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| 1 | A single subcutaneous dose of tramadol for mild to moderate musculoskeletal trauma in the emergency department显示文摘BACKGROUND: Mild to moderate musculoskeletal trauma is a common cause for an emergency room visit, and frequent pain is one of the cardinal symptoms of consultation. The objective of this study is to assess the perception of a single subcutaneous dose of 50 mg tramadol for pain management in patients with mild to moderate musculoskeletal trauma, likewise to appraise the perception of pain by subcutaneous injection.METHODS: A total of 77 patients, who met inclusion criteria, received a single subcutaneous dose of tramadol. Pain control was evaluated based on the verbal numerical pain scale(0–10) at baseline, 20 and 60 minutes; similarly, pain perception was evaluated secondary to subcutaneous injection of the analgesic.RESULTS: On admission, the average pain perceived by patients was 8; twenty minutes later, 89% of the patients reported fi ve or less, and after sixty minutes, 94% had three or less on the verbal numerical pain scale. Of the patients, 88% reported pain perception by verbal numeric scale of 3 or less by injection of the drug, and 6.5% required a second analgesic for pain control. Two events with drug administration(soft tissue infection and mild abdominal rectus injection) were reported.CONCLUSION: We conclude that a single subcutaneous dose of tramadol is a safe and effective option for the management of patients with mild to moderate pain and musculoskeletal disease in the emergency department. | Alejandro Cardozo Carlos Silva Luis Dominguez Beatriz Botero Paulo Zambrano Jose Bare?o | 2014 | World Journal of Emergency Medicine2014，5，4： | 2 |
| 2 | Resolution of ternary mixtures of rifampicin, isoniazid and pyrazinamide by differential pulse polarography and partial least squares method显示文摘 | Alonso-Lomillo M A Dominguez Renedo O Arcos-Martinez M J | 2001 | Anal Chim Acta2001，449，12： | 1 |
| 3 | PredicHve fac- tors for mortality in patients with methicillin reststant Staphylococcus aureus bloodstream infection: impact on outcome of host, microorganism and therapy显示文摘 | Gasch O Camoez M Dominguez MA d al | 2013 | Clin Mi crobiol Infect2013，19，11： | 1 |
| 4 | Contrasting genetic effectsof major histocompatibility complex on ischemic peripheral nerveand spinal cord injury in female rats 显示文摘 | Dominguez CA Lidman O Olsson T | 2008 | Neurosci Lett2008，443，2： | 1 |
| 5 | Surface analysis of in- hibitor films formed by imidazolines and amides on mild steel in an acidic environment显示文摘 | OLIVARESXOMETL O L1KHAN()VA N V Dominguez Aguilar M A | 2006 | Applied Sur- face Science2006，252，6： | 1 |
| 6 | DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis显示文摘 | GARCIA-DIAZ M DOMINGUEZ O LOPE Z-FERNANDEZ L A | 2000 | J Mol Biol2000，301，4： | 1 |
| 7 | Characteristics of blueing as an alternative chemical conversion treatment on carbon steel显示文摘 | BUSTAMENTE E O DOMINGUEZ M A | 2007 | Surface & Coatings Technology2007，201，： | 1 |
| 8 | Preliminarystudies of biochemical changes(ethoxycoumarin O-deethylaseactivities and vitellogenin induction)in two species shrimp(Farfantepenaeus duorarum and Litopenaeus setiferu)fromthe Gulf of Mexico显示文摘 | Zapata-Perez O Del-Rio M Dominguez J | 2005 | Ecotoxicol Environ Safty2005，61，1： | 1 |
| 9 | Growth and molecular profile of lung cancer cells expressing ectopic LKB1 down-regulation of the phosphatidylinositol 3'-phosphate kinase/PTEN pathway显示文摘 | Jimenez AI Fernandez P Dominguez O | 2003 | Cancer Res2003，63，6： | 1 |
| 10 | Phylogenentic relationships and biogeography of Pseudoxiphophorus (Teleostel: Poeciliidae) based on mitochondrial and nuclear genes显示文摘 | Agorreta A Dominguez - Dominguez O Reina RG | 2013 | Mol Phylogenet Evol2013，66，1： | 1 |
| 11 | Molecular typing of HLA- B27 alleles显示文摘 | Dominguez O Coto E Maninez-Naves E | 1992 | Immunogeneties1992，36，5： | 1 |
| 12 | Resolution of ternary mixtures of rifampicin, isoniazid and pyrazinamide by differential pulse polarography and partial least squares method显示文摘 | LOMILLO M A A DOMINGUEZ R O ARCOS M M J | 2001 | Analytica Chimica Acta2001，449，12： | 1 |
| 13 | Therapeutic options in osteoporosis显示文摘 | Dominguez LJ Scalisi R Barbagal o M | | 0，，1： | 1 |
| 14 | Comparison of the determination of superoxide dismutase and antioxidant capacity in neurological patients using two different procedures 显示文摘 | Serra J A Marschoff E R Dominguez R O | 2000 | Clin Chim Acta2000，301，12： | 1 |
| 15 | Characterization using thermomechanical and differential thermal analysis of the sinterization of Portland clinker doped with CaF2 显示文摘 | Dominguez O Torres-Castillo A Flores-Velez L M | 2010 | Materials Characterization2010，66，4： | 1 |
| 16 | Catalytic hydrotreating of heavy vacuum gas oil on Al- and Ti-pillared clays prepared by conventional and microwave Irradiation methods显示文摘 | Martinez O M J Fetter G Dominguez J M Melo B J A Ramos G R | 2003 | Microporous and Mesoporous Materials2003，58，： | 1 |
| 17 | Growth and molecular profile of lung cancer cells expressing ectopic LKB1:down-regulation of the phosphatidylinositol 3'-phosphate kinase/PTEN pathway显示文摘 | Jimenez A I Fernandez P Dominguez O | 2003 | Cancer Res2003，63，： | 1 |
| 18 | Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis显示文摘 | Morales-Ibanez O Dominguez M Ki S H | | 0，，： | 1 |
| 19 | Growth and molecular profile of lung cancer cells expressing ectopic LKB1 down-regulation of the phosphatidylinositol 3-phosphatekinase/ PTEN pathway显示文摘 | Jimenez AI Fernandez P Dominguez O | 2003 | Cancer Res2003，63，6： | 1 |
| 20 | Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens显示文摘 | Sospedra M Ferrer-Francesch X Dominguez O | 1998 | J Immunol1998，161，11： | 1 |
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