chemother2006，50，8： | 1 |
| 17 | TuberculosisDNA vaccine encoding Ag85A is immunogenic and protec-tive when administered by intramuscular needle injectionbut not by epidermal gene gun bombardment显示文摘 | Tanghe A Denis O Lambercht B | 2000 | Infectionand Immunity2000，68，7： | 1 |
| 18 | Immunogenicity and protective efficacy of a tuberculosis DNA vaccine显示文摘 | HUYGEN K CONTENT J DENIS O | 1996 | Nature Medicine1996，2，8： | 1 |
| 19 | Controlled evaluation of the IDI-MRSA assay for detection of colonization by methicillin-resistant Staphylococcus aureus in diverse mucocutaneous specimens显示文摘 | San ND Denis O Gasasira MF Mendon(c)a RD Nonhoff C Struelens MJ | | Journal of Clinical Microbiology0，，： | 1 |
| 20 | Effect of an active packaging with citrus extract on lipid oxidation and sensory quality of cooked turkey meat显示文摘 | Claudia Contini Rocío álvarez Michael O’Sullivan Denis P. Dowling Sean óg Gargan Frank J. Monahan | 2014 | Meat Science2014，，3： | 1 |
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