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| 1 | A mouse model for HBV immunotolerance and immunotherapy显示文摘一个适当小动物模型的缺乏仍然是一个主要障碍因为学习 immunotolerance 和 immunopathogenesis 由肝炎 B 病毒(HBV ) 导致了感染。在这研究,我们与 recombinant 在感染以后与持续 HBV viremia 报导一个老鼠模型带一个可复制的 HBV 染色体(AAV/HBV ) 的联系 adeno 的病毒(AAV ) 。类似于临床的 HBV 搬运人,感染 AAV/HBV 的老鼠为对 HBV 表面抗原(HBsAg ) 的抗体是 sero 否定的。有面对铝助手疫苗的常规 HBV 的免疫没能在这些老鼠对 HBV 得到有免疫力的回答。为了识别一支疫苗,那能潜在地围绕这忍耐, TLR9 收缩筋 CpG 作为一个助手被加到 HBsAg。有 HBsAg/CpG 的老鼠的种痘导致了 viremia,而且强壮的抗体生产和 T 房间回答的不仅清理。而且, DNA 复制和 HBV 的蛋白质表示显著地在 AAV/HBV-infected 鼠标的肝被减少。因此, AAV/HBV-infected 老鼠可以作为一个柔韧的模型被使用调查 HBV immunotolerance 并且为开发新奇免疫疗法根除的内在的机制 HBV 感染。 | Dan Yang Longchao Liu Danming Zhu Hua Peng Lishan Su Yang-Xin Fu Liguo Zhang | 2014 | Cellular & Molecular Immunology2014,11,1: | 25 |
| 2 | Failure mode investigation of fuel cell for vehicle application显示文摘 | Zhongjun HOU Renfang WANG Keyong WANG Weiyu SHI Danming XING Hongchun JIANG | 2017 | Frontiers in Energy2017,11,3: | 2 |
| 3 | Interface Reversible Electric Field Regulated by Amphoteric Charged Protein-Based Coating Toward High-Rate and Robust Zn Anode显示文摘Metallic interface engineering is a promising strategy to stabilize Zn anode via promoting Zn^(2+) uniform deposition.However,strong interactions between the coating and Zn^(2+) and sluggish transport of Zn^(2+) lead to high anodic polarization.Here,we present a bio-inspired silk fibroin(SF)coating with amphoteric charges to construct an interface reversible electric field,which manipulates the transfer kinetics of Zn^(2+) and reduces anodic polarization.The alternating positively and negatively charged surface as a build-in driving force can expedite and homogenize Zn^(2+) flux via the inter-play between the charged coating and adsorbed ions,endowing the Zn-SF anode with low polarization voltage and stable plating/stripping.Experimental analyses with theo-retical calculations suggest that SF can facilitate the desolvation of[Zn(H_(2)O)_(6)]^(2+) and provide nucleation sites for uniform deposition.Consequently,the Zn-SF anode delivers a high-rate performance with low voltage polarization(83 mV at 20 mA cm^(−2)) and excellent stability(1500 h at 1 mA cm^(−2);500 h at 10 mA cm^(−2)),realizing exceptional cumulative capacity of 2.5 Ah cm^(−2).The full cell coupled with Zn_(x)V_(2)O_(5)·nH_(2)O(ZnVO)cathode achieves specific energy of~270.5/150.6 Wh kg^(−1)(at 0.5/10 A g^(−1))with-99.8% Coulombic efficiency and retains~80.3%(at 5.0 A g^(−1))after 3000 cycles. | Meihua Zhu Qing Ran Houhou Huang Yunfei Xie Mengxiao Zhong Geyu Lu Fu-Quan Bai Xing-You Lang Xiaoteng Jia Danming Chao | 2022 | Nano-Micro Letters2022,14,12: | 2 |
| 4 | Intestinal nonHodgkin's lymphoma:a multieenter prospective clinical study from the German Study Group on Intestinal non-Hodgkin's Lymphoma显示文摘 | Ullrich R Heise W | 2003 | J Clin Oncol2003,21,14: | 1 |
| 5 | Protective effect of HMG-CoA reductase in hibitor on experimental renal ischemiareper fusion injury显示文摘 | Yokota N O Donnell M DanMs F | 2003 | Am J Nephrol2003,,23: | 1 |
| 6 | Associations evoked during memory enepding rescruit the context- network显示文摘 | Peters J Danm I Gizewski E | 2009 | Hippocampus2009,19,2: | 1 |
| 7 | High - level resistance to gentamicin in clinical isolates of Streptococcus ( Enteroeoeeus ) faecium 显示文摘 | Eliopoulos GM Wennersten C Zighelboim - Danm S | 1988 | Antimicrob Agents Chemother1988,32,10: | 1 |
| 8 | Protective effect of HMG - CoA reductase irrhibitor on expenimental renal ischemia -reperfusion injury显示文摘 | YOKOTA N O DONNELL M DANM S F | 2003 | Am J Nephrol2003,2,: | 1 |
| 9 | A novel non-dripping oligomeric flame retardant for polyethylene terephthalate显示文摘 | Ban Danming Wang Yuzhong Yang Bing | 2004 | European Polymer Journal2004,40,8: | 1 |
| 10 | Diagnostic morphological features of PDGFRA-mutated gastrointestinal stromal tumors:molecular genetic and histologic analysis of 60 cases of gastric gastrointestinal stromal tumors显示文摘 | Danm O Grossmann P Vanecek T | 2007 | Ann Diagn Pathol2007,11,1: | 1 |
| 11 | Delayed nausea and vomiting continue to reduce patients' quality of life after highly and moderately emetogenie chemotherapy de- spite antiemetic treatment 显示文摘 | Bloechl - Danm B Deuson RR Mavros P | 2006 | J Clinncol2006,24,27: | 1 |
| 12 | Associations evoked during memory enepding rescruit the context-network 显示文摘 | Peters J Danm I Gizewski E | 2009 | Hippocampus2009,19,2: | 1 |
| 13 | Clinical predictor of dysphagla and aspiration risk:outcome measures in acute stroke patients显示文摘 | DanM SK Ballo A Mahoney MC | 2000 | Arch Phy Med Rehabil2000,81,5: | 1 |
| 14 | Ozone production in the New York City urban plume显示文摘 | Kleinman L I Danm P H Imre D G | 2000 | J Geophys Res2000,105,14: | 1 |
| 15 | Utilization of exogenous glycerophos- phodiesters and glycerol-3-phosphate by inositol-starved yeast, Saccharomyces u'oarum 显示文摘 | Paltauf F Zinser E Danm G | 1985 | Biochirnica et Biophysica Acta1985,835,2: | 1 |
| 16 | Ultrasonic synthesis of polyaniline nanotubes containing Fe 3 O 4 nanoparticles显示文摘 | Xiaofeng Lu Hui Mao Danming Chao Wanjin Zhang Yen Wei | 2006 | Journal of Solid State Chemistry2006,,8: | 1 |
| 17 | Piezoelectric Nanogenerator Based on Electrospun Cellulose Acetate/Nanocellulose Crystal Composite Membranes for Energy Harvesting Application显示文摘Nanogenerators,as the typical conversion of mechanical energy to electrical energy devices,have great potential in the application of providing sustainable energy sources for powering miniature devices.In this work,cellulose acetate/cellulose nanocrystal(CA/CNC)composite nanofiber membranes were prepared by electrospinning method and then utilized to manufacture a flexible pressure-driven nanogenerator.The addition of CNC not only increased the content of piezoelectric cellulose I crystallization but also strengthened the mechanical deformation of the nanofiber membranes,which could greatly enhance the piezoelectric performance of CA/CNC composite membranes.The CA/CNC composite nanofiber membrane with 20%(mass fraction)of CNC(CA/CNC-20%)showed optimal piezoelectric conversion performance with the output voltage of 1.2 V under the force of 5 N(frequency of 2 Hz).Furthermore,the output voltage of the CA/CNC-20%nanogenerator device exhibited a linear relationship with applied impact force,indicating the great potential in pressure sensors. | SUN Bolun CHAO Danming WANG Ce | 2022 | Chemical Research in Chinese Universities2022,38,4: | 1 |
| 18 | MR measure- ment of normal and pathologic brainstem diameters显示文摘 | Koehler P R Haughton V M DanMs D L | 1985 | AJNR Am J Neuroradiol1985,6,3: | 1 |
| 19 | Construction of eukaryotic expression vector encoding ATP synthase lipid-binding protein-like protein gene of Sj and its expression in HeLa cells显示文摘克隆并且构造包含 ATP synthase 类脂化合物绑定的 recombinant plasmid 的目的血吸虫 japonicum 的像蛋白质的蛋白质基因,(SjAslp ) 并且把它变成哺乳动物的房间表示客观蛋白质。由聚合酶链反应(PCR ) 的方法技术, SjAslp 从构造 recombinant plasmid pBCSK+/SjAslp 被放大,并且插入了到克隆向量 pUCm-T。然后, SjAslp 是进真核细胞的表示向量 pcDNA3.1 (+) 的 subcloned。在由定序的 PCR,限制的酶消化和 DNA 识别它以后, recombinant plasmid 是进用 recombinant 蛋白质的 electroporation,和表示的 HeLa 房间的 transfected 被 immunocytochemical 分析试金。结果 558 bp 的特定的基因碎片成功地被放大。SjAslp 的 DNA 疫苗成功地被构造。Immunocytochemical 试金证明 SjAslp 在 HeLa 房间的细胞质被表示。结论 SjAslp 基因能在真核细胞的系统被表示,它对 schitosomiasis 为 SjAslp DNA 疫苗的开发打基础。 | Ouyang Danming Hu Yongxuan Li Mulan Zeng Xiaojun He Zhixiong Yuan Caijia | 2008 | Journal of Medical Colleges of PLA(China)2008,23,2: | 1 |
| 20 | The perioperative implica-tions of obstructive sleep apnea显示文摘 | Danm Theresa T Michael J Kremor | | 0,,05: | 1 |