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| 1 | Photonic devices based on thin-film lithium niobate on insulator显示文摘Lithium niobate on insulator(LNOI)is rising as one of the most promising platforms for integrated photonics due to the high-index-contrast and excellent material properties of lithium niobate,such as wideband transparency from visible to mid-infrared,large electro-optic,piezoelectric,and second-order harmonic coefficients.The fast-developing micro-and nanostructuring techniques on LNOI have enabled various structure,devices,systems,and applications.In this contribution,we review the latest developments in this platform,including ultra-high speed electro-optic modulators,optical frequency combs,opto-electro-mechanical system on chip,second-harmonic generation in periodically poled LN waveguides,and efficient edge coupling for LNOI. | Shuai Yuan Changran Hu An Pan Yuedi Ding Xuanhao Wang Zhicheng Qu Junjie Wei Yuheng Liu Cheng Zeng† Jinsong Xia | 2021 | Journal of Semiconductors2021，42，4： | 2 |
| 2 | Commuting Toeplitz operators on the bidisk显示文摘 | Xuanhao Ding Shunhua Sun Dechao Zheng | 2012 | Journal of Functional Analysis2012，，11： | 1 |
| 3 | The finite rank perturbations of the produce of Hankel and Toeplitz operators 显示文摘 | Ding Xuanhao | 2008 | J Math Anal Appl2008，337，： | 1 |
| 4 | Finite rank commutator of Toeplitz operators or Hankel operators 显示文摘 | Ding Xuanhao Zheng Dechao | 2008 | Houston J Math2008，34，： | 1 |
| 5 | Riesz bases of multivariate translates for Sobolev space显示文摘This paper gives a systematic study of Riesz bases of multivariate translates derived from a fixed compactly supported multivariate function in a Sobolev space.Starting with a multivariate function φ satisfying a very mild condition in Sovolev space Hs(Rd),we provide a necessary and sufficient condition under which {φ(x-n)}n∈Zd is a Riesz basis for span{φ(x-n)}n∈Zd. | ZHANG Guobing DING Xuanhao JIANG Yingchun | 2010 | 商丘师范学院学报2010，26，9： | 0 |
| 6 | 等距同构的Toeplitz算子显示文摘在讨论Lpa(Bn)上的等距及等距同构的Toeplitz算子的基础上,对于1 | Ding Xuanhao(Dept.of Basic Courses) | 1998 | 桂林电子工业学院学报1998，18，2： | 0 |
| 7 | AIFM1 variants associated with auditory neuropathy spectrum disorder cause apoptosis due to impaired apoptosis-inducing factor dimerization显示文摘Auditory neuropathy spectrum disorder(ANSD)represents a variety of sensorineural deafness conditions characterized by abnormal inner hair cells and/or auditory nerve function,but with the preservation of outer hair cell function.ANSD represents up to 15%of individuals with hearing impairments.Through mutation screening,bioinformatic analysis and expression studies,we have previously identified several apoptosis-inducing factor(AIF)mitochondria-associated 1(AIFM1)variants in ANSD families and in some other sporadic cases.Here,to elucidate the pathogenic mechanisms underlying each AIFM1 variant,we generated AIF-null cells using the clustered regularly interspersed short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)system and constructed AIF-wild type(WT)and AIF-mutant(mut)(p.T260A,p.R422W,and p.R451Q)stable transfection cell lines.We then analyzed AIF structure,coenzyme-binding affinity,apoptosis,and other aspects.Results revealed that these variants resulted in impaired dimerization,compromising AIF function.The reduction reaction of AIF variants had proceeded slower than that of AIF-WT.The average levels of AIF dimerization in AIF variant cells were only 34.5%-49.7%of that of AIF-WT cells,resulting in caspase-independent apoptosis.The average percentage of apoptotic cells in the variants was 12.3%-17.9%,which was significantly higher than that(6.9%-7.4%)in controls.However,nicotinamide adenine dinucleotide(NADH)treatment promoted the reduction of apoptosis by rescuing AIF dimerization in AIF variant cells.Our findings show that the impairment of AIF dimerization by AIFM1 variants causes apoptosis contributing to ANSD,and introduce NADH as a potential drug for ANSD treatment.Our results help elucidate the mechanisms of ANSD and may lead to the provision of novel therapies. | YUE QIU HONGYANG WANG HUAYE PAN JING GUAN LEI YAN MINGJIE FAN HUI ZHOU XUANHAO ZHOU KAIWEN WU ZEXIAO JIA QIANQIAN ZHUANG ZHAOYING LEI MENGYAO LI XUE DING AIFU LIN YONG FU DONG ZHANG QIUJU WANG QINGFENG YAN | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，2： | 0 |
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