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| 1 | Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume显示文摘Objective:To investigate the hypolipidaemic and antioxidant effects of aqueous leaf extract of Enicoslemma littorale(E.littorale)Blume(Ens)against ethanol induced hepatic injury in albino rats.Methods:Male albino rats of six numbers in each group were undertaken for study.Hypolipidaemic and antioxidant effect of E.littorale Blume(Ens)aqueous leaf extract at a dosage of 250 mg/kg bw was evaluated.Results:Levels of serum and tissue cholesterol,triglycerides and free fatty acids were elevated and levels of tissue thiobarbituric acid reactive substances(TBARS)and lipid hydroperoxide were increased in ethanol treated rats.The activity levels of liver antioxidant enzymes such as superoxide dismutase(SOD),catalase(CAT),glutathione peroxidase(GPX)and glutathione-s-transferase(GST)were decreased.After adiminstration of extract of E,littorale Blume,levels of cholesterol,triglycerides and free fatty acids were decreased in serum and liver tissue,levels of TBARS and lipid hydroperoxide were decreased,and Ever antioxidant enzymes were increased in liver tissue;Conclusions:It can be concluded that the aqueous leaf extract of E,littorale Blume(Ens)has potent restorative effect on hyperlipidaemic and oxidative stress. | Thirumalai T Viviyan Therasa S Elumalai EK David E | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，5： | 12 |
| 2 | Hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rat显示文摘Objective:To evaluate the hypoglycemic effect of Brassica juncea(seeds) on streptozotocin induced diabetic male albino rats.Methods:Hypoglycemic activity of Brassica juncea(seeds)aqueous extract at a dose of 250,350 and 450 mg/kg body weight was evaluated.Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated.Results:The serum insulin levels were recorded a significant depletion in all groups,short term as well as long term diabetic animals,when compared to that of normal animals.A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term groups.Conclusions:The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat. | T Thirumalai S Viviyan Therasa EK Elumalai E David | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 9 |
| 3 | Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity显示文摘Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome.Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous chromosomes.Wild species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding efforts.As a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid potato.Nearly a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic load.The StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent manner.Knowledge of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids. | Genevieve Hoopes Xiaoxi Meng John P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.Kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers | 2022 | Molecular Plant2022，15，3： | 4 |
| 4 | HMG:心脏病发作的记忆储存在我们的基因中显示文摘遗传因素和环境因素影响我们的心血管疾病风险。如今。在一项新的研究中,来自瑞典乌普萨拉大学的研究人员发现心脏病发作的记忆能够通过表观遗传变化储存在我们的基因中。相关研究结果在线发表在Human Molecular Genetics期刊上。 | Mathias Rask-Andersen David Martinsson Muhammad Ahsan Stefan Enroth Weronica E. Ek Ulf Gyllensten sa Johansson | 2016 | 现代生物医学进展2016，16，31： | 3 |
| 5 | Intense and exhaustive exercise induce oxidative stress in skeletal muscle显示文摘 | T Thirumalai S Viviyan Therasa EK Elumalai E David | 2011 | Asian Pacific Journal of Tropical Disease2011，，1： | 2 |
| 6 | Laparoendoscopic single-site minor hepatectomy for liver tumors显示文摘 | Ek Tan Victor Lee Stephen Chang Iyer Ganpathi Krishnakumar Madhavan Davide Lomanto | 2012 | Surgical Endoscopy2012，，7： | 2 |
| 7 | Simultaneous multiple time scale imaging for kHz-MHz high-speed accelerometry显示文摘Fast transient events,such as the disintegration of liquid bodies or chemical reactions between radical species,involve various processes that may occur at different time scales.Currently,there are two alternatives for monitoring such events:burst-or high-speed imaging.Burst imaging at ultrahigh speeds(~100 MHz to THz)allows for the capture of nature's fastest processes but only for a narrowly confined period of time and at a repetition rate of~10 Hz.Monitoring long lasting,rapidly evolving transient events requires a significantly higher repetition rate,which is met by existing~kHz to 1 MHz high-speed imaging technology.However,the use of such systems eliminates the possibility to observe dynamics occurring on the sub-microsecond time scale.In this paper,we present a solution to this technological gap by combining multiplexed imaging with high-speed sensor technology,resulting in temporally resolved,high-spatial-resolution image series at two simultaneous time scales.We further demonstrate how the collection of such data opens up the tracking of rapidly evolving structures up to MHz burst rates over long durations,allowing,for the first time,to our knowledge,the extraction of acceleration fields acting upon the liquid bodies of an atomizing spray in two dimensions at k Hz frame rates. | VASSILY KORNIENKO DAVID ANDERSSON MEHDI STITI JONAS RAVELID SIMON EK ANDREAS EHN EDOUARD BERROCAL ELIAS KRISTENSSON | 2022 | Photonics Research2022，10，7： | 1 |
| 8 | Deactivation of HDS catalysts in deoxygenation of vegetable oils显示文摘 | David Kubi?ka Jan Horá?ek | 2010 | Applied Catalysis A General2010，，1： | 1 |
| 9 | Sep to ptic dysplasis: MR Imaging 显示文摘 | Barkovich JA Fram EK David N | 1989 | Radiology1989，171，： | 1 |
| 10 | Macrophage accumulation and renal fibrosis are independent of maerophage migration inhibitory factor in mouse obstructive nephropathy显示文摘 | Rice EK Nikolic-Paterson DJ David JR | 2004 | Nephrology (Car!ton)2004，9，5： | 1 |
| 11 | Geographical and taxonomic biases in invasion ecology显示文摘 | Petr Py?ek David M. Richardson Jan Pergl Vojtěch Jaro?ík Zuzana Sixtová Ewald Weber | 2008 | Trends in Ecology & Evolution2008，，5： | 1 |
| 12 | Long-term outcomes of percutaneous nephrolithotomy compared to shock wave lithotripsy and conservative management显示文摘 | Amy EK Andrew JL David EP | 2008 | J Urol2008，179，6： | 1 |
| 13 | Long-term outcomes of percutaneous nephrolithotomy compared to shock wave lithotripsy and conservative management 显示文摘 | Amy EK Andrew JL David EP | 2008 | J Urol2008，179，6： | 1 |
| 14 | Free plasma metanephrines as a screening test for pheochromocytoma in low-risk patients显示文摘 | Jan Václavík David Stejskal Bo?ek La?ňák Marie Lazárová Libor Jedelsky Lenka Kadalová Marie Jano?ová Zdeněk Fry?ák Petr Vl?ek | 2007 | Journal of Hypertension2007，，7： | 1 |
| 15 | Hydroprocessed rapeseed oil as a source of hydrocarbon-based biodiesel显示文摘 | Pavel ?imá?ek David Kubi?ka Gustav ?ebor Milan Pospí?il | 2008 | Fuel2008，，3： | 1 |
| 16 | Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke: pooled analysis of placebo data from the stroke-acute ischemic NXY treatment (SAINT) I and SAINT II trials显示文摘 | Brett C Scott EK David T et a1 | 2009 | Stroke2009，40，9： | 1 |
| 17 | Contrast nephropathy显示文摘 | David EK Abdallah GR Andrew W | 2003 | Am J Cardiovasc Drugs2003，3，6： | 1 |
| 18 | Quatification of the relationship between insulin sensitivity and -cell function in human subjects显示文摘 | Steven EK Ronald LP David KM | 1993 | Diabetes1993，2，： | 1 |
| 19 | Dealing with energy demand:the AMP-activated protein kinase 显示文摘 | Bruce EK Ken IM David S et a1 | 1999 | Trends Biochem Sci1999，24，1： | 1 |
| 20 | Restorative effect of Eclipta alba in CCl 4 induced hepatotoxicity in male albino rats显示文摘 | T Thirumalai E David S Viviyan Therasa EK Elumalai | 2011 | Asian Pacific Journal of Tropical Disease2011，，4： | 1 |
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