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| 1 | 连续冷却过程中的相变本构方程显示文摘如何有效地预测在不同工艺条件下材料的微观结构和力学性能,是许多钢铁公司非常关注的重要课题之一。以连续冷却过程中的自由能理论为基础,成功地开发出一套在连续冷却过程中统一的相变本构方程。该本构方程可用来预测钢材在不同的冷却速度下从奥氏体到铁素体、珠光体或贝氏体的开始转变点和结束转变点,同时还可用来预测各相转变的体积分数。利用优化算法通过缩小试验数据和预测数据之间的误差来确定本构方程中的材料常数,得出DINSAE5140钢种相变本构方程的模型参数,并且利用该相变本构方程对DINSAE5140钢种的相变过程进行详细地研究。研究结果表明,利用所开发的模型参数得出的预测连续冷却转变(Continuous cooling transformation,CCT)曲线和相变过程中各相的转变体积分数与试验数据非常一致,该统一的本构方程的建立为预测相变过程提供了一种有效的方法。 | 阳代军 宁林新 林建国 DEAN T A | 2009 | 机械工程学报2009，45，2： | 4 |
| 2 | Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy显示文摘AIM: To study the prognostic value of adjuvant chemo-therapy in patients with pancreatic, ductal adenocar-cinoma.METHODS: Lymph nodes from 106 patients with resectable pancreatic ductal adenocarcinoma were systematically sampled. A total of 318 lymph nodes classified histopathologically as tumor-free were examined using sensitive immunohistochemical assays. Forty-three (41%) of the 106 patients were staged as pT1/2, 63 (59%) as pT3/4, 51 (48%) as pN0, and 55 (52%) as pN1. The study population included 59 (56%) patients exhibiting G1/2, and 47 (44%) patients with G3 tumors. Patients received no adjuvant chemo- or radiation therapy and were followed up for a median of 12 (range: 3.5 to 139) mo.RESULTS: Immunostaining with Ber-EP4 revealed nodal microinvolvement in lymph nodes classified as “tumor free” by conventional histopathology in 73 (69%) out of the 106 patients. Twenty-nine (57%)of 51 patients staged histopathologically as pN0 had nodal microinvolvement. The five-year survival probability for pN0-patients was 54% for those without nodal microinvolvement and 0% for those with nodal microinvolvement. Cox-regression modeling revealed the independent prognostic effect of nodal microinvolvement on recurrence-free (relative risk 2.92, P = 0.005) and overall (relative risk 2.49, P = 0.009) survival.CONCLUSION: The study reveals strong and independent prognostic significance of nodal microinvolvement in patients with pancreatic ductal adenocarcinoma who have received no adjuvant therapy. The addition of immunohistochemical findings to histopathology reports may help to improve risk stratification of patients with pancreatic cancer. | Emre F Yekebas Dean Bogoevski Michael Bubenheim Bjrn-Christian Link Jussuf T Kaifi Robin Wachowiak Oliver Mann Asad Kutup Guellue Cataldegirmen Lars Wolfram Andreas Erbersdobler Christoph Klein Klaus Pantel Jakob R Izbicki | 2006 | World Journal of Gastroenterology2006，12，40： | 3 |
| 3 | The Importance of Medial Support in Locked Plating of Proximal Humerus Fractures显示文摘 | Michael J Gardner Yoram Weil Joseph U Barker Bryan T Kelly David L Helfet Dean G Lorich | 2007 | Journal of Orthopaedic Trauma2007，，3： | 2 |
| 4 | Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data显示文摘 | Alan D Lopez Colin D Mathers Majid Ezzati Dean T Jamison Christopher JL Murray | 2006 | The Lancet . 2006 (9524)2006，，9524： | 2 |
| 5 | WJSC 6^(th) Anniversary Special Issues(2):Mesenchymal stem cells “Ins” and “Outs” of mesenchymal stem cell osteogenesis in regenerative medicine显示文摘Repair and regeneration of bone requires mesenchymal stem cells that by self-renewal,are able to generate a critical mass of cells with the ability to differentiate into osteoblasts that can produce bone protein matrix(osteoid)and enable its mineralization.The number of human mesenchymal stem cells(hMSCs)diminishes with age and ex vivo replication of hMSCs has limited potential.While propagating hMSCs under hypoxic conditions may maintain their ability to self-renew,the strategy of using human telomerase reverse transcriptase(hTERT)to allow for hMSCs to prolong their replicative lifespan is an attractive means of ensuring a critical mass of cells with the potential to differentiate into various mesodermal structural tissues including bone.However,this strategy must be tempered by the oncogenic potential of TERT-transformed cells,or their ability to enhance already established cancers,the unknown differentiating potential of high population doubling hMSCs and the source of hMSCs(e.g.,bone marrow,adipose-derived,muscle-derived,umbilical cord blood,etc.)that may provide peculiarities to self-renewal,differentiation,and physiologic function that may differ from non-transformed native cells.Tissue engineering approaches to use hMSCs to repair bone defects utilize the growth of hMSCs on three-dimensional scaffolds that can either be a base on which hMSCs can attach and grow or as a means of sequestering growth factors to assist in the chemoattraction and differentiation of native hMSCs.The use of whole native extracellular matrix(ECM)produced by hMSCs,rather than individual ECM components,appear to be advantageous in not only being utilized as a three-dimensional attachment base but also in appropriate orientation of cells and their differentiation through the growth factors that native ECM harbor or in simulating growth factor motifs.The origin of native ECM,whether from hMSCs from young or old individuals is a critical factor in'rejuvenating'hMSCs from older individuals grown on ECM from younger individuals. | Dean T Yamaguchi | 2014 | World Journal of Stem Cells2014，6，2： | 2 |
| 6 | A review of the development of creep age forming: Experimentation, modelling and applications显示文摘 | Lihua Zhan Jianguo Lin T A Dean | 2010 | International Journal of Machine Tools and Manufacture2010，，1： | 2 |
| 7 | Effect of Laminar Cooling on Phase Transformation Evolution in Hot Rolling Process显示文摘The effect of temperature variation owing to the cooling pattern(CP)on the microstructural evolution was investigated by establishing a thermomechanical coupled FE(finite element)model.A set of constitutive equations of phase transformation was implanted into the commercial FE solver MARC through the user defined subroutine CRPLAW,and the temperature field was calculated by another user defined subroutine FILM.The results show that the final microstructure is completely bainite phase for CP one,98% of bainite phase and 2% of ferrite phase for CP two,and 55% of bainite phase,35% of pearlite phase and 10% of ferrite phase for CP three. | NING Lin-xin YANG Dai-jun J Lin T A Dean | 2010 | Journal of Iron and Steel Research(International)2010，17，10： | 2 |
| 8 | Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data显示文摘 | Alan D Lopez Colin D Mathers Majid Ezzati Dean T Jamison Christopher JL Murray | 2006 | 2006 (9524)2006，，9524： | 2 |
| 9 | Tumour stem cells and drug resistance显示文摘 | Dean M Fojo T Bates S | 2005 | Nat Rev Cancer2005，5，： | 1 |
| 10 | Modelling of springback in creepforming thick aluminum sheets 显示文摘 | Ho K C Lin J Dean T A | 2004 | International Journal ofPlasticity2004，20，： | 1 |
| 11 | Entrepreneurship as the nexus of individual and opportunity: A structuration view显示文摘 | Sarason Y Dean T Dillard J | 2006 | Journal of Business Venturing2006，21，3： | 1 |
| 12 | Anderson Photoeatalytic oxidation of acetone vapor on TiO2/ZrO2 thin films显示文摘 | Zorn Michael E Tompkins Dean T Zeltner Walter A | 1999 | Applied Cat ''dysis B: Environmental1999，23，1： | 1 |
| 13 | An examination of the impact of initial founding conditions and decisions upon the performance of new bank start-ups显示文摘 | Bamford C E Dean T J McDougall P P | 1990 | Joumal of Business Venturing1990，15，： | 1 |
| 14 | Tumour stem cells and drug resistance显示文摘 | Dean M Fojo T Bates S | 2005 | Nat Rev Can- cer2005，5，4： | 1 |
| 15 | The zona pellucida: Using molecular genetics to study the mammalian egg coat 显示文摘 | RANKIN T DEAN J | 2000 | Reviews of Reproduction2000，，5： | 1 |
| 16 | History of water- column anoxia in the Black Sea indicated by pyrite framboids size distributions显示文摘 | WILKIN R T ARTHUR M A DEAN W E | 1997 | Earth and Planetary Science Letters1997，148，34： | 1 |
| 17 | Toward a theory of sustainable entrepreneurship : reducing enviromental degradation through entrepeneurial action 显示文摘 | DEAN T MCMULLEN J | 2007 | Journal of Business Venturing2007，22，1： | 1 |
| 18 | The interfacialheat transfer coeYcient in hot die forging of titaniumalloy显示文摘 | Hu Z M Brooks J W Dean T A | 1998 | Proceedings of the Institution of MechanicalEngineers Part C: Journal of Mechanical EngineeringScience1998，212，6： | 1 |
| 19 | In Situ generation of palladium nanoparticles:A simple and highly active protocol for oxygen-pro- moted ligand-free Suzuki coupling reaction of aryl chlorides显示文摘 | CHO J K NAJMAN R DEAN T | 2007 | American Ceramic Society Bulletin2007，9，40： | 1 |
| 20 | Tumour stem cells and drug resistance 显示文摘 | Dean M Fojo T Bates S | 2005 | Nat Rev Cancer2005，5，4： | 1 |
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