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| 1 | A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity显示文摘由调整 transcriptional 激活剂 Yorkie (Yki ) 的活动的河马(Hpo ) 小径控制织物生长和机关尺寸,它在原子核与抄写因素 Scalloped (Sd ) 联系下游地支持指向基因表示。这里,我们识别新奇蛋白质 Sd-Binding-Protein (SdBP )/Tgi,它直接通过它的 TDU 域为绑定与 Yki 竞争到 Sd 并且禁止 Sd-Yki transcriptional 活动。我们也发现 SdBP 经由它的 PPXY 主题与 Yki WW 领域通过协会在原子核保留 Yki。一起,我们作为 Hpo 小径的一个新奇部件识别 SdBP,否定地调整 Sd-Yki 的 transcriptional 活动限制织物生长。 | Tong Guo Yi Lu Peixue Li Meng-Xin Yin Dekang Lv Wenjing Zhang Huizhen Wang Zhaocai Zhou Hongbin Ji Yun Zhao Lei Zhang | 2013 | Cell Research2013，23，10： | 13 |
| 2 | Active catalysts based on cobalt oxide@cobalt/N-C nanocomposites for oxygen reduction reaction in alkaline solutions显示文摘 | Dekang Huang Yanping Luo Shaohui Li Bingyan Zhang Yan Shen Mingkui Wang | 2014 | Nano Research2014，7，7： | 8 |
| 3 | SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation显示文摘Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is the ongoing global pandemic that poses substantial challenges to public health worldwide.A subset of COVID-19 patients experience systemic inflammatory response,known as cytokine storm,which may lead to death.Receptor-interacting serine/threonine-protein kinase 1(RIPK1)is an important mediator of inflammation and cell death.Here,we examined the interaction of RIPK1-mediated innate immunity with SARS-CoV-2 infection.We found evidence of RIPK1 activation in human COVID-19 lung pathological samples,and cultured human lung organoids and ACE2 transgenic mice infected by SARS-CoV-2.Inhibition of RIPK1 using multiple smallmolecule inhibitors reduced the viral load of SARS-CoV-2 in human lung organoids.Furthermore,therapeutic dosing of the RIPK1 inhibitor Nec-1s reduced mortality and lung viral load,and blocked the CNS manifestation of SARS-CoV-2 in ACE2 transgenic mice.Mechanistically,we found that the RNA-dependent RNA polymerase of SARS-CoV-2,NSP12,a highly conserved central component of coronaviral replication and transcription machinery,promoted the activation of RIPK1.Furthermore,NSP12323L variant,encoded by the SARS-CoV-2 C14408T variant first detected in Lombardy,Italy,that carries a Pro323Leu amino acid substitution in NSP12,showed increased ability to activate RIPK1.Inhibition of RIPK1 downregulated the transcriptional induction of proinflammatory cytokines and host factors including ACE2 and EGFR that promote viral entry into cells.Our results suggest that SARS-CoV-2 may have an unexpected and unusual ability to hijack the RIPK1-mediated host defense response to promote its own propagation and that inhibition of RIPK1 may provide a therapeutic option for the treatment of COVID-19. | Gang Xu Ying Li Shengyuan Zhang Haoran Peng Yunyun Wang Dekang Li Taijie Jin Zhuohao He Yilun Tong Chunting Qi Guowei Wu Kangyun Dong Jizhou Gou Yang Liu Tongyang Xiao Jing Qu Liang Li Liang Liu Ping Zhao Zheng Zhang Junying Yuan | 2021 | Cell Research2021，31，12： | 6 |
| 4 | Phase control system for SSRF linac显示文摘The design of phase control system in Shanghai Synchrotron Radiation Facility (SSRF) linac is presented in this paper. And digital phase detecting algorithm, the key for phase control system, is fully described. The testing results for phase control system in 100MeV linac are discussed in detail. | YIN Chongxian YU Luyang LIU Dekang | 2008 | Nuclear Science and Techniques2008，19，3： | 4 |
| 5 | Rational holomorphic maps from B^2 into B^N with degree 2显示文摘Rational proper holomorphic maps from the unit ball in C2 into the unit ball CN with degree 2 are studied. Any such map must be equivalent to one of the four types of maps. | CHEN Zhihua, Jl Shanyu & XU Dekang Department of Mathematics, Tongji University, Shanghai 200092, China Department of Mathematics, University of Houston, Houston, TX 77204, USA | 2006 | Science China Mathematics2006，49，11： | 3 |
| 6 | Host cell apoptosis induced by infection with duck swollen head hemorrhagic disease virus显示文摘This study aimed to examine the host cell apoptosis in the tissues of Peking ducks infected with duck swollen head hemorrhagic disease virus(DSHDV).The dynamic changes associated with apoptosis occurring in the internal tissues were evaluated at different time points postinoculation(PI) by performing hematoxylin and eosin(HE) staining,followed by light microscopy,terminal deoxynucleotidyl transferase dUTP nick-end labeling(TUNEL) assay,and transmission electron microscopy(TEM).The results showed that DSHDV infection could induce apoptosis in host cells,including those of the bursa of Fabricius(BF),thymus,spleen,liver,intestinal tract,kidney,and esophagus.The apoptotic index(AI) values increased with time from 2 to 72 h PI,and the highest values were recorded at 72 h PI.Further,cell death due to classic necrosis was observed in the dying or deceased ducks after 72 h PI.In conclusion,host cell apoptosis can be induced by DSHDV and may play an important role in the pathogenesis of duck viral swollen head hemorrhagic disease(DVSHD). | Chuanfeng Li Anchun Cheng Mingshu Wang Chanjuan Shen Na Zhang Yi Zhou Dekang Zhu Qihui Luo Renyong Jia Xiaoyue Chen | 2009 | Progress in Natural Science:Materials International2009，19，1： | 3 |
| 7 | Synchrotrons radiation stability measurement and improvement显示文摘In the 3rd generation synchrotron light source,beside the orbit,air disturbance and ground vibration also could affect the position stability of photon beam in synchrotrons radiation measurement.In the condition of implementation of orbit feedback system at SSRF,the measured position stability of photon beam in synchrotrons radiation measurement station was presented in this paper.And then the improvement methods of position stability of photon beam were discussed.Finally the measured result was shown when the designed feedback system is implemented to improve the position stability of photon beam. | Tang Siwei Yin Chongxian Liu Dekang | 2012 | Nuclear Science and Techniques2012，23，1： | 2 |
| 8 | High-performance modified uni-traveling carrier photodiode integrated on a thin-film lithium niobate platform显示文摘Lithium niobate on insulator(LNOI)has become an intriguing platform for integrated photonics for applications in communications,microwave photonics,and computing.Whereas,integrated devices including modulators,resonators,and lasers with high performance have been recently realized on the LNOI platform,high-speed photodetectors,an essential building block in photonic integrated circuits,have not been demonstrated on LNOI yet.Here,we demonstrate for the first time,heterogeneously integrated modified uni-traveling carrier photodiodes on LNOI with a record-high bandwidth of 80 GHz and a responsivity of 0.6 A/W at a 1550-nm wavelength.The photodiodes are based on an n-down In GaAs/InP epitaxial layer structure that was optimized for high carrier transit time-limited bandwidth.Photodiode integration was achieved using a scalable wafer die bonding approach that is fully compatible with the LNOI platform. | XIANGWEN GUO LINBO SHAO LINGYAN HE KEVIN LUKE JESSE MORGAN KEYE SUN JUNYI GAO TA-CHING TZU YANG SHEN DEKANG CHEN BINGTIAN GUO FENGXIN YU QIANHUAN YU MASOUD JAFARI MARKO LONčAR MIAN ZHANG ANDREAS BELING | 2022 | Photonics Research2022，10，6： | 2 |
| 9 | Spatial Patterns of LULC and Driving Forces in the Transnational Area of Tumen River:A Comparative Analysis of the Sub-regions of China,the DPRK,and Russia显示文摘Understanding the spatial patterns of land-use and land-cover(LULC)and their driving forces in transnational areas is important for the sustainable development of these regions.However,the spatial patterns of LULC and their driving forces across multiple scales are poorly understood in transnational areas.In this study,we analyzed the spatial patterns of LULC and driving forces in the transnational area of Tumen River(TATR)in 2016 across two scales:the entire region and the sub-regions of China,the Democratic People’s Republic of Korea(DPRK),and Russia.Results showed that the LULC was dominated by broadleaf forest and dry farmland in the TATR in 2016,which accounted for 66.86%and 13.60%of the entire region,respectively.Meanwhile,the LULC in the three sub-regions exhibited noticeable differences.In the Chinese and the DPRK’s sub-regions,the area of broadleaf forest was greater than those for the other LULC types,while the Russian sub-region was dominated by broadleaf forest and grassland.The spatial patterns of LULC were mainly influenced by topography,climate,soil properties,and human activities.In addition,the driving forces of the spatial patterns of LULC in the TATR had an obvious scaling effect.Therefore,we suggest that effective policies and regulations with cooperation among China,the DPRK,and Russia are needed to plan the spatial patterns of LULC and improve the sustainable development of the TATR. | NAN Ying WANG Bingbing ZHANG Da LIU Zhifeng QI Dekang ZHOU Haohao | 2020 | Chinese Geographical Science2020，30，4： | 2 |
| 10 | Numerical Method Satisfying the First Two Conservation Laws for zhe Korteweg-de Vries Equation显示文摘 | Cui Yanfen Mao Dekang | | 0，，01： | 1 |
| 11 | Numericallyneither dissipative nor compressive scheme for linearadvection equation and its Application to the Euler Sys-tem显示文摘 | Li Hongxia Wang Zhigang Mao Dekang | | 0，，03： | 1 |
| 12 | Numerical method satisfyingthe first two conservation laws for the Korteweg-de Vriesequation显示文摘 | Cui Yanfen Mao Dekang | | 0，，01： | 1 |
| 13 | error self-canceling of adifference scheme maintaining two conservation lawsfor linear advection equation显示文摘 | Cui Yanfen Mao Dekang | | 0，，： | 1 |
| 14 | Therapeutic effect of human umbilical cord mesenchymal stem cells on neonatal rat hypoxic–ischemic encephalopathy显示文摘 | Xinhua Zhang Qinfen Zhang Wei Li Dekang Nie Weiwei Chen Chunxiang Xu Xin Yi Jinhong Shi Meiling Tian Jianbing Qin Guohua Jin Wenjuan Tu | 2014 | Journal of Neuroscience Research2014，，1： | 1 |
| 15 | A Statistical Corpus-Based Term Extractor 显示文摘 | Patrick Pantel Dekang Lin | 2001 | Canadian Conferemce on AI2001，2001，： | 1 |
| 16 | Free- standing bacterial cellulose-polypyrrole nanofibres paper electrodes for advanced energy storage devices 显示文摘 | Li Shaohui Huang Dekang Yang Junchuan | 2014 | Nano Energy2014，4，： | 1 |
| 17 | Rigidity of the proper self-mapping on some kinds generalized hartogs triangles显示文摘 | XU Dekang | 2002 | Acta Mathematica Sinica English Sense2002，18，2： | 1 |
| 18 | Spatial patterns of net primary productivity and its driving forces:a multi-scale analysis in the transnational area of the Tumen River显示文摘Analyzing the spatial patterns of net primary productivity(NPP)and its driving forces in transnational areas provides a solid basis for understanding regional ecological processes and ecosystem services.However,the spatial patterns of NPP and its driving forces have been poorly understood on multiple scales in transnational areas.In this study,the spatial patterns of NPP in the transnational area of the Tumen River(TATR)in 2016 were simulated using the Carnegie Ames Stanford Approach(CASA)model,and its driving forces were analyzed using a stepwise multiple linear regression model.We found that the total amount of NPP in the TATR in 2016 was approximately 14.53 TgC.The amount of NPP on the Chinese side(6.23 TgC)was larger than those on the other two sides,accounting for 42.88%of the total volume of the entire region.Among different land-use and land-cover(LULC)types,the amount of NPP of the broadleaf forest was the largest(11.22 TgC),while the amount of NPP of the bare land was the smallest.The NPP per unit area was about 603.21 gC/(m2 yr)across the entire region,while the NPP per unit area on the Chinese side was the largest,followed by the Russian side and the DPRK's side.The spatial patterns of NPP were influenced by climate,topography,soil texture,and human activities.In addition,the driving forces of the spatial patterns of NPP in the TATR had an obvious scaling effect,which was mainly caused by the spatial heterogeneity of climate,topography,soil texture,and human activities.We suggest that effective land management policies with cooperation among China,the DPRK,and Russia are needed to maintain NPP and improve environmental sustainability in the TATR. | Jianwen WANG Da ZHANG Ying NAN Zhifeng LIU Dekang QI | 2020 | Frontiers of Earth Science2020，14，1： | 1 |
| 19 | Discovery of Inference Rules for Question-answering显示文摘 | Lin Dekang Pantel P | 2001 | Natural Language Engineering2001，7，4： | 1 |
| 20 | Underpressure of Vaporization of refrigerant R- 134a through adiabatic apillary tube显示文摘 | Dekang Chen Sui Lin | 2001 | International Journal of Refrigeration2001，24，： | 1 |
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