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| 1 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 2 | Comparison of original and modified BCR sequential extraction procedures for the fractionation of copper, iron, lead, manganese and zinc in soils and sediments显示文摘 | Katherine F Mossop Christine M Davidson | 2002 | Analytica Chimica Acta2002，，1： | 2 |
| 3 | Periodic Solution of a Lotka Voherra Predator-prey Model with Dispersion and Time Delays 显示文摘 | R Xu M A J Chaplain F A Davidson | 2004 | Applied Mathematics and Computation2004，148，： | 1 |
| 4 | Persistence and stability for a two-species ratio-dependent predator-prey system with distributed time delay 显示文摘 | Xu R Davidson F A Chaplain M A J | 2002 | Journal of Mathematical Analysis and Applications2002，269，： | 1 |
| 5 | Performance loss factors for optical communication through clear air turbulence 显示文摘 | Ricklin J C Bucalille S Davidson F M | 2003 | Proceedings of the SPIE2003，5160，： | 1 |
| 6 | Periodic Solutions for a Delayed Predator-prey Model of Prey Dispersal in Twopatch Environments 显示文摘 | XU Rtti CHAPLAIN M A J DAVIDSON F A | 2004 | Nonlinear Analysis2004，，5： | 1 |
| 7 | Comparison of original and modified I3CR sequential extraction procedures for the fractionation of copper, iron, lead, manganese and zinc in soils and sediments 显示文摘 | Mossop K F Davidson C M | 2003 | Analytiea Chimica Acta2003，478，1： | 1 |
| 8 | Skin Tears: Care and Management of the Older Aduh at Home显示文摘 | Holmes R F Davidson M W Thompson B J | 2013 | Home Healthc Nurse2013，31，2： | 1 |
| 9 | Persistence and Global Stability of a Ratio-Dependent Predator-Prey Model with Stage Structure显示文摘 | Chaplain M A J Davidson F A | 2004 | Appl Math Comput2004，158，： | 1 |
| 10 | Extraction of gallium and germanium from domestic resources 显示文摘 | JUDD J C WARDELL M P DAVIDSON C F | 1988 | Light Metals1988，，： | 1 |
| 11 | Assessing available carbon:comparison of techniques across selected forest soils显示文摘 | Davidson E A Galloway L F Strand M K | 1987 | Communications in Soils Science and Plant Analysis1987，18，： | 1 |
| 12 | Permanence and periodicity of a delayed ratio-dependent predator-prey model withstage structure显示文摘 | Xu Rui Chaplain M A J Davidson F A | 2005 | Math Anal Appl2005，303，： | 1 |
| 13 | Global stability of a stage-structured predator-prey model with prey dispersal 显示文摘 | XU R CHAPLAIN M A J DAVIDSON F A | 2005 | Appl Math Comput2005，171，： | 1 |
| 14 | Wavelet packet division multiplexing and wavelet packet design under timing error effects 显示文摘 | Wong K M Wu J F Davidson T N | 1997 | IEEE Trans on Signal Processing1997，45，12： | 1 |
| 15 | Polyurethane Elastomers Based on Polypropylene Glycol Modified Poly (Ethylene Ether Carbonate) Diols显示文摘 | Harris R F Joseph M D Davidson C | | 0，，20： | 1 |
| 16 | Polyurethane elastomers based on molecular weight advanced poly(ethylene e-ther carbonate)diols I Comparison to commercial diols显示文摘 | Harris R F Joseph M D Davidson C | 1990 | Journal of Applied Polymer Science1990，，： | 1 |
| 17 | Airborne concentrations and dry deposition fluxes of particulate species to surrogate surfaces deployed in southern lake Michigan显示文摘 | Zufall M Z Davidson C I Caffrey P F | 1998 | Environmental Science and Technology1998，32，： | 1 |
| 18 | High capacity anode materials for Li-ion batteries based on spinel metal oxides AMn204 显示文摘 | COURTEL F M DUNCAN H ABU-LEBDEH Y DAVIDSON 1 J | 2011 | Journal of Materials Chemistry2011，21，10： | 1 |
| 19 | Human pluripotent stem cell strategies for age-related macular degeneration 显示文摘 | Davidson K C Guymer R H Pera M F | 2014 | Optom Vis Sci2014，91，8： | 1 |
| 20 | Periodic Solutions for A Predator-prey Model with Holling-type Functional Response and Time Delay显示文摘 | Xu Rui Chaplin M A Davidson F A | 2005 | Appl Math Comput2005，161，： | 1 |
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