维普中文期刊产品整合服务
345篇 您的检索式:作者名="Desideri"
    题名 作者 年代 出处 被引量
1Overexpression of microRNA-145 in atherosclerotic plaques from hypertensive patients显示文摘Donato Santovito Claudia Mandolini Pamela Marcantonio Velia De Nardis Marco Bucci Camilla Paganelli Francesco Magnacca Sante Ucchino Daniela Mastroiacovo Giovambattista Desideri Andrea Mezzetti Francesco Cipollone 2012Expert Opinion on Therapeutic Targets2012,,3:2
2CYP3A4介导的睾酮和卡马西平与香芹酚的相互作用显示文摘目的考察香芹酚对细胞色素P450酶3A4(CYP3A4)介导的睾酮6β羟化反应和卡马西平10,11环氧化反应的抑制作用。方法人肝微粒体与香芹酚(或阳性对照酮康唑)、探针底物(睾酮或卡马西平)在37℃下孵育一定的时间。液相色谱二极管阵列法测定探针底物代谢物生成速率。探针底物在米氏常数(Km)浓度下,单点法检测抑制剂活性,多点法测定测定半数抑制浓度(IC50),抑制动力学法测定抑制常数(Ki)。结果香芹酚是CYP3A4介导的卡马西平10,11环氧化反应的非竞争性抑制剂,IC50为(15.3±1.4)μmol·L-1,Ki为(14.1±1.0)μmol·L-1。但香芹酚对CYP3A4介导的睾酮6β-羟化反应无抑制作用。酮康唑1μmol·L-1几乎完全抑制CYP3A4介导的睾酮6β-羟化反应和卡马西平10,11环氧化反应。结论香芹酚对CYP3A4的抑制存在底物依赖性,提示香芹酚与卡马西平联合用药可能存在风险。李洋 George Desideri KASHANGAKI 衣服新 2020中国药理学与毒理学杂志2020,34,8:2
3Plutonium and americium determination in mosses by laser ablation ICP-MS combined with isotope dilution technique显示文摘BOULYGA S F DESIDERI D MELI M A 2003International Journal of Mass Spec- trometry2003,226,:1
4Effects of left bundle branch block on myocardial FDG PET in patients without significant coronary ar- tery stenoses显示文摘Zanco P Desideri A Mobilia G 2000J Nucl Med2000,41,:1
5Nasal ventilation in-COPD exacerbations:early and late result s of a prospective,controlled study显示文摘Bardi G Pierotello R Desideri M 2000Eur Respir J2000,15,1:1
6Preprocedural level of soluble CD40L is predictive of enhanced inflammatory response and restenosis after coronary angioplasty显示文摘Cipollone F Ferri C Desideri G 2003Circulation2003,108,22:1
7Metabolic management of ischemic heart disease,clinical data with trimetazidine显示文摘Desideri A Celegonl 0,,05:1
8Nasal ventilation in COPD exacerbations:early and late results of a prospective,controlled study显示文摘Bardi G Pierotello R Desideri M 2000Eur Respir J2000,15,1:1
9Carotid ultrasound assessment of patients with coronary artery disease:a useful index for risk stratification显示文摘Komorovsky R Desideri A 0,,02:1
10Metabolic management of ischemic heart disease: Clinical data with trimetazidine显示文摘Desideri A Celegon L 1998Am J Cardiol1998,82,5:1
11Functional activity of CXCL8 receptors, CXCR1 and CXCR2, on human malignant melanoma progression显示文摘Chiara Gabellini Daniela Trisciuoglio Marimma Desideri 2009Eur J Cancer2009,45,:1
12Role of combination therapy in the treatment of hypertension: focus on valsartan plus amlodipine显示文摘FERRI C CROCE G Desideri G 2008Adv Ther2008,25,4:1
13Functional activity of CXCL8 receptors,CXCR1 and CXCR2,on human malignant Melanoma progression显示文摘Gabellini C Trisciuoglio D Desideri M 2009Eur J Cancer2009,45,14:1
14Elective surgery for giant bullous emphysema: a 52-year clinical and functional follow-up 显示文摘Palla A Desideri M Rossi G 2005Chest2005,128,4:1
15Highly efficient electricity through a hybrid molten carbonate fuel cell-closed loop gas turbine plant显示文摘Piero Lunghi Stefano Ubertini Umberto desideri 2001Energy Conversion and Management2001,,42:1
16Nasal Ventilation in COPD Exacerbations:Early and Late Results of a Prospective, Controlledstudy显示文摘Bardi G Pierotello R Desideri M 2000Eur Respir J2000,15,1:1
17Functional activityof CXCL8 receptors, CXCR1 and CXCR2, on human malignantmelanoma progression 显示文摘Gabellini C Trisciuoglio D Desideri M 2009Eur J Cancer2009,45,14:1
18Sticholysin II: A pore-forming toxin as a probe to recognize sphingomyelin in artificial and cellular membranes显示文摘Paloma Sanchez Garcia Gabriele Chieppa Alessandro Desideri Stefano Cannata Elena Romano Paolo Luly Stefano Rufini 2012Toxicon2012,,5:1
19Metabolic management of ischemic heart disease: clinical data with trimetazidine显示文摘 Celegon L 1998Am J Cardiol1998,82,5:1
20Metabolic management of ischemic heart disease:clinical data with trimetazidine显示文摘Desideri A Celegon L 1998Am J Cardiol1998,82,5:1
返回顶部 每页显示:
共18页 首页 上一页 第1页 下一页 末页 /18 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费