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| 1 | From Green Super Rice to green agriculture:Reaping the promise of functional genomics research显示文摘Producing sufficient food with finite resources to feed the growing global population while having a smaller impact on the environment has always been a great challenge.Here,we review the concept and practices of Green Super Rice(GSR)that have led to a paradigm shift in goals for crop genetic improvement and models of food production for promoting sustainable agriculture.The momentous achievements and global deliveries of GSR have been fueled by the integration of abundant genetic resources,functional gene discoveries,and innovative breeding techniques with precise gene and whole-genome selection and efficient agronomic management to promote resource-saving,environmentally friendly crop production systems.We also provide perspectives on new horizons in genomic breeding technologies geared toward delivering green and nutritious crop varieties to further enhance the development of green agricul-ture and better nourish the world population. | Sibin Yu Jauhar Ali Shaochuan Zhou Guangjun Ren Huaan Xie Jianlong Xu Xinqiao Yu Fasong Zhou Shaobing Peng Liangyong Ma Dingyang Yuan Zefu Li Dazhou Chen Ruifeng Zheng Zhigang Zhao Chengcai Chu Aiqing You Yu Wei Susong Zhu Qiongyao Gu Guangcun He Shigui Li Guifu Liu Changhua Liu Chaopu Zhang Jinghua Xiao Lijun Luo Zhikang Li Qifa Zhang | 2022 | Molecular Plant2022，15，1： | 6 |
| 2 | Spatial pattern and mechanisms of farmland abandonment in Agricultural and Pastoral Areas of Qingzang Plateau显示文摘With the rapid development of social economy and urban−rural integration,the phenomenon of farmland aban-donment worldwide has proved to be one of the main trends of land use and land cover change(LUCC),and profoundly affected the rural landscape and regional ecological environment.Restricted by the natural environ-ment,economic development and backward agricultural technology,the phenomenon of farmland abandonment is also common in the Qingzang Plateau(QP).Therefore,this paper adopted the spatial autocorrelation method to analyze the spatial pattern of abandonment in the agricultural and pastoral areas of the Qingzang Plateau(APA−QP)in 2017,and the geographically weighted regression(GWR)model to explore the effects of geograph-ical resources,socio-economic development and location conditions on farmland abandonment.This study found that:1)From 2015 to 2017,the abandoned farmland area in the APA−QP was approximately 18.23×10^(4)ha,with an overall abandonment rate of 15.18%.On the whole,it showed the distribution characteristics of“strong in the south and weak in the north,strong in the east and weak in the west”.2)There were positive spatial correlation between both abandoned area and abandonment rate in the APA−QP,showing“concave”and“convex”patterns,respectively,mainly concentrated in the Huang−shui Valley and the Southeast Tibet;while in the western and northern regions,the degree of abandonment was relatively low.3)Farmland abandonment in the APA−QP was mainly driven by the geographical environment changes and farmers’decision−making on farmland utilization.There was significant spatial heterogeneity on farmland abandonment associated with the impact of geographical resources,socio−economics and location conditions.The geographical resource factors had a positive impact on the abandonment,and were strongly constrained by natural geographic conditions such as altitude and slope.The farmland resources in the Qingzang Plateau are limited,but are of strategic significance for the sustainable development of agriculture in the whole Qingzang Plateau.In order to realize the rational distribution of agricul-ture and animal husbandry and the sustainable utilization of farmland resources in the plateau region,land use strategies should be implemented according to regional differences and regional advantages in order to ensure the ecological environment security of Qingzang Plateau. | Yuling Li Tao Zhou Guanghui Jiang Guangyong Li Dingyang Zhou Yu Luo | 2021 | Geography and Sustainability2021，2，3： | 1 |
| 3 | Lyase Activities of Heterologous CpcS and CpcT for Phycocyanin Holo-β-subunit from Arthrospira platensis in Escherichia coli显示文摘Arthrospira platensis is an economically important cyanobacterium; and it has been used widely in food and pharmaceutical industries. The phycocyanin(PC) from A. platensis is extremely valuable in medicine and molecular biology due to its antioxidation and anti-tumoring activity and applicability as fluorescence protein tag. In present study, two recombinant plasmids, one contained the phycocyanobilin(PCB)-producing genes(hox1 and pcyA) while the other contained the phycobiliprotein gene(cpcB) and the lyase gene(either cpcS/U or cpcT), were constructed and synchronically transferred into E. coli in order to test the the activities of relevant lyases for catalysing PCB addition to CpcB during synthesizing fluorescent PC holo-β-subunit(β-PC) of A. platensis. As was evidenced by the fluorescence emitted at a peak specific for PC, CpcB was successfully synthesized in E. coli, to which co-expressed PCBs attached though at a relatively low efficiency. The results showed that the attachment of PCBs to CpcB were carried out mainly by co-expressed CpcS/U but CpcB also showed some autocatalytic activity. Currently, no CpcT activity was detected in this E. coli expression system. Further studies will be conducted to improve the efficiency of fluorescent PC synthesis in E. coli. | YI Junjie XU Di ZANG Xiaonan YUAN Dingyang ZHAO Bingran TANG Li TAN Yanning ZHANG Xuecheng | 2014 | Journal of Ocean University of China2014，13，3： | 1 |
| 4 | Engineered human spinal cord-like tissues with dorsal and ventral neuronal progenitors for spinal cord injury repair in rats and monkeys显示文摘Transplanting human neural progenitor cells is a promising method of replenishing the lost neurons after spinal cord injury (SCI), but differentiating neural progenitor cells into the diverse types of mature functional spinal cord neurons in vivo is challenging. In this study, engineered human embryonic spinal cord-like tissues with dorsal and ventral neuronal characters (DV-SC) were generated by inducing human neural progenitor cells (hscNPCs) to differentiate into various types of dorsal and ventral neuronal cells on collagen scaffold in vitro. Transplantation of DV-SC into complete SCI models in rats and monkeys showed better therapeutic effects than undifferentiated hscNPCs, including pronounced cell survival and maturation. DV-SC formed a targeted connection with the host’s ascending and descending axons, partially restored interrupted neural circuits, and improved motor evoked potentials and the hindlimb function of animals with SCI. This suggests that the transplantation of pre-differentiated hscNPCs with spinal cord dorsal and ventral neuronal characteristics could be a promising strategy for SCI repair. | Bai Xu Dingyang Liu Weiyuan Liu Ge Long Wenbin Liu Yayu Wu Xinghui He Yeyu Shen Peipei Jiang Man Yin Yongheng Fan He Shen Liyang Shi Qi Zhang Weiwei Xue Chen Jin Zhenni Chen Bing Chen Jiayin Li Yali Hu Xing Li Zhifeng Xiao Yannan Zhao Jianwu Dai | 2023 | Bioactive Materials2023，，9： | 0 |
| 5 | Safety and Efficacy of Biodegradable Patent Foramen Ovale Occluder in Patients with Migraine:A Clinical Trial显示文摘Background:Transcatheter closure of patent foramen ovale(PFO)has been widely accepted as a highly effective way to treat high-risk PFO-related diseases.However,traditional non-degradable occluders made of metal alloys will permanently exist in the body,resulting in thrombosis,valve damage,hemolysis,arrhythmia,or other complications.The biodegradable PFO occluder developed by Shanghai Mallow Medical Instrument Co.,Ltd.,China can be fully absorbed and degrade into nontoxic ingredients,reducing postoperative complications.Objectives:To study the safety and efficacy of biodegradable PFO occluders in treating PFO.Methods:This single-center clinical trial collected 30 patients treated with a biodegradable PFO occluder.The follow-up period lasted 12 months to analyze the echocardiographic characteristics and headache relief through HIT-6 scores.Results:The immediate success rate was 100%,with no intraoperative severe occlusion-related complications.The contrast transcranial Doppler(cTCD)at 12 months showed that all patients’right-to-left shunts(RLS)were grade I or 0 with no serious postoperative complications,indicating the overall success rate was 100%.The biodegradable PFO occluder mostly degraded six months after the occlusion.Conclusion:PFO closure with a Mallow biodegradable occluder is safe and effective and has no severe complications. | Xingbang Li Xuan Zheng Bowen Jin Yunyan Li Yongyu Shao Xiaoxian Deng Dingyang Li Shanshan Li Hongmei Zhou Jie Zhang Xianya Zhang Qunshan Shen Gangcheng Zhang | 2023 | Congenital Heart Disease2023，18，3： | 0 |
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