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2篇 您的检索式:作者名="Daiki Omata"
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1Development of cell-targeting bubble liposome for effective gene delivery with ultrasound显示文摘Previously,we developed a gene delivery system using Bubble liposomes(perfluoropropane gas-entrapping liposomes;BLs)and ultrasound(US)[1].The combination of BLs and US can deliver plasmid DNA into the cytoplasm via the formation of transient membrane pores by cavitation.To enhance the efficiency of gene delivery,it is important to induce the cavitation of BLs at the vicinity of cells.In brief,cell-binding BLs would be useful for gene delivery to induce the cavitation on the cell membrane.Mutsumi Sugii Ryo Suzuki Yusuke Oda Johan Unga Daiki Omata Hitoshi Uruga Yoichi Negishi Kazuo Maruyama 2016Asian Journal of Pharmaceutical Sciences2016,11,1:0
2Development of tissue-selective gene delivery system with ultrasound显示文摘Gene therapy is applied into cardiovascular diseases,cancer and diseases that are due to genomic causes.Viral vectors are efficient carriers of genes for transduction,but some problems have become evident.Delivery vectors that are highly potent in terms of gene transduction efficiency should also be safe and easy to apply.Non-viral vectors have recently received focus as gene carriers,but their transduction efficiency is very low and not suitable for in vivo gene delivery.In addition,it is important to develop tissue-specific or selective gene delivery system to avoid side effects in gene therapy.Ryo Suzuki Daiki Omata Yusuke Oda Mutsumi Sugii Hitoshi Uruga Johan Unga Yoichi Negishi Sanae Oda Kazuo Maruyama 2016Asian Journal of Pharmaceutical Sciences2016,11,1:0
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