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20篇 您的检索式:作者名="Dimitrina"
    题名 作者 年代 出处 被引量
1Desulphurization of damped battery paste by sodium carbonate and sodium hydroxide显示文摘Nedialko K. Lyakov Dimitrina A. Atanasova Venceslav S. Vassilev Georgi A. Haralampiev 2007Journal of Power Sources2007,,2:1
2Influence of different soil moisture on anatomy' of maize leaves and ultra-structure of chloroplast 显示文摘Dimitrina S Elena T Yordanov I 2002Bulg J Plant Physoil2002,28,12:1
3Lyudmil nakovantichlamydial and antisperm antibodies in patients with chlamydial infections显示文摘Dimitrina D Svetoslav K Lyubomir H 2004American Journal of Reproductive Immunology A JRI2004,52,:1
4Mucosal COVID-19 vaccines:Risks,benefits and control of the pandemic显示文摘Based on mucosal immunization to promote both mucosal and systemic immune responses,next-generation coronavirus disease 2019(COVID-19)vaccines would be administered intranasally or orally.The goal of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vaccines is to provide adequate immune protection and avoid severe disease and death.Mucosal vaccine candidates for COVID-19 including vector vaccines,recombinant subunit vaccines and live attenuated vaccines are under development.Furthermore,subunit protein vaccines and virus-vectored vaccines have made substantial progress in preclinical and clinical settings,resulting in SARS-CoV-2 intranasal vaccines based on the previously successfully used nasal vaccines.Additional to their ability to trigger stable,protective immune responses at the sites of pathogenic infection,the development of‘specific’mucosal vaccines targeting coronavirus antigens could be an excellent option for preventing future pandemics.However,their efficacy and safety should be confirmed.Dimitrina Miteva Monika Peshevska-Sekulovska Violeta Snegarova Hristiana Batselova Radostina Alexandrova Tsvetelina Velikova 2022World Journal of Virology2022,11,5:1
5Computer networks as social net- works : collaborative work, telework, and virtual communit), 显示文摘WELLMAN B JANET S DIMITRINA D LAURA G MILE- NA G CAROLINE H 1996Annual Review of Sociology1996,22,:1
6Computer networks association networks: Collabora- tive Work, Telework, and Virtual Community 显示文摘Laura Garton Barry Wellman Janet Salaff Dimitrina Dimitrova Milena Gulia Caroline Haythornthwaite 1996Annu- al Review of Sociology1996,22,:1
7COMPUTER NETWORKS AS SOCIAL NETWORKS: Collaborative Work, Telework, and Virtual Community显示文摘Barry Wellman Janet Salaff Dimitrina Dimitrova Laura Garton Milena Gulia Caroline Haythornthwaite 1996Annual Review of Sociology1996,,:1
8Special theme: project management in e-sci- ence: challenges and opportunities显示文摘SPENCER DIMITRINA ZIMMERMAN ANN ABRAM- SON DAVID 2011Computer Supported Cooperative Work-The Journal of Collaborative Computing2011,20,3:1
9Computer Networks as Social Networks:Collaborative Work,Telework,and Virtual Community显示文摘Wellman Barry Janet Salaff Dimitrina Dimitrova Laura Garton Milean Gulia Carloine Haythornthwaite 1996Annual Review of Sociology1996,22,4:1
10Modelling the joint distribution of competing risk survival times using copula functions显示文摘VLADIMIR K K DIMITRINA S D STEVEN H 2007Math Econ2007,41,:1
11Islet transplantation-immunological challenges and current perspectives显示文摘Pancreatic islet transplantation is a minimally invasive procedure aiming to reverse the effects of insulin deficiency in patients with type 1 diabetes(T1D)by transplanting pancreatic beta cells.Overall,pancreatic islet transplantation has improved to a great extent,and cellular replacement will likely become the mainstay treatment.We review pancreatic islet transplantation as a treatment for T1D and the immunological challenges faced.Published data demonstrated that the time for islet cell transfusion varied between 2 and 10 h.Approximately 54%of the patients gained insulin independence at the end of the first year,while only 20%remained insulin-free at the end of the second year.Eventually,most transplanted patients return to using some form of exogenous insulin within a few years after the transplantation,which imposed the need to improve immunological factors before transplantation.We also discuss the immunosuppressive regimens,apoptotic donor lymphocytes,anti-TIM-1 antibodies,mixed chimerism-based tolerance induction,induction of antigen-specific tolerance utilizing ethylene carbodiimide-fixed splenocytes,pretransplant infusions of donor apoptotic cells,B cell depletion,preconditioning of isolated islets,inducing local immunotolerance,cell encapsulation and immunoisolation,using of biomaterials,immunomodulatory cells,etc.Plamena Kabakchieva Yavor Assyov Stavros Gerasoudis Georgi Vasilev Monika Peshevska-Sekulovska Metodija Sekulovski Snezhina Lazova Dimitrina Georgieva Miteva Milena Gulinac Latchezar Tomov Tsvetelina Velikova 2023World Journal of Transplantation2023,13,4:1
12显示文摘Dimitrina A Lidia A Simona B 2004Solid State Sciences2004,6,11:1
13Applications of time series analysis in epidemiology: Literature review and our experience during COVID-19 pandemic显示文摘Time series analysis is a valuable tool in epidemiology that complements the classical epidemiological models in two different ways:Prediction and forecast.Prediction is related to explaining past and current data based on various internal and external influences that may or may not have a causative role.Forecasting is an exploration of the possible future values based on the predictive ability of the model and hypothesized future values of the external and/or internal influences.The time series analysis approach has the advantage of being easier to use(in the cases of more straightforward and linear models such as Auto-Regressive Integrated Moving Average).Still,it is limited in forecasting time,unlike the classical models such as Susceptible-Exposed-Infectious-Removed.Its applicability in forecasting comes from its better accuracy for short-term prediction.In its basic form,it does not assume much theoretical knowledge of the mechanisms of spreading and mutating pathogens or the reaction of people and regulatory structures(governments,companies,etc.).Instead,it estimates from the data directly.Its predictive ability allows testing hypotheses for different factors that positively or negatively contribute to the pandemic spread;be it school closures,emerging variants,etc.It can be used in mortality or hospital risk estimation from new cases,seroprevalence studies,assessing properties of emerging variants,and estimating excess mortality and its relationship with a pandemic.Latchezar Tomov Lyubomir Chervenkov Dimitrina Georgieva Miteva Hristiana Batselova TsvetelinaVelikova 2023World Journal of Clinical Cases2023,11,29:0
14Effectiveness and safety of COVID-19 vaccines in patients with diabetes as a factor for vaccine hesitancy显示文摘Diabetes mellitus is one of the most common comorbid conditions encountered in patients with severe acute respiratory syndrome coronavirus 2 infection accompanied by significantly increased mortality,prolonged hospital stay,and requirement of invasive mechanical ventilation.This review aims to present the effectiveness and safety profile of available coronavirus disease 2019(COVID-19)vaccines in people with diabetes as a potential cause of hesitancy for vaccination.Data from published research proves a robust immune response following immunization for COVID-19 in diabetic patients with substantial production of virus-neutralizing antibodies;however,the observed immune response was unequivocally weaker than that in individuals without diabetes.This observation was further enhanced by the findings that worse glycemic control was associated with more suppressed antibody production.In contrast,individuals with optimal glycemic control performed similarly to healthy controls.In addition to the need for strict glucose monitoring and adequate diabetes treatment,those findings reinforce the concept of diabetes-induced secondary immune deficiency and necessitate the application of booster doses to diabetic patients with priority.Nevertheless,after vaccination,reported adverse events were not different from those in the general population.No increase in severe adverse events was documented.While single case reports detected transient increases in blood glucose post-vaccination,more extensive trials could not replicate such a relationship.Georgi Vasilev Plamena Kabakchieva Dimitrina Miteva Hristiana Batselova Tsvetelina Velikova 2022World Journal of Diabetes2022,13,9:0
15Hypotheses and facts for genetic factors related to severe COVID-19显示文摘Genome-wide association analysis allows the identification of potential candidate genes involved in the development of severe coronavirus disease 2019(COVID-19).Hence,it seems that genetics matters here,as well.Nevertheless,the virus's nature,including its RNA structure,determines the rate of mutations leading to new viral strains with all epidemiological and clinical consequences.Given these observations,we herein comment on the current hypotheses about the possible role of the genes in association with COVID-19 severity.We discuss some of the major candidate genes that have been identified as potential genetic factors associated with the COVID-19 severity and infection susceptibility:HLA,ABO,ACE2,TLR7,ApoE,TYK2,OAS,DPP9,IFNAR2,CCR2,etc.Further study of genes and genetic variants will be of great benefit for the prevention and assessment of the individual risk and disease severity in different populations.These scientific data will serve as a basis for the development of clinically applicable diagnostic and prognostic tests for patients at high risk of COVID-19.Stanislav Vasilev Kotsev Dimitrina Miteva Stanislava Krayselska Martina Shopova Maria Pishmisheva-Peleva Spaska Angelova Stanilova Tsvetelina Velikova 2021World Journal of Virology2021,10,4:0
16Pandemic control-do's and don'ts from a control theory perspective显示文摘Managing a pandemic is a difficult task.Pandemics are part of the dynamics of nonlinear systems with multiple different interactive features that co-adapt to each other(such as humans,animals,and pathogens).The target of controlling such a nonlinear system is best achieved using the control system theory developed in engineering and applied in systems biology.But is this theory and its principles actually used in controlling the current coronavirus disease-19 pandemic?We review the evidence for applying principles in different aspects of pandemic control related to different goals such as disease eradication,disease containment,and short-or long-term economic loss minimization.Successful policies implement multiple measures in concordance with control theory to achieve a robust response.In contrast,unsuccessful policies have numerous failures in different measures or focus only on a single measure(only testing,vaccines,etc.).Successful approaches rely on predictions instead of reactions to compensate for the costs of time delay,on knowledge-based analysis instead of trial-and-error,to control complex nonlinear systems,and on risk assessment instead of waiting for more evidence.Iran is an example of the effects of delayed response due to waiting for evidence to arrive instead of a proper risk analytical approach.New Zealand,Australia,and China are examples of appropriate application of basic control theoretic principles and focusing on long-term adaptive strategies,updating measures with the evolution of the pandemic.Latchezar Tomov Dimitrina Miteva Metodija Sekulovski Hristiana Batselova Tsvetelina Velikova 2022World Journal of Methodology2022,12,5:0
17COVID-19 in patients with gastrointestinal stromal tumors: Recommendations for management and vaccination显示文摘The coronavirus disease 2019(COVID-19)pandemic profoundly affected the management and treatment of patients with malignancies.Based on the progress reported in the literature,we reviewed the recommendations for treatment and vaccination in patients with gastrointestinal stromal tumor(GIST)during COVID-19.We focus on whether there is a risk and what could be the possible effects of vaccinating patients with GIST/cancer.Since the situation is quickly changing,and the health services have been severely disrupted,the diagnosis,treatment and recommendations for vaccination of these patients against COVID-19 are still not updated.The approval of vaccines in the pandemic gave hope that we would soon be able to return to a more normal life.However,the oncology community needs to adapt and provide the most effective treatment and care models for patients with rare cancer,such as GIST.Collecting data on the impact of vaccination in patients with GIST/cancer also will be beneficial in expanding knowledge about the future planning of treatment strategies and optimizing care in the event of a subsequent pandemic.Violeta Snegarova Dimitrina Miteva Milena Gulinac Monika Peshevska-Sekulovska Hristiana Batselova Tsvetelina Velikova 2022World Journal of Gastrointestinal Pathophysiology2022,13,5:0
18Effectiveness and safety of COVID-19 vaccines in patients with oncological diseases:State-of-the-art显示文摘Although the coronavirus disease 2019(COVID-19)pandemic was declared to be no longer“a public health emergency of international concern”with its wide range of clinical manifestations and late complications,severe acute respiratory syndrome coronavirus 2 infection proved to be a serious threat,especially to the elderly and patients with comorbidities.Patients with oncologic diseases are vulnerable to severe infection and death.Indeed,patients with oncohematological diseases have a higher risk of severe COVID-19 and impaired post-vaccination immunity.Unfortunately,cancer patients are usually excluded from vaccine trials and investigations of post-vaccinal immune responses and the effectiveness of the vaccines.We aimed to elucidate to what extent patients with cancer are at increased risk of developing severe COVID-19 and what is their overall case fatality rate.We also present the current concept and evidence on the effectiveness and safety of COVID-19 vaccines,including boosters,in oncology patients.In conclusion,despite the considerably higher mortality in the cancer patient group than the general population,countries with high vaccination rates have demonstrated trends toward improved survival of cancer patients early and late in the pandemic.Nedelcho Ivanov Boris Krastev Dimitrina Georgieva Miteva Hristiana Batselova Radostina Alexandrova Tsvetelina Velikova 2023World Journal of Clinical Oncology2023,14,9:0
19Long-term effectiveness,outcomes and complications of bariatric surgery显示文摘Dietary imbalance and overeating can lead to an increasingly widespread disease-obesity.Aesthetic considerations aside,obesity is defined as an excess of adipose tissue that can lead to serious health problems and can predispose to a number of pathological changes and clinical diseases,including diabetes;hypertension;atherosclerosis;coronary artery disease and stroke;obstructive sleep apnea;depression;weight-related arthropathies and endometrial and breast cancer.A body weight 20%above ideal for age,gender and height is a severe health risk.Bariatric surgery is a set of surgical methods to treat morbid obesity when other treatments such as diet,increased physical activity,behavioral changes and drugs have failed.The two most common procedures currently used are sleeve gastrectomy and gastric bypass.This procedure has gained popularity recently and is generally considered safe and effective.Although current data show that perioperative mortality is low and better control of comorbidities and short-term complications is achieved,more randomized trials are needed to evaluate the long-term outcomes of bariatric procedures.This review aims to synthesize and summarize the growing evidence on the long-term effectiveness,outcomes and complications of bariatric surgery.Milena Gulinac Dimitrina Georgieva Miteva Monika Peshevska-Sekulovska Ivan P Novakov Svetozar Antovic Milena Peruhova Violeta Snegarova Plamena Kabakchieva Yavor Assyov Georgi Vasilev Metodija Sekulovski Snezhina Lazova Latchezar Tomov Tsvetelina Velikova 2023World Journal of Clinical Cases2023,11,19:0
20Studies on Feeding Habits and Parasitological Status of Red Fox, Golden Jackal, Wild Cat and Stone Marten in Sredna Gora, Bulgaria显示文摘Zvezdelina Kirkova Evgeniy Raychev Dimitrina Georgieva 2011Journal of Life Sciences2011,5,4:0
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