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| 1 | 从附睾到卵子:CRISP蛋白在哺乳动物受精过程中的作用显示文摘哺乳动物的受精过程涉及精卵结合的很多步骤,是一个非常复杂的过程,其分了机制亟待阐明。此篇综述主要论述了CRISP(富含半胱氨酸的分泌蛋白)作为模型分子在哺乳动物受精过程中的价值。大量的体外实验和基因敲出模型研究显示,附睾内的CRISP1以两种不同的亲和力结合于精子表面,参与精子获能、精子-透明带结合、精卵融合的调控。这些研究成果可以延伸至人类。我们住研究中发现,人类具有与啮齿类同源的CRISP(hCRISP1),同样参与受精过样。CRISP家族的其他成员(睾丸内CRISP2、附挈内CRISP3—4、射精时的CRISP3)也参与了精卵结合的过程,提示同源分子间的相互协同有助于受精的成功。另外,我们的研究显示,CRISP蛋白伴随精子穿越男性及女性生殖管道的全过程。我们推测CRISP不仅参与了受精过程,而且可能成为不育和避孕研究的新靶点。 | Vanina G Da Ros Mariana Weigel Munoz Maria A Battistone Nicolas G Brukman Guillermo Carvajal Ludmila Curci Matlas D Gomez-Elias Debora J Cohen Patricia S Cuasnicu | 2015 | Asian Journal of Andrology2015，17，5： | 5 |
| 2 | Study of the growth process of in situ polyaniline deposited films显示文摘 | Silmar A Travain Nara C de Souza Debora T Balogh | 2007 | Journal of Colloid and Interface Science2007，316，2： | 1 |
| 3 | The utility of p16INK4a and Ki-67 staining on cell blocks prepared from residual thin-layer cervicovaginal, aterial显示文摘 | Ilkser Akpolat Debora A Ibrabim R | 2004 | Cancer2004，102，3： | 1 |
| 4 | Autohydrolysis of agricultural by-products for the production of xylo-oligosaccharides 显示文摘 | Debora N Ebringerova A Montane D | 2007 | Carbohydrate Polymers2007，69，1： | 1 |
| 5 | Oxidative stress parameters in blood, liver, and kidney of diabetic rats treated with curcumin and/or insulin显示文摘 | Heloisa Einloft Palma Patrícia Wolkmer Miguel Gallio Marcos M. B. Corrêa Roberta Schmatz Gustavo R. Thomé Luciane B. Pereira Ver?nica S. P. Castro Andréia B. Pereira Andressa Bueno Lizielle S. Oliveira Debora Rosolen Thaís R. Mann Bianca S. Cecco Domingui | 2014 | 2014 (1-2)2014，，1： | 1 |
| 6 | The ex utero intrapartum treatment( EXIT) pro-cedure for fetal head and neck masses 显示文摘 | Debora F Lourdes A | 2009 | AORN Journal2009，90，5： | 1 |
| 7 | Estrogenic activity removal of 17β-estradiol by ozonation and identification of by-products 显示文摘 | Danlele Bila Antonio F Montalveto Debora de A Azevedo | 2007 | Chemosphere2007，69，5： | 1 |
| 8 | Comparison of intravenous fentanyl analgesia and epidural analgesia for postoperative pain relief显示文摘 | DEBORA H S A JOSEPH C P DAVID K M | 2009 | Masui2009，58，9： | 1 |
| 9 | Low-tem-perature NH3 selective catalytic reduction of NOx over sub-stituted MnCr2 04 spinel-oxide catalysts 显示文摘 | Miguel A Zamudio Nunzio Russo Debora Fino | 2011 | Industrial andEngineering Chemistry Research2011，50，： | 1 |
| 10 | Ef- fects of Pseudomonas putida modified to produce phenazine-1- carboxylic acid and 2,4-diacetylphloroglucinol on the microflo- ra of field grown wheat显示文摘 | PETER A H M B DEBORA C M G MAREIKE V | 2002 | Kluwer Academic Publishers2002，81，： | 1 |
| 11 | A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints显示文摘 | Debora Fumagalli Philippe L Bedard Zeina Nahleh Stefan Michiels Christos Sotiriou Sherene Loi Joseph A Sparano Matthew Ellis Nola Hylton Jo Anne Zujewski Clifford Hudis Laura Esserman Martine Piccart | 2012 | Lancet Oncology2012，，6： | 1 |
| 12 | Study of the growth process of in situ polyaniline deposited films 显示文摘 | Silmar A T Nara C de Souza Debora T B | 2007 | Journal of Colloid and Interface Science2007，316，2： | 1 |
| 13 | Streamwise Vortex Production by Pitched and Skewed Jets in a Turbulent Boundary Layer显示文摘 | Debora A | 1992 | AIAA1992，30，3： | 1 |
| 14 | Tabu search total tardiness minimization in flowshop scheduling problems显示文摘 | Armentano Vinicius A Debora P R | 1999 | Computers & operations research1999，26，3： | 1 |
| 15 | Estrogenic activity removal of 17β-estradiol by ozonation and identification of by-products显示文摘 | Daniele Bila Antonio F Montalvao Debora de A | 2007 | Chemosphere2007，69，： | 1 |
| 16 | Study of antinucTolial activity and atonic force microscopy imaging of the action mechardsm of cashew tree gum显示文摘 | ALEXANDRA C R DEBORA A C EDUARDO M C | 2012 | Carbohydrate Polymers2012，90，： | 1 |
| 17 | Ambi- ent temperature kinetic assessment of biogas production from co-digestion of horse and cow dung显示文摘 | YUSUF M O L DEBORA A OGHENERUONA D E | 2011 | Journal of Agricultural Engineering Research2011，57，3： | 1 |
| 18 | Sodium - calcium exchange: A molecular perspective 显示文摘 | Kenneth D Philipson Debora A Nicoll | 2000 | Annu Rev Physiol2000，62，： | 1 |
| 19 | Temporal distribution behaviour and reactivities of BTEX compounds in a suburban Atlantic area during a year显示文摘 | Debora Perez-Rial Purificacion Lopez-Maha Soledad Muniategui-Lorenzo | 2009 | Journal of Environmental Monitoring2009，11，： | 1 |
| 20 | Association of UBP 1 to ribonucleoprotein complexes is regulated by interaction with the trypanosome ortholog of the human multifunctional P 32 protein显示文摘 | Alejandro Cassola María Albertina Romaniuk Debora Primrose Gabriela Cervini Iván D’Orso Alberto Carlos Frasch | 2015 | Molecular Microbiology2015，，： | 1 |
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