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| 1 | Diagnostic accuracy of endoscopic ultrasound in pancreatic neuroendocrine tumors: A systematic review and meta analysis显示文摘AIM: To detect pancreatic neuroendocrine tumors (PNETs) has been varied. This study is undertaken to evaluate the accuracy of endoscopic ultrasound (EUS) in detecting PNETs.METHODS: Only EUS studies confirmed by surgery or appropriate follow-up were selected. Articles were searched in Medline, Ovid journals, Medline nonindexed citations, and Cochrane Central Register of Controlled Trials and Database of Systematic Reviews. Pooling was conducted by both fixed and random effects model). RESULTS: Initial search identified 2610 reference articles, of these 140 relevant articles were selected and reviewed. Data was extracted from 13 studies (n = 456) which met the inclusion criteria. Pooled sensitivity of EUS in detecting a PNETs was 87.2% (95%CI: 82.2-91.2). EUS had a pooled specificity of 98.0% (95%CI: 94.3-99.6). The positive likelihood ratio of EUS was 11.1 (95%CI: 5.34-22.8) and negative likelihood ratio was 0.17 (95%CI: 0.13-0.24). The diagnostic odds ratio, the odds of having anatomic PNETs in positive as compared to negative EUS studies was 94.7 (95%CI: 37.9-236.1). Begg-Mazumdar bias indicator for publication bias gave a Kendall's tau value of 0.31 (P = 0.16), indication no publication bias. The P for χ2 heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION: EUS has excellent sensitivity and specificity to detect PNETs. EUS should be strongly considered for evaluation of PNETs. | Srinivas R Puli Nikhil Kalva Matthew L Bechtold Smitha R Pamulaparthy Micheal D Cashman Norman C Estes Richard H Pearl Fritz-Henry Volmar Sonu Dillon Michael F Shekleton David Forcione | 2013 | World Journal of Gastroenterology2013，19，23： | 14 |
| 2 | Transcriptional complementarity in breast cancer:application to detection of circulating tumor cells显示文摘 | Houghton R L Dillon D C Molesh D A | 2001 | Mol Diagn2001，6，2： | 1 |
| 3 | A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference显示文摘 | Rubinson D A Dillon C P Kwiatkowski A V | 2003 | Nat Genet2003，33，3： | 1 |
| 4 | Alentivirus-based system to functionally silence genes in primarymammalian cells, stem cells and transgenic mice by RNAinterference 显示文摘 | Rubinson D A Dillon C P Kwiatkowski A J | 2003 | Nat Genet2003，33，3： | 1 |
| 5 | Separation and charac- terization of Nom by high - performance liquid chromatography and on - line three - dimensional excitation emission matrix fluo- rescence detection 显示文摘 | Wu F C Evans R D Dillon P J | 2003 | Environmental Science & Technology2003，37，16： | 1 |
| 6 | Storage ofhydrogen in single - walled carbon nanotubes显示文摘 | A C Dillon K M Jones T A Bekkedahl C H Kiang D S Bethune M J Heben | 1997 | Nature1997，386，： | 1 |
| 7 | A Lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference显示文摘 | Rubinson D A Dillon C P Kwiatkowski A V | 2003 | Nat Genet2003，33，3： | 1 |
| 8 | Serum antibodies to lipophilin B detected in late stage breast cancer patients显示文摘 | Carter D Dillon D C Reynolds L D | 2003 | Clin Cancer Res2003，9，2： | 1 |
| 9 | Zeolite catalysts as solid solvents in fine chemicals synthesis显示文摘 | DEROUANE E G DILLON C J BETHELL D DEROUANE-ABD HAMID S B | 1999 | J Catal1999，187，1： | 1 |
| 10 | A lentivirus-based system to functionally silence genes in primary mammalian cells,stem cells and transgenic mice by RNA interference显示文摘 | Rubinson D A Dillon C P Kwiatkowski A V | 2003 | Nat Genet2003，33，3： | 1 |
| 11 | Variable-density modeling of multiple-cycle aquifer storage and recovery (ASR):importance of anisotropy and layered heterogeneity in brackish aquifers显示文摘 | WARD J D SIMMONS C T DILLON P J | | 0，，06： | 1 |
| 12 | An evaluation of continuous electrodeionization as an in-line process for plating rinsewater recovery显示文摘 | Semmens M J Dillon C D Riley C | 2001 | Environmental Progress2001，20，4： | 1 |
| 13 | Identification of Mycobacterium tuberculosis vaccine candidates using human CD4^+ T-cells expression cloning显示文摘 | Coler R N Dillon D C Skeiky Y A | 2009 | Vaccine2009，27，2： | 1 |
| 14 | A lentivirus-based system to functionally silence genes in primary mammalian cells,stem cells and transgenic mice by RNA interference显示文摘 | Rubinson D A Dillon C P Kwiatkowski A V | 2003 | Nature Genetics2003，33，： | 1 |
| 15 | Separation and characterization of NOM by high-performance liquid chromatography and on-line three-dimensional excitation emission matrix fluorescence detection 显示文摘 | WU F C EVANS R D DILLON P J | 2003 | Environmental Science & Technology2003，37，： | 1 |
| 16 | Acute toxicity ofcadmium,lead,zinc,and their mixtures to stream-resident fishand invertebrates 显示文摘 | Mebane C A Dillon F S Hennessy D P | 2012 | Environmental Toxicology and Chemistry2012，31，6： | 1 |
| 17 | A theoretic- cal analysis of mixed convection in aquifer storage and recovery: How important are density effects?显示文摘 | WARD J D SIMMONS C T DILLON P J | 2007 | Journal of Hydrology2007，343，3： | 1 |
| 18 | A lentivir- us-based system to functionally silence genes in primary mamma- lian cells, stem cells and transgenic mice by RNA interference显示文摘 | Rubinson D A Dillon C P Kwialkowski A V | 2003 | Nat Genet2003，33，： | 1 |
| 19 | Variable- density modeling of multiple-cycle aquifer storage and recovery (ASR): Importance of anisotropy and layered heterogeneity in brackish aquifers显示文摘 | WARD J D SIMMONS C T DILLON P J | 2008 | Journal of Hydrology2008，356，6： | 1 |
| 20 | Fractionation and characterization of fulvic acid immobilized metal ion affinity chromatography显示文摘 | Wu F C Evans R D Dillon P J | 2002 | Anal Chim Acta2002，452，1： | 1 |
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