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4篇 您的检索式:作者名="Defu Zhu"
    题名 作者 年代 出处 被引量
1Mechanisms of support failure and prevention measures under double-layer room mining gobs——A case study: Shigetai coal mine显示文摘In the practice of mining shallow buried ultra-close seams,support failure tends to occur during the process of longwall undermining beneath two layers of room mining goaf(TLRMG).In this paper,the factors causing support failure are summarized into geology and mining technology.Combining column lithology and composite beam theory,the key stratum of the rock strata is determined.A finite element numerical simulation is used to analyze the overlying load distribution rule of the main roof for different plane positions of the upper and lower room mining pillars.The tributary area theory(TAT)is adopted to analyze the vertical load distribution of each pillar,and dynamic models of coal pillar instability and main roof fracture are established.Through key block instability analysis,two critical moments are established,of which critical moment A has the greater dynamic load strength.Great economic losses and safety hazards are created by the dynamic load of the fracturing of the main roof.To reduce these negative effects,a method of pulling out supports is developed and two alternative measures for support failure prevention are proposed:reinforcing stope supports in conjunction with reducing mining height,or drilling ground holes to pre-split the main roof.Based on a comprehensive consideration of economic factors and the two categories of support failure causes,the method of reinforcing stope supports while reducing mining height was selected for use on the mining site.Defu Zhu Shihao Tu Hongsheng Tu Zhenqian Yang 2019International Journal of Mining Science and Technology2019,29,6:4
2Clinical Significance of Preoperative Nutritional Risk Screening and Support in the Perioperative Period of Gastric Cancer Patients显示文摘Objective:To investigate the clinical value of using preoperative nutritional risk screening and support in gastric cancer patients.Methods:In this paper,70 gastric cancer patients selected from July 2017 to July 2020 treated in our hospital were grouped concerning the lottery method,and the reference group(n=35)used conventional nutritional support,while the experimental group(n=35)used preoperative dietary risk screening and support,comparing the clinical treatment differences between gastric cancer patients in the experimental group and the reference group.Results:After the intervention,IgA,IgM,IgG,serum albumin,complication rate,NRS score,hospitalization time and anal exhaust time of gastric cancer patients in the experimental group were compared with those in the reference group,P<0.05,and there was statistical validation analysis significance between the data indicators.P<0.05 for the comparison of IgA,IgM,IgG,serum albumin after the intervention and pre-intervention for gastric cancer patients in the experimental group and the reference group,with statistical validation analysis significance between the data indicators.Conclusion:Preoperative nutritional risk screening and support is of significant value in gastric cancer patients and can improve patients’nutritional status.Defu Tian Chao Yin Bing Ren Puli Zhu 2020Proceedings of Anticancer Research2020,4,5:0
3Oral administration of Moringa oleifera leaf powder relieves oxidative stress,modulates mucosal immune response and cecal microbiota after exposure to heat stress in New Zealand White rabbits显示文摘Background:Heat stress(HS)disrupts the gut barrier allowing the uptake of lipopolysaccharide(LPS)and leads to an inflammatory response and changes in gut microbiota composition.Moringa oleifera leaf powder(MOLP)has been proposed to combat HS,yet its alleviate role is currently under investigation.The current study investigated the effects of chronic HS and MOLP supplementation on changes in redox status and immune response of cecal mucosa along with alteration in cecal microbiota.Methods:A total of 21 young New Zealand White(NZW)rabbits(male)about 32 weeks old(mean body weight of 3318±171 g)reared on a commercial pelleted diet were employed;divided into three groups(n=7):control(CON,25°C),heat stress(HS,35°C for 7 h daily),and HS supplemented orally with MOLP(HSM,35°C)at 200 mg/kg body weight per day for 4 weeks.Results:The results demonstrated that MOLP supplementation increased organ index of cecal tissue compared with the HS group(P>0.05).Levels of malonaldehyde(MDA)and activity of superoxide dismutase(SOD)as well as lactate dehydrogenase(LDH)were reduced in the cecal mucosa of the HSM group compared with the HS group.MOLP downregulated the contents of cecal mucosa LPS,several inflammatory markers(TNF-α/IL-1α/IL-1β),and myeloperoxidase(MPO)in the HSM group(P<0.05).Secretory immunoglobulin A(SIgA)was increased in the HSM group compared with the HS group(P<0.05).The transcriptome of cecal mucosa showed that MOLP reduced gene expression relative to several immune factors,including IL-10,IFNG,and RLA,whereas both HS and MOLP increased the gene expression of fat digestion and absorption pathway,including APOA1,FABP1,FABP2,MTTP,andLOC100344166,compared to the CON group(P<0.001).At the phylum level,the relative abundance of Proteobacteria was increased by HS,while Actinobacteria was significantly increased by HSM compared to other groups(P<0.05).At genus level,Papillibacter was higher in abundance in HSM groups compared to CON and HS groups(P<0.05).Higher butyrate concentrations were observed in the HSM group than HS and CON groups(P<0.05).Conclusion:In conclusion,HS in growing rabbits resulted in alteration of cecal microbiota at phyla level as well as increased oxidative stress and expression of mucosal inflammatory genes.Whereas,oral MOLP supplementation elevated the relative weight of cecum,affected their immunological and cecal micro-ecosystem function by improving antioxidant status and down-regulating mucosal tissue inflammatory response.Talat Bilal Yasoob Defu Yu Abdur Rauf Khalid Zhen Zhang Xiaofeng Zhu Heba M.Saad Suqin Hang 2021Journal of Animal Science and Biotechnology2021,12,4:0
4抗氧化和长期抗菌活性迷迭香酸明胶生物降解膜的研制显示文摘开发新的方法将天然活性物质加入到凝胶基的食用薄膜中,以获得有效的抗氧化和长期的抗菌活性,具有重要的意义.在这里,天然活性化合物迷迭香酸(RosA)首先通过EDC/NHS化学结合在明胶骨架上.然后用甘油偶联物进行塑化,并与二醛黄原胶交联,制备活性RosA-明胶食用薄膜.结果表明,该食品膜具有良好的耐水性能、较强的力学性能和较好的紫外光阻隔性能.RosA的共轭使以明胶为基础的可食用薄膜具有预期的有效抗氧化和抗菌活性.有趣的是,经过3个月的贮藏后,RosA-明胶食用膜仍具有较好的抗菌活性,显示出较长期的抗菌活性.总之,所制备的RosA-明胶食用薄膜在食品和医药包装领域具有广阔的应用前景.Liming Ge Mingjin Zhu Xinying Li Yongbin Xu Xiaonan Ma Rong Shi Defu Li Changdao Mu 2018绿色包装2018,0,7:0
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