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3篇 您的检索式:作者名="Ding Baomei"
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1Experimental cancer gene therapy by multiple anti-survivin hammerhead ribozymes显示文摘为癌症改进基因治疗的功效,我们设计了指向 survivin mRNA 的暴露的区域的四撞木鲛 ribozyme 侵入人体气管粘膜的病菌(到 R4 的 R1 ) 。除了在里面 vitro 描述,由教材扩展包括了劈开的顺序特性的一颗决心,为细胞增长并且为的试金在 vivo 肿瘤,生长被用来为 ribozyme 效率得分。survivin 表示的产生抑制经由 caspase-3-dependent 小径导致了有丝分裂的大祸和房间死亡。重要地, ribozyme 侵入人体气管粘膜的病菌的管理在一个 hepato 细胞的癌异种皮移植老鼠模型禁止了肿瘤生长。R1, R3 和 R4 ribozymes 的合作表示 synergistically 压制了 survivin 并且当这联合指向 survivin 抄本的所有主要形式,生产了大多数有势力反癌症效果。带在这份报告描述的多重撞木鲛 ribozymes 的侵入人体气管粘膜的病菌对癌症提供了柔韧的基因治疗策略。Qi Fei Hongyu Zhang Lili Fu Xinlan Dai Baomei Gao Min Ni Chao Ge Jinjun Li Xia Ding Yuwen Ke Xuebiao Yao Jingde Zhu 2008Acta Biochimica et Biophysica Sinica2008,40,6:10
2Enhanced biotransformation of 2-phenylethanol with ethanol oxidation in a solid-liquid two-phase system by active dry yeast显示文摘Rong Shaofeng Ding Baomei Zhang Xiaoli 2011Current Microbiology2011,63,5:1
3Programmable Oligonucleotide-Peptide Complexes:Synthesis and Applications显示文摘Nucleic acids form biological blueprint and polypeptides assist life activities,both of which are indispensable to organisms.Recently,oligonucleotide-peptide complexes(OPCs)have shown great potential in biomedicine,material chemistry and other fields due to their considerable stability and programmability.It remains a huge challenge to stably and facilely constructing OPCs that also limits the wide applications.This tutorial review first summarizes the synthesis strategies of OPC conjugation and the corresponding characteristics in detail,then gives examples of the applications of OPCs,and finally presents a prospective overview on challenges and future perspectives of OPCs.This review aims to help researchers understand the current situation and challenges in this field,thereby furthering interests in developing novel OPC synthesis techniques.XU Min ZHOU Baomei DING Yan DU Shanshan SU Mengke LIU Honglin 2022Chemical Research in Chinese Universities2022,38,4:0
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