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2篇 您的检索式：作者名="Dai Huiting"

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		题名	作者	年代	出处	被引量
	1	Rapid evaluation of heterologous chimeric RBD-dimer mRNA vaccine for currently-epidemic Omicron sub-variants as booster shot after inactivated vaccine显示文摘With continuous mutations of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the severe immune escape of Omicron sub-variants urges the development of next-generation broad-spectrum vaccines,especially as booster jabs after high-level vaccination coverage of inactivated vaccines in China and many other countries.Previously,we developed a coronavirus disease 2019(COVID-19)protein subunit vaccine ZF2001?based on the tandem homo-prototype receptor-binding domain(RBD)-dimer of the SARS-CoV-2 spike protein.We upgraded the antigen into a hetero-chimeric prototype(PT)-Beta or Delta-BA.1 RBD-dimer to broaden the cross-protection efficacy and prove its efficiency with protein subunit and mRNA vaccine platforms.Herein,we further explored the hetero-chimeric RBD-dimer mRNA vaccines and evaluated their broad-spectrum activities as booster jabs following two doses of inactivated vaccine(Ⅳ)in mice.Our data demonstrated that the chi-meric vaccines significantly boosted neutralizing antibody levels and specific T-cell responses against the vari-ants,and PT-Beta was superior to Delta-BA.1 RBD as a booster in mice,shedding light on the antigen design for the next-generation COVID-19 vaccines.	Qian Chen Pei Du Yuxuan Han Xuehui Ma Rong Zhang Xiaoyu Rong Xu Zhao Renyi Ma Huiting Yang Anqi Zheng Qingrui Huang Jinghua Yan Hui Wang Xin Zhao Lianpan Dai George F.Gao Qihui Wang	2023	Biosafety and Health2023，5，2：	1
	2	Observation on the Therapeutical Effect of Adjuvant Arthritis in Rats with Medicinal Indirect Moxibustion显示文摘ObservationontheTherapeuticalEffectofAdjuvantArthritisinRatswithMedicinalIndirectMoxibustion￥ZhuBaijun;WangYuanchao;DaiHuitin...	Zhu Baijun Wang Yuanchao Dai Huiting Xu Qingyan(Institute of Acupuncture and Moxibustion China Academy of TCM, 100700)	1995	中国针灸1995，15，S2：	0

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