|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of ghrelin in the regulation of gastric acid secretion involving nitrergic mechanisms in rats显示文摘 | Bilgin H M Tumer C Diken H Kelle M Sermet A | 2008 | Physiol Res2008，57，： | 1 |
| 2 | Opposing effects of ERK and JN K-P38 MAP kinase on apoptosis 显示文摘 | Dikens M Raingeaud J | 1995 | Science1995，270，24： | 1 |
| 3 | Tumor vaccination using mes-senger RNA:prospects of a future therapy 显示文摘 | Kreiter S Diken M Selmi A | 2011 | Curr Opin Immunol2011，23，3： | 1 |
| 4 | Spectral Signatures of Hydrated Proton Vibrations in Water Clusters显示文摘 | Jeffrey M Headrick Eric G Diken Richard S Waiters | 2005 | Science2005，308，： | 1 |
| 5 | Antioxidant activity and total phenolic,organic acid and sugar content in commercial pomegranate juices显示文摘 | Tezcan F Gultekin-ozguven M Diken T | 2009 | Food Chemistry2009，115，： | 1 |
| 6 | In vivo molecular imaging with cetuximab, an anti-EGFR antibody, forprediction of response in xenograft models of human colorectal cancer显示文摘 | GOETZ M HOETKER MS DIKEN M | 2013 | Endoscopy2013，45，6： | 1 |
| 7 | Antioxi- dant activity and total phenolic, organic acid and sugar content in commercial pomegranate juices 显示文摘 | Tezcan F Giiltekin-Ozgtiven M Diken T | 2009 | Food Chem- istry2009，115，3： | 1 |
| 8 | roTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA 显示文摘 | Diken M Kreiter S Vascotto F | 2013 | Cancer Imnmnol Res2013，1，6： | 1 |
| 9 | Isolation and characterization of a gene from Streptomyces sp, strain C5 that coders the ability to convert daunomyein to doxorubiein on Streptomyces lividans TK24 显示文摘 | Dikens M L Strohl W R | 1996 | J Bacteriol1996，178，11： | 1 |
| 10 | Molecular Endoraicroscopy Predicts Tumor Response to Cetuximab Therapy in Human Colon Cancer Xenografts 显示文摘 | Hoetker MS Kiesslich R Diken M | 2012 | Gastroenterology2012，142，： | 1 |
| 11 | mTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA 显示文摘 | Diken M Kreiter S Vascotto F | 2013 | Cancer Immunol Res2013，1，6： | 1 |
| 12 | Tumor vaccination using messenger RNA : prospects of a future therapy 显示文摘 | Kreiter S Diken M Se|mi A | 2011 | Curr Opin Immunol2011，23，3： | 1 |
| 13 | Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis显示文摘 | Xia ZG Dikens M Raingeaud J | 1995 | Science1995，270，2： | 1 |
| 14 | Antioxi- dant activity and total phenolic, organic acid and sugar content in com- mercial pomegranate juices显示文摘 | TEZCAN F GULTEKIN-OZGUVEN M DIKEN T | 2009 | Food Chemistry2009，115，： | 1 |
| 15 | Role of ghrelin in the regulation of gastric acid secretion invol- ving nitrergic mechanisms in rats 显示文摘 | BILGIN H M TUMER C DIKEN H | 2008 | Physiological Research2008，57，4： | 1 |
| 16 | Antioxidant activity and total phenolic, organic acid and sugar content in commercial pomegranate juices显示文摘 | TEZCAN F GULTEKIN-OZGUVEN M DIKEN T | 2009 | Food Chem2009，115，3： | 1 |
| 17 | Tumor vaccination using messenger RNA: prospects of a future therapy显示文摘 | Kreiter S Diken M Selmi A | 2011 | Current Opin Immunol2011，23，3： | 1 |
| 18 | Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation显示文摘 | Diken M Kreiter S Selmi A | 2011 | Gene Ther2011，18，7： | 1 |
| 19 | Role of ghrelin in t he regulation of gastric acid secretion involving nit rergic mechanisms in rat s显示文摘 | Bilgin H M Tumer C Diken H | 2008 | PhysioI Res2008，57，： | 1 |
| 20 | Role of serological rapid antibody test in the management of possible COVID-19 cases显示文摘Although the detection of viral particles by reverse transcription polymerase chain reaction(RT-PCR)is the gold standard diagnostic test for coronavirus disease 2019(COVID-19),the false-negative results constitute a big challenge.AIM To examine a group of patients diagnosed and treated as possible COVID-19 pneumonia whose multiple nasopharyngeal swab samples were negative for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)by RT-PCR but then serological immunoglobulin M/immunoglobulin G(IgM/IgG)antibody against SARS-CoV-2 were detected by rapid antibody test.METHODS Eighty possible COVID-19 patients who had at least two negative consecutive COVID-19 RT-PCR test and were subjected to serological rapid antibody test were evaluated in this study.RESULTS The specific serological total IgM/IgG antibody against SARS-CoV-2 was detected in twenty-two patients.The mean age of this patient group was 63.2±13.1-yearsold with a male/female ratio of 11/11.Cough was the most common symptom(90.9%).The most common presenting chest computed tomography findings were bilateral ground glass opacities(77.2%)and alveolar consolidations(50.1%).The mean duration of time from appearance of first symptoms to hospital admission,to hospital admission,to treatment duration and to serological positivity were 8.6 d,11.2 d,7.9 d,and 24 d,respectively.Compared with reference laboratory values,serologically positive patients have shown increased levels of acute phase reactants,such as C-reactive protein,ferritin,and procalcitonin and higher inflammatory markers,such as erythrocyte sedimentation rate,lactate dehydrogenase enzyme,and fibrin end-products,such as D-dimer.A left shift on white blood cell differential was observed with increased neutrophil counts and decreased lymphocytes.CONCLUSION Our study demonstrated the feasibility of a COVID-19 diagnosis based on rapid antibody test in the cases of patients whose RT-PCR samples were negative.Detection of antibodies against SARS-CoV-2 with rapid antibody test should be included in the diagnostic algorithm in patients with possible COVID-19 pneumonia. | Fatma Yıldırım Pinar Yildiz Gulhan Ozlem Ercen Diken Aylin Capraz Meltem Simsek Berna Botan Yildirim Muhammet Ridvan Taysi Sakine Yilmaz Ozturk Nurcan Demirtas Julide Ergil Adem Dirican Tugce Uzar Irem Karaman Sevket Ozkaya | 2021 | World Journal of Experimental Medicine2021，11，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员