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| 1 | Geological Characteristics and Ore-forming Time of the Dexing Porphyry Copper Ore Mine in Jiangxi Province显示文摘The Dexing porphyry copper ore mine is located in the Qin-Hang metallogenic belt between the Yangtze block and the Cathaysia block. It is a giant porphyry copper mine in China, including 3 ore districts: Tongchang, Fujiawu and Zhushahong. Our analyses of Re in molybdenite indicate that the ore-forming material of the copper ore deposits in Dexing should be mainly mantle-derived. Our study fills in a gap in the study of formation time of the Dexing copper mine, and further proves that the copper ore deposits in the three ore districts should be formed simultaneously, about 170 Ma, belonging to the early Yanshan period, and that the formation time of the copper ore deposits should be consistent with the formation time of granodiorite porphyry in which the copper ore deposits are hosted. Promising areas for seeking porphyry copper ore deposits is predicated to be the west or southwest of Dexing. | GUO Shuo ZHAO Yuany QU Huanchun WU Dexin XU Hong LI Chao LIU Yan ZHU Xiaoyun WANG Zengke | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 28 |
| 2 | Single-shot BOTDA based on an optical chirp chain probe wave for distributed ultrafast measurement显示文摘Brillouin optical time-domain analysis(BOTDA)requires frequency mapping of the Brillouin spectrum to obtain environmental information(e.g.,temperature or strain)over the length of the sensing fiber,with the finite frequencysweeping time-limiting applications to only static or slowly varying strain or temperature environments.To solve this problem,we propose the use of an optical chirp chain probe wave to remove the requirement of frequency sweeping for the Brillouin spectrum,which enables distributed ultrafast strain measurement with a single pump pulse.The optical chirp chain is generated using a frequency-agile technique via a fast-frequency-changing microwave,which covers a larger frequency range around the Stokes frequency relative to the pump wave,so that a distributed Brillouin gain spectrum along the fiber is realized.Dynamic strain measurements for periodic mechanical vibration,mechanical shock,and a switch event are demonstrated at sampling rates of 25 kHz,2.5 MHz and 6.25 MHz,respectively.To the best of our knowledge,this is the first demonstration of distributed Brillouin strain sensing with a wide-dynamic range at a sampling rate of up to the MHz level. | Dengwang Zhou Yongkang Dong Benzhang Wang Chao Pang Dexin Ba Hongying Zhang Zhiwei Lu Hui Li Xiaoyi Bao | 2018 | Light(Science & Applications)2018，7，1： | 11 |
| 3 | Geochronology, Geochemistry and Sr-Nd-Pb-Hf Isotopes of No. I Complex from the Shitoukengde Ni–Cu Sulfide Deposit in the Eastern Kunlun Orogen, Western China: Implications for the Magmatic Source, Geodynamic Setting and Genesis显示文摘The Shitoukengde Ni-Cu deposit, located in the Eastern Kunlun Orogen, comprises three mafic–ultramafic complexes, with the No. I complex hosting six Ni-Cu orebodies found recently. The deposit is hosted in the small ultramafic bodies intruding Proterozoic metamorphic rocks. Complexes at Shitoukengde contain all kinds of mafic-ultramafic rocks, and olivine websterite and pyroxene peridotite are the most important Ni-Cu-hosted rocks. Zircon U-Pb dating suggests that the Shitoukengde Ni-Cu deposit formed in late Silurian(426–422 Ma), and their zircons have εHf(t) values of-9.4 to 5.9 with the older T_(DM1) ages(0.80–1.42 Ga). Mafic-ultramafic rocks from the No. I complex show the similar rare earth and trace element patterns, which are enriched in light rare earth elements and large ion lithophile elements(e.g., K, Rb, Th) and depleted in heavy rare earth elements and high field strength elements(e.g., Ta, Nb, Zr, Ti). Sulfides from the deposit have the slightly higher δ^(34)S values of 1.9–4.3‰ than the mantle(0 ± 2‰). The major and trace element characteristics, and Sr-Nd-Pb and Hf, S isotopes indicate that their parental magmas originated from a metasomatised, asthenospheric mantle source which had previously been modified by subduction-related fluids, and experienced significant crustal contamination both in the magma chamber and during ascent triggering S oversaturation by addition of S and Si, that resulted in the deposition and enrichment of sulfides. Combined with the tectonic evolution, we suggest that the Shitoukengde Ni-Cu deposit formed in the post-collisional, extensional regime related to the subducted oceanic slab break-off after the Wanbaogou oceanic basalt plateau collaged northward to the Qaidam Block in late Silurian. | LI Liang SUN Fengyue LI Bile LI Shijin CHEN Guangjun WANG Wei YAN Jiaming ZHAO Tuofei DONG Jun ZHANG Dexin | 2018 | Acta Geologica Sinica(English Edition)2018，92，1： | 10 |
| 4 | Correlation of the temporal and spatial expression patterns of HQT with the biosynthesis and accumulation of chlorogenic acid in Lonicera japonica flowers显示文摘Hydroxycinnamoyl-CoA quinate transferase(HQT)is one of the key enzymes in the biosynthesis of chlorogenic acid(CGA)in the flowers of Lonicera japonica.However,the spatiotemporal expression patterns of HQT and its relationship to the dynamics of CGA biosynthesis,transport,and storage remain largely unknown.In this study,we collected L.japonica flower samples at different growth stages(S1–S6)and examined the spatiotemporal expression pattern of HQT and the dynamic accumulation patterns of CGA using a combination of molecular and cytological techniques.Our results suggest that the spatiotemporal expression pattern of HQT is directly correlated with dynamic changes in CGA accumulation and distribution in L.japonica flowers.We further show that CGA is synthesized primarily in the cytoplasm and chloroplasts.CGA synthesized in the cytoplasm first accumulates in specialized vesicles and is then transferred to large central vacuoles for storage by fusion of CGA-containing vesicles with vacuoles.Furthermore,CGA synthesized in the chloroplasts appears to be transferred into the vacuoles for storage by direct membrane fusion between the tonoplast and the disrupted chloroplast membranes.Collectively,our results suggest that CGA is synthesized in chloroplasts and cytoplasm and finally transferred to the vacuole for long-term storage. | Yanqun Li Dexin Kong Mei Bai Hanjun He Haiyang Wang Hong Wu | 2019 | Horticulture Research2019，6，1： | 7 |
| 5 | Validity and reliability of Chinese version of Fatigue Impact Scale in cerebral infarction patients显示文摘BACKGROUND: Post-stroke fatigue has received much attention recently. Three evaluation scales are available,including the Fatigue Impact Scale (FIS). Yet none of these has been proven to be of use in the evaluation of psychological quality after post-stroke fatigue. OBJECTIVE: To introduce FIS into China,and to evaluate the validity and reliability of the Chinese Version in patients with cerebral infarction. DESIGN: Scale evaluation. SETTING: Department of Rehabilitation,Beijing Friendship Hospital,Capital Medical University. PARTICIPANTS: A total of 330 patients with cerebral infarction were selected from the Department of Neurology,Beijing Friendship Hospital,Capital Medical University from June 2005 to December 2006. All patients met diagnostic standards from the Fourth National Cerebrovascular Disease Academic Meeting of China Medical Association and were diagnosed with CT or MRI examination. Patients who were not willing to accept scale evaluation were excluded. METHODS: The English version of FIS was translated into Chinese and subsequently translated back to English again. FIS was given to the discharged patients,and they returned them upon completion. In-patients completed and immediately returned the FIS. Validity and reliability of the retrieved scales were ascertained with descriptive and inference analysis. MAIN OUTCOME MEASURES: Total scores and subscale scores of FIS. RESULTS: Out of 330 questionnaires,214 valid questionnaires were deemed valid in total. Six components were extracted in factor analysis,and the total cumulative contribution was 73.919%,which suggested the questionnaire was valid. After correlation analysis,6 components were divided into 3 subscales,including cognitive,physical,and social,which was the same as the English version. The Cronbach α value for the three subscales was 0.937 7,0.918 8,and 0.940 6,respectively (> 0.7). CONCLUSION: The reliability and validity of the Chinese version of FIS met with satisfaction and ap-peared to be adaptable to cerebral infarction patients in China. | Chunwei Wu Zhandong Liu Yongbo Zhang Jimei Li Dexin Wang | 2008 | Neural Regeneration Research2008，3，2： | 6 |
| 6 | Hemorrhagic Fever with Renal Syndrome — Liaoning Province, China, 1999−2018显示文摘Summary What is already known on this topic?Hemorrhagic fever with renal syndrome(HFRS)is endemic in Liaoning Province.Both Seoul and Hantaan virus are circulating in rodents,and epidemic outbreaks and sporadic cases have been recorded every year since the disease was recognized. | Cui Shang Yingwei Sun Qiangling Yin Xiaoxia Huang Xuesheng Liu Quanfu Zhang Lingling Mao Chuan Li Aqian Li Qin Wang Lina Sun Mifang Liang Shiwen Wang Dexin Li Jiandong Li | 2020 | China CDC weekly2020，2，20： | 6 |
| 7 | Anoxic degradation of nitrogenous heterocyclic compounds by activated sludge and their active sites显示文摘The potential for degradation of five nitrogenous heterocyclic compounds(NHCs), i.e.,imidazole, pyridine, indole, quinoline, and carbazole, was investigated under anoxic conditions with acclimated activated sludge. Results showed that NHCs with initial concentration of 50 mg/L could be completely degraded within 60 hr. The degradation of five NHCs was dependent upon the chemical structures with the following sequence:imidazole > pyridine > indole > quinoline > carbazole in terms of their degradation rates.Quantitative structure–biodegradability relationship studies of the five NHCs showed that the anoxic degradation rates were correlated well with highest occupied molecular orbital.Additionally, the active sites of NHCs identified by calculation were confirmed by analysis of intermediates using gas chromatography and mass spectrometry. | Peng Xu Hongjun Han Haifeng Zhuang Baolin Hou Shengyong Jia Dexin Wang Kun Li Qian Zhao | 2015 | Journal of Environmental Sciences2015，27，5： | 5 |
| 8 | Surface crack imaging based on delayed temperature difference at symmetric points by laser spot thermography显示文摘Laser spot thermography is a novel technique for the detection of surface cracks with a laser to heat sample locally and with an IR camera to record the surface temperature distribution. Common methods to characterize cracks are only suitable for the situation that the laser scanning path is vertical to the crack. But due to the randomness of cracks,when the scanning path is parallel to the crack,surface cracks cannot be detected by these methods. To tackle this problem,a method is presented which is suitable for the situation that the scanning path is parallel to crack. The main idea is to evaluate the crack-caused asymmetries of the surface temperature distribution. The effect of temperature gradient and the maximum scanning interval are analyzed by a 2D simulation. A new crack imaging technique is presented that is based on delayed temperature difference at symmetric points to characterize the crack in the thermal image. Compared well with those obtained by the spatial first derivative method,experimental results are shown to efficiently prove this method. | WANG Xiaona WANG Xiaoning HOU Dexin YE Shuliang | 2014 | Instrumentation2014，1，2： | 5 |
| 9 | High-performance optical chirp chain BOTDA by using a pattern recognition algorithm and the differential pulse-width pair technique显示文摘Optical chirp chain Brillouin optical time-domain analysis(OCC-BOTDA) has the capabilities of fast measurement, high Brillouin threshold, and freedom from the nonlocal effect;at the same time, however, it also has problems introduced by transient stimulated Brillouin scattering. The influence of the transient interaction is reflected as the broadened asymmetric Brillouin spectrum, the ghost peak, and the frequency shift of the main peak. This introduces difficulty in computing the fiber Brillouin frequency shift with good measurement accuracy. Besides, the OCC modulation causes additional noise due to the uneven amplitude response for different frequency components. In this work, we propose a high-performance OCC-BOTDA using the principal component analysis(PCA) based pattern recognition algorithm and differential pulse-width pair(DPP) technique.After building the Brillouin spectrum database(i.e., all patterns), the fiber intrinsic Brillouin frequency shift can be recognized by the PCA algorithm from a nonstandard Brillouin spectrum profile, resulting in good measurement accuracy. Meanwhile, the DPP technique, subtracting between two Brillouin signals generated by two wide-width pump pulses, is utilized to reduce the OCC modulation noise and avoid the pulse self-phase modulation effect in long-range BOTDA sensing. In the experiment, a temperature measurement with 1.3 MHz measurement precision, 4 m spatial resolution, and 5 s measurement time is achieved over a 100 km single-mode fiber. | BENZHANG WANG BAOHUA FAN DENGWANG ZHOU CHAO PANG YUE LI DEXIN BA YONGKANG DONG | 2019 | Photonics Research2019，7，6： | 5 |
| 10 | Photosynthesis-transpiration coupling model at canopy scale in terrestrial ecosystem显示文摘At the hypothesis of big leaf, an ecosystem photosynthesis-transpiration coupling cycle model was established by the scaled SMPT-SB model from single leaf to canopy, and model parameterization methods were discussed. Through simulating the canopy light distribution, canopy internal conductance to CO2 can be scaled from single leaf to canopy by integrating to canopy using the relationship between single internal conductance and photosynthetic photon flux density. Using the data observed by eddy covariance method from the Changbai Mountains site of ChinaFLUX, the application of the model at the canopy scale was examined. Under no water stress, the simulated net ecosystem photosynthesis rate fitted with the observed data very well, the slope and R2 of the line regression equation of the observed and simulated values were 0.7977 and 0.8892, respectively (n = 752), and average absolute error was 3.78 μmol CO2 m-2s-1; the slope, R2 and average absolute error of transpiration rate were 0.7314, 0.4355 and 1.60mmol H2O m-2 s-1, respectively (n = 752). The relationship between canopy photosynthesis,transpiration and external environmental conditions was discussed by treating the canopy as a whole and neglecting the comprehensive feedback mechanism within canopy, and it was noted that the precipitation course affected the transpiration rate simulation badly. Compared to the models based on eco-physiological processes, the SMPT-SB model was simple and easy to be used. And it can be used as a basic carbon and water coupling model of soil-plant-atmosphere continuum. | REN Chuanyou, YU Guirui, WANG Qiufeng & GUAN Dexin Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China Shenyang Agricultural University, Shenyang 110161, China Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China Graduate School of the Chinese Academy of Sciences, Beijing 100039, China | 2005 | Science China Earth Sciences2005，48，z1： | 5 |
| 11 | The Effects of Groundwater Depth on the Soil Evaporation in Horqin Sandy Land, China显示文摘The interactions between groundwater depth and soil hydrological processes, play an important role in both arid and semi-arid ecosystems. The effect of groundwater depth on soil water variations were neglected or not explicitly treated. In this paper, we combine a simulation experiment and a water flow module of HYDRUS-1D model to study the variation in soil evaporation under different groundwater depth conditions and the relationship between groundwater depth and evaporation efficiency in Horqin Sandy Land, China.The results showed that with an increase in groundwater depth, the evaporation of soil and the recharge of groundwater decrease. In this study, the groundwater recharge did not account for more than 21% of the soil evaporation for the depths of groundwater examined. The soil water content at 60 cm was less affected by the evaporation efficiency when the mean groundwater depth was 61 cm during the experimental period. In addition, the evaporation efficiency(the ratio of actual evaporation to potential evaporation) decreases with the increase in groundwater depth during the experiment. Furthermore, the soil evaporation was not affected by groundwater when the groundwater depth was deeper than 239 cm. | YANG Tingting ALA Musa GUAN Dexin WANG Anzhi | 2021 | Chinese Geographical Science2021，31，4： | 5 |
| 12 | Nasal delivery of broadly neutralizing antibodies protects mice from lethal challenge with SARS-CoV-2 delta and omicron variants显示文摘Multiple new variants of severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)have constantly emerged,as the delta and omicron variants,which have developed resistance to currently gained neutralizing antibodies.This highlights a critical need to discover new therapeutic agents to overcome the variants mutations.Despite the availability of vaccines against coronavirus disease 2019(COVID-19),the use of broadly neutralizing antibodies has been considered as an alternative way for the prevention or treatment of SARS-Co V-2 variants infection.Here,we show that the nasal delivery of two previously characterized broadly neutralizing antibodies(F61 and H121)protected K18-h ACE2 mice against lethal challenge with SARS-Co V-2 variants.The broadly protective efficacy of the F61 or F61/F121 cocktail antibodies was evaluated by lethal challenge with the wild strain(WIV04)and multiple variants,including beta(B.1.351),delta(B.1.617.2),and omicron(B.1.1.529)at 200or 1000 TCID_(50),and the minimum antibody administration doses(5-1.25 mg/kg body weight)were also evaluated with delta and omicron challenge.Fully prophylactic protections were found in all challenged groups with both F61 and F61/H121 combination at the administration dose of 20 mg/kg body weight,and corresponding mice lung viral RNA showed negative,with almost all alveolar septa and cavities remaining normal.Furthermore,low-dose antibody treatment induced significant prophylactic protection against lethal challenge with delta and omicron variants,whereas the F61/H121 combination showed excellent results against omicron infection.Our findings indicated the potential use of broadly neutralizing monoclonal antibodies as prophylactic and therapeutic agent for protection of current emerged SARS-Co V-2 variants infection. | Jia Lu Qiangling Yin Rongjuan Pei Qiu Zhang Yuanyuan Qu Yongbing Pan Lina Sun Ding Gao Cuiqin Liang Jingwen Yang Wei Wu Jiandong Li Zongqiang Cui Zejun Wang Xinguo Li Dexin Li Shiwen Wang Kai Duan Wuxiang Guan Mifang Liang Xiaoming Yang | 2022 | Virologica Sinica2022，37，2： | 4 |
| 13 | UPA2 and ZmRAVL1:Promising targets of genetic improvement of maize plant architecture^∞显示文摘Maize(Zea mays ssp.mays)is a major staple crop,with the highest tonnage among cereal crops worldwide(FAO 2014).Over the past century,maize yields have increased about 8-fold in the US central Corm Belt(from 1,287 kg/ha in the 19305 to 11,084 kg/ha in 2017,http://gffzz7e8ce5e2b4d84f4ehkknxbwubkov96pwx.ffgz.tsg.suse.edu.cn,Duvick 2005b)due to a combination of genetic gain resulting from breeding efforts and im-proved management practices(such as application of synthetic nitrogen fertilizers,weed,and pest control,increased efficiency of harvest equipment,etC.).A major management practice that contributed to the continuous yield increase is continual increases in planting density(from 30,000 plants per hectare or less in the 1930s to 80,000 plants per hectare or higher in the 1980s,Duvick 2005a,2005b).A series of retro-spective studies have suggested that newer hybrids yield more than older hybrids because of improved plant architecture better adapted to high density planting and increased ability to withstand various biotic and abiotic stresses associated with high density planting(ollenaar and Wu 1999;Duvick 2005a,2005b).Although lagging behind the United States,increasing planting density has been a popular practice in other countries as well for increasing grain yield per unit land area in the last few decades(Li et al.2011). | Dexin Kong Baobao Wang Haiyang Wang | 2020 | Journal of Integrative Plant Biology2020，62，4： | 4 |
| 14 | Molecular evolution and genetic diversity analysis of SFTS virus based on next-generation sequencing显示文摘SFTS virus(SFTSV)is a novel bunyavirus,which was discovered as the etiological agent of severe fever with thrombocytopenia syndrome(SFTS)in China in 2009,and was now prevalent in at least 25 provinces in China.SFTS was subsequently identified in South Korea and Japan in 2012.To explore themolecular evolution and genetic characteristics of this newly identified pathogen,we reported 72 whole genome sequences of SFTSV,and built a dataset of SFTSV genome sequences containing 292 L-segment,302 M-segment and 502 S-segment.We clearly divided SFTSV into six genotypes,Genotype A-F.It was found that genotype F was the dominant epidemic genotype of Japan,South Korea,and Zhejiang province of China.The coalescent analysis supported that SFTSV originated in the early 18th century from Zhejiang province,and Genotype F was the most primitive one.Henan,Hubei,and Anhui provinces which are located in Dabie Mountain area weremainly epidemic of Genotype A,which emerged relatively late but distributed widely.A total of 37 recombination events were identified,making SFTSV with a high recombination frequency(L segment 5.1%,Msegment 3.6%,S segment 0.8%)among negative-strand segmented RNA viruses.It was identified that 19 reassortant strains belonged to 12 reassortment forms of SFTSV genome containing 6 newly identified forms.The reassortment virus and recombination in tick were both found for the first time.We also found many of genotype-specific mutation sites,7 of which could be considered as potential molecular marker for genotype classification.This study promoted a more comprehensive understanding of the phylogeny and origin,and the genetic diversity of SFTSV,and it could help the studies of other newly discovered tick-borne bunyavirus as reference data and research ideas. | Aqian Li Lin Liu Wei Wu Yang Liu Xiaoxia Huang Chuan Li Di Liu Jiandong Li Shiwen Wang Dexin Li Mifang Liang | 2021 | Biosafety and Health2021，3，2： | 4 |
| 15 | Light Regulation of Stomatal Development and Patterning: Shifting the Paradigm from Arabidopsis to Grasses显示文摘The stomatal pores of plant leaves control gas exchange with the environment.Stomatal development is prevised regulated by both internal genetic programs and environmental cues.Among various environmental factors,light regulation of stomata formation has been extensively studied in Arabidopsis.In this review,we summarize recent advances in the genetic control of stomata development and its regulation by light.We also present a comparative analysis of the conserved and diverged stomatal regulatory networks between Arabidopsis and cereal grasses.Lastly,we provide our perspectives on manipulation of the stomata density on plant leaves for the purpose of breeding crops that are better adapted to the adverse environment and high-density planting conditions. | Hongbin Wei Dexin Kong Juan Yang Haiyang Wang | 2020 | Plant Communications2020，1，2： | 4 |
| 16 | SNX11 Identified as an Essential Host Factor for SFTS Virus Infection by CRISPR Knockout Screening显示文摘Severe fever with thrombocytopenia syndrome virus(SFTSV)is a highly pathogenic tick-borne bunyavirus that causes lethal infectious disease and severe fever with thrombocytopenia syndrome(SFTS)in humans.The molecular mechanisms and host cellular factors required for SFTSV infection remain uncharacterized.Using a genome-wide CRISPR-based screening strategy,we identified a host cellular protein,sorting nexin 11(SNX11)which is involved in the intracellular endosomal trafficking pathway,as an essential cell factor for SFTSV infection.An SNX11-KO HeLa cell line was established,and SFTSV replication was significantly reduced.The glycoproteins of SFTSV were detected and remained in later endosomal compartments but were not detectable in the endoplasmic reticulum(ER)or Golgi apparatus.pH values in the endosomal compartments of the SNX11-KO cells increased compared with the pH of normal HeLa cells,and lysosomal-associated membrane protein 1(LAMP1)expression was significantly elevated in the SNX11-KO cells.Overall,these results indicated that penetration of SFTSV from the endolysosomes into the cytoplasm of host cells was blocked in the cells lacking SNX11.Our study for the first time provides insight into the important role of the SNX11 as an essential host factor in the intracellular trafficking and penetrating process of SFTSV infection via potential regulation of viral protein sorting,membrane fusion,and other endocytic machinery. | Tiezhu Liu Jiajia Li Yang Liu Yuanyuan Qu Aqian Li Chuan Li Quanfu Zhang Wei Wu Jiandong Li Yan Liu Dexin Li Shiwen Wang Mifang Liang | 2019 | Virologica Sinica2019，34，5： | 3 |
| 17 | High‐sensitivity distributed dynamic strain sensing by combining Rayleigh and Brillouin scattering显示文摘The phase-sensitive optical time-domain reflectometry(φ-OTDR)is a good candidate for distributed dynamic strain sensing,due to its high sensitivity and fast measurement,which has already been widely used in intrusion monitoring,geophysical exploration,etc.For the frequency scanning basedφ-OTDR,the phase change manifests itself as a shift of the intensity distribution.The correlation between the reference and measured spectra is employed for relative strain demodulation,which has imposed the continuous measurement for the absolute strain demodulation.Fortunately,the Brillouin optical time domain analysis(BOTDA)allows for the absolute strain demodulation with only one measurement.In this work,the combination of theφ-OTDR and BOTDA has been proposed and demonstrated by using the same set of frequency-scanning optical pulses,and the frequency-agile technique is also introduced for fast measurements.A 9.9 Hz vibration with a strain range of 500 nεhas been measured under two different absolute strains(296.7μεand 554.8με)by integrating the Rayleigh and Brillouin information.The sub-micro strain vibration is demonstrated by theφ-OTDR signal with a high sensitivity of 6.8 nε,while the absolute strain is measured by the BOTDA signal with an accuracy of 5.4με.The proposed sensor allows for dynamic absolute strain measurements with a high sensitivity,thus opening a door for new possibilities which are yet to be explored. | Benzhang Wang Dexin Ba Qi Chu Liqiang Qiu Dengwang Zhou Yongkang Dong | 2020 | Opto-Electronic Advances2020，3，12： | 3 |
| 18 | Precipitation behaviors and mechanical properties of a solution-treated Mg-Gd-Nd-Zn-Zr alloy during equal-channel angular pressing process显示文摘A magnesium alloy processed by equal-channel angular pressing (ECAP) exhibited excellent microstructure refinement and improved strength and hardness.The comprehensive mechanical properties of magnesium alloys have supported the expansion of their applications in the automotive,aerospace,and biomedical industries.Herein,pre-treatment of a solution-treated Mg-2.9Gd-1.5Nd-0.3Zn-0.3Zr alloy was conducted to investigate the precipitate behavior and microstructure evolution during the ECAP process.β;phase grains quickly precipitated from the solution-treated alloy,which accelerated grain refinement and enhanced the ductility after the ECAP process,as compared to the as-cast alloy reported in our previous study.Moreover,spherical precipitates (~200 nm) and fine phases (~100 nm) precipitated along the stripe-like Zn;Zr;phase,which formed a kabap-like structure dispersing homogeneously in the solution-treated alloy during the ECAP process.Owing to grain refinement,dislocations,sphericalβ;precipitates,and texture evolution,the solution-treated alloy after eight passes of ECAP exhibited good comprehensive mechanical properties,with the ultimate tensile strength,yield strength,and elongation values reaching210.9 MPa,263.9 MPa,and 27.9%,respectively. | Zhenzhen Gui Fen Wang Junyi Zhang Dexin Chen Zhixin Kang | 2022 | Journal of Magnesium and Alloys2022，10，1： | 3 |
| 19 | Antibody Cocktail Exhibits Broad Neutralization Activity Against SARS-CoV-2 and SARS-CoV-2 Variants显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)has precipitated multiple variants resistant to therapeutic antibodies.In this study,12 high-affinity antibodies were generated from convalescent donors in early outbreaks using immune antibody phage display libraries.Of them,two RBD-binding antibodies(F61 and H121)showed high-affinity neutralization against SARS-Co V-2,whereas three S2-target antibodies failed to neutralize SARS-Co V-2.Following structure analysis,F61 identified a linear epitope located in residues G446–S494,which overlapped with angiotensinconverting enzyme 2(ACE2)binding sites,while H121 recognized a conformational epitope located on the side face of RBD,outside from ACE2 binding domain.Hence the cocktail of the two antibodies achieved better performance of neutralization to SARS-Co V-2.Importantly,these two antibodies also showed efficient neutralizing activities to the variants including B.1.1.7 and B.1.351,and reacted with mutations of N501 Y,E484 K,and L452 R,indicated that it may also neutralize the recent India endemic strain B.1.617.The unchanged binding activity of F61 and H121 to RBD with multiple mutations revealed a broad neutralizing activity against variants,which mitigated the risk of viral escape.Our findings revealed the therapeutic basis of cocktail antibodies against constantly emerging SARS-Co V-2 variants and provided promising candidate antibodies to clinical treatment of COVID-19 patients infected with broad SARS-Co V-2 variants. | Yuanyuan Qu Xueyan Zhang Meiyu Wang Lina Sun Yongzhong Jiang Cheng Li Wei Wu Zhen Chen Qiangling Yin Xiaolin Jiang Yang Liu Chuan Li Jiandong Li Tianlei Ying Dexin Li Faxian Zhan Youchun Wang Wuxiang Guan Shiwen Wang Mifang Liang | 2021 | Virologica Sinica2021，36，5： | 3 |
| 20 | Scale up and stability test for oxidative coupling of methane over Na_2WO_4-Mn/SiO_2 catalyst in a 200 ml fixed-bed reactor显示文摘规模在上面的学习在 5wt% Na 2 WO 4-1.9wt% Mn/SiO 2(W-Mn/SiO 2) 催化剂。反应条件的效果详细被调查。结果证明与增加反应温度,煤气阶段的反应被提高,甲烷的重要数量被变换成公司 x ;与 CH 4/O2 5 的臼齿的比率,最高的 C 2( 乙烯和乙烷)25% 的产量被完成;蒸气的存在(同样稀释) 在 C 2 选择和收益上有积极效果。在更低的甲烷下面气体时时, C 2 的空间速度(GHSV ) ,更高的选择和产量作为释放热能的减少的结果被获得。在 100 h 反应时间, C 2 选择 66%61% 并且 C 2 产量 24.2% 没有任何重要损失, 25.4% 被一张单个通行证在催化性能完成。 | Haitao Liu Xiaolai Wang Dexin Yang Runxiong Gao Zhonglai Wang Jian Yang | 2008 | Journal of Natural Gas Chemistry2008，17，1： | 3 |
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