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| 1 | Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock显示文摘The mixed venous-to-arterial carbon dioxide(CO_2)tension difference[P(v-a) CO_2]is the difference between carbon dioxide tension(PCO_2) in mixed venous blood(sampled from a pulmonary artery catheter) and the PCO_2 in arterial blood.P(v-a) CO_2 depends on the cardiac output and the global CO_2 production,and on the complex relationship between PCO_2 and CO_2 content.Experimental and clinical studies support the evidence that P(v-a) CO_2 cannot serve as an indicator of tissue hypoxia,and should be regarded as an indicator of the adequacy of venous blood to wash out the total CO_2generated by the peripheral tissues.P(v-a) CO_2 can be replaced by the central venous-to-arterial CO_2 difference(△PCO_2),which is calculated from simultaneous sampling of central venous blood from a central vein catheter and arterial blood and,therefore,more easy to obtain at the bedside.Determining the △PCO_2 during the resuscitation of septic shock patients might be useful when deciding when to continue resuscitation despite a central venous oxygen saturation(SCVO_2) > 70%associated with elevated blood lactate levels.Because high blood lactate levels is not a discriminatory factor in determining the source of that stress,an increased △PCO_2(> 6 mmHg)could be used to identify patients who still remain inadequately resuscitated.Monitoring the △PCO_2 from the beginning of the reanimation of septic shock patients might be a valuable means to evaluate the adequacy of cardiac output in tissue perfusion and,thus,guiding the therapy.In this respect,it can aid to titrate inotropes to adjust oxygen delivery to CO_2 production,or to choose between hemoglobin correction or fluid/inotrope infusion in patients with a too low ScvO_2 related to metabolic demand.The combination of P(v-a) CO_2 or △PCO_2 with oxygen-derived parameters through the calculation of the P(v-a) CO_2 or △PCO_2/arteriovenous oxygen content difference ratio can detect the presence of global anaerobic metabolism. | Jihad Mallat Malcolm Lemyze Laurent Tronchon Beno?t Vallet Didier Thevenin | 2016 | World Journal of Critical Care Medicine2016，5，1： | 25 |
| 2 | Effect of Cyclosporine on Left Ventricular Remodeling After Reperfused Myocardial Infarction显示文摘 | Nathan Mewton Pierre Croisille Gerald Gahide Gilles Rioufol Eric Bonnefoy Ingrid Sanchez Thien Tri Cung Catherine Sportouch Denis Angoulvant Gérard Finet Xavier André-Fou?t Geneviève Derumeaux Christophe Piot Hélène Vernhet Didier Revel Michel Ovize | 2010 | Journal of the American College of Cardiology2010，，12： | 2 |
| 3 | 查看详情显示文摘 | Schuchardt K L Didier B T Elsethagen T Sun L Gurumoorthi V Chase J Li J Windus T L | | 0，，3： | 1 |
| 4 | Ozone and water deficit reduced growth of Aleppo pine seedlings显示文摘 | Didier L T Sirkku M | 2003 | Plant Physiology and Biochemistry2003，41，： | 1 |
| 5 | Existence of Global Weak Solutions for a 2D Viscous Shallow Water Equations and Convergence to the Quasi-Geostrophic Model显示文摘 | Didier Bresch Beno?t Desjardins | 2003 | Communications in Mathematical Physics (-)2003，，1： | 1 |
| 6 | Hyperthyroidism with severe intra-hepatic cholestasis 显示文摘 | ViaUard F Antoine T Didier N | 1999 | Digestive Diseases and Sciences1999，4，10： | 1 |
| 7 | Synthesis and character- ization of Zn/A1 and Pt/Zn/A1 layered double hydrox- ides obtained by the sol-gel method显示文摘 | Didier T Olivier L Bernard C | 2005 | Microporous and Mesoporous Materials2005，80，13： | 1 |
| 8 | Gross capital flows: dynamics and crises显示文摘 | Broner F T Didier A Erce | 2013 | Journal of Monetary Economics2013，60，1： | 1 |
| 9 | Calcium/calmodulin-mediated regulation of plant immunity显示文摘 | Cécilia Cheval Didier Aldon Jean-Philippe Galaud Beno?t Ranty | 2013 | BBA - Molecular Cell Research2013，，7： | 1 |
| 10 | Ethnopharmacology and bioinformatic combination for leads discovery: application to phospholipase A(2) inhibitors 显示文摘 | Bernard P Scior T Didier B | 2001 | Phytochemistry2001，58，6： | 1 |
| 11 | Safety of Laparoscopic Approach for Acute Cholecystitis: Retrospective Study of 609 Cases显示文摘 | Beno?t Navez Didier Mutter Yves Russier Michel Vix Faek Jamali David Lipski Emmanuel Cambier Pierre Guiot Jo?l Leroy Jacques Marescaux | 2001 | World Journal of Surgery2001，，10： | 1 |
| 12 | Ethnopharmacology and bioinformatic combination for leads discovery: application to phospholipase A (2) inhibitors显示文摘 | Bernard P Seior T Didier B etal | 2001 | Phytochemistry2001，58，6： | 1 |
| 13 | Existence of Global Weak Solutions for a 2D Viscous Shallow Water Equations and Convergence to the Quasi-Geostrophic Model显示文摘 | Didier Bresch Beno?t Desjardins | 2003 | Communications in Mathematical Physics (-)2003，，1： | 1 |
| 14 | Assessment of hematologic progenitor engraftment by complete reticulocyte maturation parameters after autologous and allogeneic hematopoietic stem cell transplantation显示文摘 | Antonio T Joaquin S Didier L | 2001 | Haematologica2001，86，1： | 1 |
| 15 | Existence of Global Weak Solutions for a 2D Viscous Shallow Water Equations and Convergence to the Quasi-Geostrophic Model显示文摘 | Didier Bresch Beno?t Desjardins | 2003 | Communications in Mathematical Physics (-)2003，，1： | 1 |
| 16 | Ozone and water deficient reduced growth of aleppopine seedlings显示文摘 | Didier L T Sirkku M | 2003 | Plant Physiology and Biochemistry2003，41，： | 1 |
| 17 | Microsporidian infection is prevalent in healthy people in Cameroon显示文摘 | NKININ S W ASONGANYI T DIDIER E S | 2007 | J Clin Microbiol2007，45，9： | 1 |
| 18 | Measuring Consumer’s Willingness to Payfor Organic and Fair Trade Products 显示文摘 | DIDIER T LUCIE S | 2008 | International Journal ofConsumer Studies2008，32，5： | 1 |
| 19 | Effects of non-ionic iodinated contrast media on patient heart rate and pressures during intra-cardiac or intra-arterial injection显示文摘 | Schmid I Didier D Pfammatter T | 2007 | Int J Cardiol2007，，3： | 1 |
| 20 | Methyl mercaptan and carbonyl sulfide traces removal through adsorption and catalysis on zeolites and layered double hydroxides 显示文摘 | ANDREY R VASILE H DIDIER T CATHERINE L DIDIER A BERNARD C PHILIPPE T | 2011 | Appl Catal A: Gen2011，397，12： | 1 |
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