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3篇 您的检索式:作者名="DONGSEOK KIM"
    题名 作者 年代 出处 被引量
1Enumerations of finite topologies associated with a finite graph显示文摘DONGSEOK KIM YOUNG SOO KWON JAEUN LEE 2014KYUNGPOOK Math J2014,54,:1
2Quantitative autonomic function test in differentiation of multiple system atrophy from idiopathic Parkinson disease显示文摘Background:Differential diagnosis of idiopathic Parkinson disease (IPD) and multiple system atrophy-Parkinson type (MSA-P) is challenging since they share clinical features with parkinsonism and autonomic dysfunction.To distinguish MSA-P from IPD when the symptoms are relatively mild,we investigated the usefulness of the quantitative fractionalized autonomic indexes and evaluated the correlations of autonomic test indexes and functional status.Methods:Thirty-six patients with parkinsonism (22 with IPD and 14 with MSA-P) in Soonchunhyang University Bucheon Hospital from February 2014 to June 2015 were prospectively enrolled in the study.We compared fractionalized autonomic indexes and composite autonomic scoring scale between patients with IPD and MSA-P with Hoehn and Yahr (H&Y) score ≤3.Parasympathetic indexes included expiratory/inspiratory ratio during deep breathing,Valsalva ratio (VR),and regression slope of systolic blood pressure (BP) in early phase Ⅱ (vagal baroreflex sensitivity) during Valsalva maneuver.Sympathetic adrenergic indexes were pressure recovery time (PRT) and adrenergic baroreflex sensitivity (BRSa) (BP decrement associated with phase 3 divided by the PRT),sympathetic index 1,sympathetic index 3,early phase Ⅱ mean BP drop,and pulse pressure reduction rate.Additionally,we compared the unified multiple system atrophy rating scale (UMSARS) and H&Y scores and the autonomic indexes in all patients.Results:PRT was significantly different between the IPD and MSA-P groups (P =0.004) despite the similar BP drop during tilt.Cutoff value of PRT was 5.5 s (sensitivity,71.4%;specificity,72.7%).VR (r =-0.455,P =0.009) and BRSa (r =-0.356,P =0.036) demonstrated a significant correlation with UMSARS and H&Y scores.Conclusions:Among the cardiovascular autonomic indexes,PRT can be a useful parameter in differentiating the early stage of MSA-P from that of IPD.Moreover,VR,and BRSa may be the optimal indexes in determining functional symptom severity.Ji-Yun Park Dongseok Yang Hei-Jun Yang Hyun Ah Kim Saeromi Kim Deokhyun Heo Jeong-Ho Park Eek-Sung Lee Tae-Kyeong Lee 2019Chinese Medical Journal2019,,16:1
3FET-based nanobiosensors for the detection of smell and taste显示文摘Various nanobiosensors composed of biomaterials and nanomaterials have been developed,due to their demonstrated advantage of showing high performance.Among various biomaterials for biological recognition elements of the nanobiosensor,sensory receptors,such as olfactory and taste receptors,are promising biomaterials for developing nanobiosensors,because of their high selectivity to target molecules.Field-effect transistors(FET)with nanomaterials such as carbon nanotube(CNT),graphene,and conducting polymer nanotube(CPNT),can be combined with the biomaterials to enhance the sensitivity of nanobiosensors.Recently,many efforts have been made to develop nanobiosensors using biomaterials,such as olfactory receptors and taste receptors for detecting various smells and tastes.This review focuses on the biomaterials and nanomaterials used in nanobiosensor systems and studies of various types of nanobiosensor platforms that utilize olfactory receptors and taste receptors which could be applied to a wide range of industrial fields,including the food and beverage industry,environmental monitoring,the biomedical field,and anti-terrorism.Dongseok Moon Yeon Kyung Cha So-ong Kim Seongyeon Cho Hwi Jin Ko Tai Hyun Park 2020Science China(Life Sciences)2020,63,8:1
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