|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mitotic crossover- an evolutionary rudiment which promotes carcinogenesis of colorectal carcinoma显示文摘Mitotic crossover is a natural mechanism that is a main source of the genetic variability of primitive organisms.In complex organisms such as mammals,it represents an evolutionary rudiment which persisted as one of the numerous DNA repair mechanisms,and results in the production of homozygous allele combinations in all heterozygous genes located on the chromosome arm distal to the crossover.This event is familiar as loss of heterozygosity,which is one of the key mechanisms responsible for the development and progression of almost all cancers.We propose the hypothesis in which mitotic crossover is a principal source of the increased loss of heterozygosity that leads to the initiation and progression of colorectal carcinoma.The hypothesis could be tested by in vitro inhibition of Rad51 protein,orthotopic grafting of human colon cancer tissue into the gut of mice,and treatment with potential inhibitors.After these procedures,the frequency of mitotic crossover would be estimated.The development of selective inhibitors of mitotic crossover could stop further carcinogenesis of colorectal carcinoma,as well as many other neoplastic events.Loss of heterozygosity is an event responsible for carcinogenesis,its reduction by selective inhibitors of mitotic crossover could have a positive effect on cancer chemoprevention,as well as on growth reduction and a cessation in the progression of earlier developed tumors. | Branislav Rovcanin Ivan Ivanovski Olivera Djuric Dimitrije Nikolic Jelena Petrovic Petar Ivanovski | 2014 | World Journal of Gastroenterology2014，20，35： | 2 |
| 2 | Erythrocytic transglutaminase inhibition hemolysis at presentation of celiac disease显示文摘Celiac disease (CD) is a common autoimmune condition.Previously it was considered to be a rare childhood disorder,but is actually considered a relatively common condition,present at any age,which may have multiple complications and manifestations.Hematological disorders of the disease are not uncommon.Among these disorders,the most frequently reported are anemias as a result of iron deficiency,often associated with folate and/or B12 deficiency.Anemias caused by hemolysis are very rarely reported in celiac patients.An 11-year-old girl with a previous uneventful medical history presented with severe hemolytic anemia.Hemolysis was Coombs negative,accompanied by inappropriate low reticulocyte count,despite exaggerated bone marrow hyperplasia of the erythroid precursors which showed normal maturation.Serology for recent infections,including EpsteinBarr virus,parvovirus B19,cytomegalovirus and mycoplasma,were all negative.Levels of serum IgA,IgG and IgM,were all within normal ranges for age.Screeningfor anti-DNA,antinuclear,antineutrophil cytoplasmic,antimicrosomal,antithyroglobulin,and antimitochondrial antibodies and lupus anticoagulants,was negative.She was also negative for human immunodeficiency virus.Conventional therapy with corticosteroids and intravenous immunoglobulin failed.CD was serendipitously discovered upon screening for anti-tissue transglutaminase autoantibodies.The disease was confirmed by biopsy of the small intestine mucosa.The patient recovered with gluten-free diet.A unique case of CD is presented.CD should be serologically screened in each patient with Coombs negative 'immune'hemolytic anemia,particularly if accompanied by 'reticulocytopenia'.A new hemolytic mechanism and very speculative explanation for 'reticulocytopenia'are discussed. | Petar Ivanovski Dimitrije Nikoli Nikola Dimitrijevi Ivan Ivanovski Vojislav Perii | 2010 | World Journal of Gastroenterology2010，16，44： | 1 |
| 3 | Activated liver stellate cells in chronic viral C hepatitis:histopathological and immunohistochemical study 显示文摘 | Nada R T Ivan V B Dimitrije C B | 2009 | J Gastrointestin Liver Dis2009，18，2： | 1 |
| 4 | Good luck and bad luck: how to tell the difference显示文摘 | Karl HalvorTeigen Pia C.Evensen Dimitrij K.Samoilow Karin B.Vatne | 1999 | Eur. J. Soc. Psychol1999，，8： | 1 |
| 5 | Determination of fosethyl aluminium by spectrophotometric method显示文摘 | DIMITRIJE S SVETLANA L MARIJA T | 2001 | Pesticidi2001，16，2： | 1 |
| 6 | On 0-connectedness and 0-clo- sure spaces显示文摘 | Mila M Dimitrije A | 2002 | Topology and its Applications2002，123，1： | 1 |
| 7 | Childhood leukemia genetic bottleneck phenomenon related to TEL-AMLI: the postulation by a mathematical model显示文摘 | Petar Ivanovski Ivan Ivanovski Dimitrije Nikolic Ivana Jovanovic | 2012 | Chinese Medical Journal2012，，6： | 1 |
| 8 | Voc Emission From Oil Refinery and Petrochemical Wastewater Treatment Plant Estimation显示文摘 | Marina A M Dimitrije Z S Jovan M J | 2013 | Hem Ind2013，67，2： | 1 |
| 9 | Seasonal Variation in the Occurrence of Stroke in a Finnish Adult Population: The FINMONICA Stroke Register显示文摘 | Dimitrije Jakovljevic Veikko Salomaa Juhani Sivenius Markku Tamminen Cinzia Sarti Kalervo Salmi Esko Kaarsalo Vihtori Narva Pirjo Immonen-Raiha Jorma Torppa Jaakko Tuomilehto | 1996 | Stroke A Journal of Cerebral Circulation1996，，10： | 1 |
| 10 | Contribution of intermediate filaments to cell stiffness,stiffening,and growth显示文摘 | Ning Wang Dimitrije Stamenovic | 2000 | Am J Physiol Cell Physio2000，1279，： | 1 |
| 11 | Comparison of hysterosonography and hysteroscopy for diagnosing perimenopausal bleeding显示文摘 | D Dimitrij evic M Vasilj evic R Anicic S Brankovic | 2013 | Clinical and experimental obstetrics gynecology2013，40，2： | 1 |
| 12 | 天安·千树显示文摘“千树”场地距上海市中心仅20分钟路程,毗邻苏州河,四通八达,也曾是工业历史的核心地带。如今,它已崛起为当代艺术的繁荣之地。天安中国投资有限公司将此地块开发,希望在融合滨水自然元素的同时,让新与旧和谐共存。规定中,新设计需要保留历史建筑的部分,并需包含住宅、酒店、零售和商业的功能。 | 托马斯·赫斯维克 Lisa Finlay Dani Rossello Diez Jimmy Hung Thomas Impiglia Leo Cheung Claudia Orsetti Dimitrije Miletic Shan Li Vichayuth Meenaphant Vincenzo D’Auria Yuxiang Cao Chris Tsui Nicolas Leuina Osbert So Philipp Nedomlel Philip Hall-Patch Kelin Yue 朱清言(摄) Noah Sheldon(摄) 无 | 2019 | 建筑实践2019，2，11： | 0 |
| 13 | RES:定制材料成形显示文摘该研究策略性地执行了场外和现场施工流程,从而创造出一种能够将浪费最小化的设计和施工方法,无需在现场使用大量脚手架,并能带来成形生产工艺所固有的新的设计潜力。该项目设计了一座采用轻型纤维复合材料的宜居桥梁。桥梁预制件切自工厂的平面纤维材料,然后将其裁剪组合成三维构件,这种方式类似于对大块布料的操作方式。 | Andre Felipe Escudero Dimitrije Miletic Giovanni Parodi Dimitar Pouchnikovl Robert Stuart-Smith | 2015 | 世界建筑导报2015，0，4： | 0 |
| 14 | Target acquisition performance in the presence of JPEG image compression显示文摘This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image.Four new clutter metrics based on image quality assessment are introduced,among which the Haar wavelet-based perceptual similarity index,known as HaarPSI,provides the best target acquisition prediction results.It is shown that the similarity between the target and the background at the boundary between visually lossless and visually lossy compression does not change significantly compared to the case when an uncompressed image is used.In future work,through subjective tests,it is necessary to check whether this presence of compression at the threshold of just noticeable differences will affect the human target acquisition performance.Similarity values are compared with the results of subjective tests of the well-known target Search_2 database,where the degree of agreement between objective and subjective scores,measured through linear correlation,reached a value of 90%. | Boban Bondzulic Nenad Stojanovic Vladimir Lukin Sergey A.Stankevich Dimitrije Bujakovic Sergii Kryvenko | 2024 | Defence Technology(防务技术)2024，33，3： | 0 |
| 15 | 一诺千金——申请加入世贸组织以及加入后的承诺兑现显示文摘困难 毫无疑问许多人都认为如今加入世贸组织,是目前为止最困难、最耗费时日以及在世贸组织现在所有程序中最昂贵的程序。但在一个国家的经济以及在政府管理的许多方面,这些程序都具有非常重要以及长期和短期的影响。或许在加入世贸组织所面临的困难方面,可与其相提并论的唯一程序就是世贸组织中的争端解决程序。 | DIMITRIJ GRCAR 李晓丽 | 1998 | 国际贸易1998，，1： | 0 |
| 16 | 谁让“德国制造”蒙羞?显示文摘依靠集体声誉作为开展营销的公司们永远不应忽视这样一个事实:一个坏苹果,能毁了一桶好苹果。依靠'德国制造'科学严谨、诚信可靠的美誉畅行全球市场的德国企业们,可能因为一家德企的负面消息遭遇打击. | Dimitrije Ruzic | 2019 | 董事会2019，0，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员