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| 1 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘 | M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz | 2006 | Cytotherapy2006，，4： | 11 |
| 2 | Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders显示文摘Glutamate is the predominant excitatory neurotransmitter in the human brain and it has been shown that prolonged activation of the glutamatergic system leads to nerve damage and cell death. Following release from the pre-synaptic neuron and synaptic transmission, glutamate is either taken up into the presynaptic neuron or neighbouring glia by transmembrane glutamate transporters. Excitatory amino acid transporter(EAAT) 1 and EAAT2 are Na+-dependant glutamate transporters expressed predominantly in glia cells of the central nervous system. As the most abundant glutamate transporters, their primary role is to modulate levels of glutamatergic excitability and prevent spill over of glutamate beyond the synapse. This role is facilitated through the binding and transportation of glutamate into astrocytes and microglia. The function of EAAT1 and EAAT2 is heavily regulated at the levels of gene expression, post-transcriptional splicing, glycosylation states and cell-surface trafficking of the protein. Both glutamatergic dysfunction and glial dysfunction have been proposed to be involved in psychiatric disorder. This review will present an overview of the roles that EAAT1 and EAAT2 play in modulating glutamatergic activity in the human brain, and mount an argument that these two transporters could be involved in the aetiologies of schizophrenia and affective disorders as well as represent potential drug targets for novel therapies for those disorders. | Georgia M Parkin Madhara Udawela Andrew Gibbons Brian Dean | 2018 | World Journal of Psychiatry2018，8，2： | 9 |
| 3 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement显示文摘 | M Dominici K Le Blanc I Mueller I Slaper-Cortenbach Fc Marini Ds Krause Rj Deans A Keating Dj Prockop Em Horwitz | 2006 | Cytotherapy2006，，4： | 9 |
| 4 | Stem cell therapy as an emerging paradigm for stroke ( STEPS) Ⅱ显示文摘Cell-based therapies represent a new therapeutic approach for stroke.In 2007,investigators from academia,industry leaders,and members of the National Institutes of Health crafted recommendations to facilitate the | Savitz SI Chopp M Deans R Carmichael ST Phinney D Wechsler L | 2011 | 中华神经外科疾病研究杂志2011，10，3： | 5 |
| 5 | ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction显示文摘 | Eugene Braunwald Elliott M Antman John W Beasley Robert M Califf Melvin D Cheitlin Judith S Hochman Robert H Jones Dean Kereiakes Joel Kupersmith Thomas N Levin Carl J Pepine John W Schaeffer Earl E Smith David E Steward Pierre Theroux Raymond J Gibbons J | 2000 | Journal of the American College of Cardiology2000，，3： | 4 |
| 6 | The spectrum of neuromyelitis optica显示文摘 | Dean M Wingerchuk Vanda A Lennon Claudia F Lucchinetti Sean J Pittock Brian G Weinshenker | 2007 | Lancet Neurology2007，，9： | 3 |
| 7 | 中国大陆居民对中风的危险因素、征兆、应急处理及信息获取等相关认知的调查研究(英文)显示文摘目的:以中国大陆居民为受访对象,就中风的认知和预防进行问卷调查,以推进预防中风的健康教育活动。方法:选择大陆两个主要城市(武汉和成都)公园、商场及其他公共场所的居民为对象,进行一项有关中风知识标准化的横截面问卷调查,内容包括风险因素、征兆、应急救援和信息获取。结果:846人参与问卷调查,其中55%为男性,45%为女性,平均年龄45.7岁。收集数据表明,28%的受调查居民认为高血压是主要的危险因素,头晕(29%)和麻木(20.2%)是中风常见的征兆。所有数据都显示,当中风时人们采取急救措施是有必要的。家庭/朋友(21%)及媒体(电视占19.5%,报纸占17.7%)是中风信息传播的主要途径。结论:应重视推广中国大陆地区有关中风预防的低成本高效率的教育项目,尤其是中风危险因素、征兆、应急处理和信息获取途径的相关项目。开拓多元化的途径,包括开展促进公众健康的活动,通过医疗专家和医疗设施开展健康教育活动向广大民众宣传中风常识和预防措施。 | Zhenyi LI Peng WANG Alice Y M JONES Elizabeth DEAN | 2015 | 康复学报2015，0，2： | 3 |
| 8 | Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement显示文摘 | EM Horwitz K Le Blanc M Dominici I Mueller I Slaper-Cortenbach FC Marini RJ Deans DS Krause A Keating | 2005 | Cytotherapy2005，，5： | 2 |
| 9 | 通过模拟学习最大限度地提高物理治疗的临床实习成效(英文)显示文摘本文描述物理治疗专业和物理治疗入门级教育在中国康复医学教育中的演变,提倡以模拟学习技术(simulation-based learning,SBL)为临床实习生积累经验。与医学专业的学生一样,物理治疗专业学生的教育需要一个结构化的临床教育方案,以确保毕业时具备一定的临床专业能力。SBL多年以来一直是医学、工程以及航空专业的首选教学模式。在物理治疗专业培养方案中,SBL培养临床技能的教学模式已经出现。本文亦论述SBL在物理治疗专业入门级教育中的优势,尤其是使用模拟标准化患者作为核心临床教育内容,为学生进入临床实习做好准备。我们建议中国可以将SBL应用在物理治疗专业人才培养方案中,这能够最大限度地提高学生的临床实习经验。 | Alice Y M JONES Margot A SKINNER Elizabeth DEAN | 2015 | 康复学报2015，25，1： | 2 |
| 10 | Posterior interosseous nerve localization within the proximal forearm-a patient normalized parameter显示文摘AIM To provide a 'patient-normalized' parameter in the proximal forearm. METHODS Sixty-three cadaveric upper extremities from thirty-five cadavers were studied. A muscle splitting approach was utilized to locate the posterior interosseous nerve(PIN) at the point where it emerges from beneath the supinator. The supinator was carefully incised to expose the midpoint length of the nerve as it passes into the forearm while preserving the associated fascial connections, thereby preserving the relationship of the nerve with the muscle. We measured the transepicondylar distance(TED), PIN distance in the forearm's neutral rotation position, pronation position, supination position, and the nerve width. Two individuals performed measurements using a digital caliper with inter-observer and intraobserver blinding. The results were analyzed with the Wilcoxon-Mann-Whitney test for paired samples. RESULTS In pronation, the PIN was within two confidence intervals of 1.0 TED in 95% of cases(range 0.7-1.3 TED); in neutral, within two confidence intervals of 0.84 TED in 95% of cases(range 0.5-1.1 TED); in supination,within two confidence intervals of 0.72 TED in 95% of cases(range 0.5-0.9 TED). The mean PIN distance from the lateral epicondyle was 100% of TED in a pronated forearm, 84% in neutral, and 72% in supination. Predictive accuracy was highest in supination; in all cases the majority of specimens(90.47%-95.23%) are within 2 cm of the forearm position-specific percentage of TED. When comparing right to left sides for TEDs with the signed Wilcoxon-Mann-Whitney test for paired samples as well as a significance test(with normal distribution), the P-value was 0.0357(significance-0.05) indicating a significant difference between the two sides.CONCLUSION This 'patient normalized' parameter localizes the PIN crossing a line drawn between the lateral epicondyle and the radial styloid. Accurate PIN localization will aid in diagnosis, injections, and surgical approaches. | Srinath Kamineni Crystal R Norgren Evan M Davidson Ellora P Kamineni Andrew S Deane | 2017 | World Journal of Orthopedics2017，8，4： | 2 |
| 11 | 寻找抗艾滋病的基因显示文摘 | Dean,M 侯岗 | 1997 | 科学(中文版)1997，，12： | 2 |
| 12 | p38 mitogen-actiated protein kinase regulates cycloxxygenase - 2 mRNA stability and transcription in ipopolysacharide-treated human monocytes显示文摘 | Dean J L Brook M Clark A R | 1999 | J Biol Chen1999，274，： | 1 |
| 13 | Human resource management, manufacturing strategy, and firm performance 显示文摘 | Youndt M A Snell S A Dean J W Lepak D P | 1996 | Academy of Management Journal1996，39，： | 1 |
| 14 | In-vitro testing for assessing oral bioaccessibility of trace metals in soil and food samples显示文摘 | INTAWONGSE M DEAN J R | 2006 | Trends in Analytical Chemistry2006，25，9： | 1 |
| 15 | Tumour stem cells and drug resistance显示文摘 | Dean M Fojo T Bates S | 2005 | Nat Rev Cancer2005，5，： | 1 |
| 16 | The Human ATP- Binding Cassette ( ABC ) Transporter Superfamily 显示文摘 | Dean M Rzhetsky A Allikmets R | 2001 | GENOME RESEARCH2001，11，7： | 1 |
| 17 | The human ATP-binding cassette (ABC) transporter super-family显示文摘 | Dean M Hamon Y Chimini G | 2001 | J Lipid Res2001，42，7： | 1 |
| 18 | The electronic properties of disordered passive films显示文摘 | Dean M H Stimming U | 1989 | Corrosion Science1989，29，16： | 1 |
| 19 | The dimen-sionality of the Maslach Burnout Inventory across small business owners and educators 显示文摘 | BOLES J S DEAN D H XAVIER J M R | 2000 | Journal of Vocational Behavior2000，，： | 1 |
| 20 | Magnetically pro- cessedcarbon nanotube/epoxy nanocomposites: Morpholo- gy, thermal, and mechanical properties显示文摘 | Abdalla M Dean D Theodore M | 2010 | Polymer2010，51，7： | 1 |
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