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| 1 | 大高良姜的药理学及植物化学研究综述(英文)显示文摘传统医学使用大量具有医用及药用价值的植物治疗疾病,因此是生物活性物质的一个宝库。姜科植物大高良姜通常被用作调经剂、催欲剂、堕胎药、驱风剂、退热剂和抗炎药等,可用于治疗支气管炎、心脏疾病、慢性肠炎、肾结石、糖尿病、风湿病及肾脏疾病。大高良姜含有精油、鞣酸、苯酚、苷类、单萜及糖类等。过去几年,有报道大高良姜各部位提取物中还含有没食子酸、生姜异黄酮、β-谷甾醇、高良姜素、良姜素、花姜酮、山萘素等。本文总结了近年来有关大高良姜的研究中新的植物化学成分及药理学的研究内容。 | Dhirender Kaushik Jyoti Yadav Pawan Kaushik Disha Sacher Ruby Rani | 2011 | 中西医结合学报2011，9，10： | 10 |
| 2 | Performance analysis of machine learning models for intrusion detection system using Gini Impurity-based Weighted Random Forest (GIWRF) feature selection technique显示文摘To protect the network, resources, and sensitive data, the intrusion detection system (IDS) has become a fundamental component of organizations that prevents cybercriminal activities. Several approaches have been introduced and implemented to thwart malicious activities so far. Due to the effectiveness of machine learning (ML) methods, the proposed approach applied several ML models for the intrusion detection system. In order to evaluate the performance of models, UNSW-NB 15 and Network TON_IoT datasets were used for offline analysis. Both datasets are comparatively newer than the NSL-KDD dataset to represent modern-day attacks. However, the performance analysis was carried out by training and testing the Decision Tree (DT), Gradient Boosting Tree (GBT), Multilayer Perceptron (MLP), AdaBoost, Long-Short Term Memory (LSTM), and Gated Recurrent Unit (GRU) for the binary classification task. As the performance of IDS deteriorates with a high dimensional feature vector, an optimum set of features was selected through a Gini Impurity-based Weighted Random Forest (GIWRF) model as the embedded feature selection technique. This technique employed Gini impurity as the splitting criterion of trees and adjusted the weights for two different classes of the imbalanced data to make the learning algorithm understand the class distribution. Based upon the importance score, 20 features were selected from UNSW-NB 15 and 10 features from the Network TON_IoT dataset. The experimental result revealed that DT performed well with the feature selection technique than other trained models of this experiment. Moreover, the proposed GIWRF-DT outperformed other existing methods surveyed in the literature in terms of the F1 score. | Raisa Abedin Disha Sajjad Waheed | 2022 | Cybersecurity2022，5，2： | 2 |
| 3 | Turn-on fluorescence probe for selective detection of Hg(Ⅱ)by calixpyrrole hydrazide reduced silver nanoparticle: Application to real water sample显示文摘A simple and quick method for the synthesis of water dispersible stable silver nanoparticles has been developed. Calix[4]pyrrole octahydrazide(CPOH), has been successfully used as a reducing as well as stabilizing agent for the synthesis of silver nanoparticles. CPOH-AgNps have been duly characterized by SPR, PSA, TEM and EDX-ray. The ability of CPOH-AgNps as selective and sensitive sensor for various ions(Pb(Ⅱ), Cd(Ⅱ), Mn(Ⅱ), Fe(Ⅲ), Ni(Ⅱ), Zn(Ⅱ), Hg(Ⅱ), Co(Ⅱ), Cu(Ⅱ)) by colorimetry and spectrofluorimetry has been explored. CPOH-AgNps were found to be selective only for Hg(Ⅱ) ions. Nanomolar concentration of Hg(Ⅱ) ions can also be determined by spectrofluorimetry by increase in fluorescence intensity. Linear range of detection of Hg(Ⅱ) ions in water was found to be from 1 nmol/L to 1 μmol/L. The method has been successfully applied for determination of Hg(Ⅱ) ions in ground water and industrial effluent waste water samples. | Keyur D. Bhatt Disha J. Vyas Bharat A. Makwana Savan M. Darjee Vinod K. Jain Hemangini Shah | 2016 | Chinese Chemical Letters2016，27，5： | 2 |
| 4 | Solid phase extraction, preconcetraction and sequential separation of U ( VI ), Th ( IV ),La(III) and Ce(III) by Octa-O-met hoxy resorcin arene based Amberlite XAD -4 chelating resin 显示文摘 | Keyur D Bhatt Disha J Vyas Hrishikesh S Gupte | 2014 | World Journal of Analy-tical Chemistry2014，2，： | 1 |
| 5 | Developmental Expression of Pluripotency Determining Factors in Caprine Embryos: Novel Pattern of NANOG Protein Localization in the Nueleolus 显示文摘 | Shuyang He Disha Pant Andrew Schiffmacher | 2006 | Molecular Reproduction and Development2006，73，： | 1 |
| 6 | Potential interaction between the GARS-AIRS-GART Gene and CP2/LBP-1c/LSF transcription factor in down syndrome-related alzheimer disease显示文摘 | Disha B Krishnadas N | 2007 | Cell Mol Neurobiol2007，27，： | 1 |
| 7 | Comparison of various methodsfor the detection of extended spectrum beta-lactamase in Klebsiellapneumoniae isolated from neonatal intensive care unit Ahmedabad显示文摘 | Dhara M Disha P Sachin P | 2012 | NJMR2012，2，3： | 1 |
| 8 | Risk of late aortic events after an isolated aortic valve replacement for bicuspid aortic valve stenosis with concomitant ascending aortic dilation ? 显示文摘 | Evaldas Girdauskas Kushtrim Disha Heinrich H. Raisin Maria-Anna Secknus Michael A. Borger Thomas Kuntze | 2012 | European Journal of Cardio-Thoracic Surgery2012，，5： | 1 |
| 9 | An Analysis of Security Challenges in Cloud Computing显示文摘 | Parekh Ms Disha H R Sridaran | 2013 | International Journal of Ad- vanced Computer Science and Applications2013，4，1： | 1 |
| 10 | Long-term prognosis of ascending aortic aneurysm after aortic valve replacement for bicuspid versus tricuspid aortic valve stenosis显示文摘 | Girdauskas E Disha K Borger MA | 2014 | J Thorac Cardiovasc Surg2014，147，： | 1 |
| 11 | Design and Synthesis of a Series of Novel Macrocycle Janus Kinase 2 Inhibitors显示文摘Summary of main observation and conclusion Macrocycle has attracted the attention of many researchers in the field of medicinal chemistry due to its unique advantages and good prospects,but the difficulties in drug design and synthesis of macrocycle limit its applications.In this study,a series of macrocyclic derivatives designed from anaplastic lymphoma kinase(ALK)inhibitor lorlatinib were synthesized as Janus kinase 2(JAK2)selective inhibitors.Among them,17f had the best inhibitory activity(IC50=0.177μmol·L^-1)and selectivity for JAK2 over JAK1 and JAK3,which indicated that design of the macrocyclic derivatives might be a feasible strategy for the discovery of novel selective JAK2 inhihitors. | Yanling Wang Huan Ge Disha Wang Huan He Lu Li Yanyan Diao Zihao Shen Lili Zhu Shiliang Li Zhenjiang Zhao Honglin Li | 2019 | Chinese Journal of Chemistry2019，37，12： | 1 |
| 12 | Emergence delirium inchildren: a rando -mized trial to compare total intravenous anesthesiawith propofol and remifentanil to inhalational sevoflurane anesthesia显示文摘 | John R C Dorothy M Disha M | 2013 | Paediatric anaesthesia2013，23，4： | 1 |
| 13 | Increased risk of late aortic events alter isolated aortic valve replacement in patients with bicuspid aortic valve insufficiency versus stenosis显示文摘 | Girdauskas E Disha K Secknus M | 2013 | The Journal of cardiovas- cular surgery2013，54，5： | 1 |
| 14 | Differently synthesized gold nanoparticles respond differently to functionalization with L-amino acids显示文摘The potential utility of gold nanoparticles(AuNPs)synthesized via different methods for biomedical applications vary greatly due to inherent differences in their surface properties.In the present study,we investigated the functionalization of AuNPs synthesized by chemical reduction,plant extract,and bacteria-mediated methods with 22 L-amino acids.Nanoparticles produced by bacteria-mediated(B_AuNPs)and plant-mediated(P_AuNPs)methods showed good potential,as they were able to be functionalized with six(histidine,lysine,methionine,phenylalanine,tryptophan,and tyrosine)and four(cystine,tryptophan,tyrosine,and valine)amino acids,respectively.In contrast,AuNPs produced by chemical reduction(C_AuNPs)were not found to be suitable for functionalization.Optimal functionalization conditions were found to be amino acid concentration of 20-25 mM and neutral pH(7)for P_AuNPs,whereas B_AuNPs tolerated more variable conditions.The electrophoretic mobility of P_AuNPs after functionalization indicated that these nanoparticles were less sensitive than B_AuNPs to the deviations from optimal conditions.A significant change in mobility was observed when B_AuNPs were functionalized with either methionine or tryptophan.Overall,the results of this study suggest that the suitability of the three differently synthesized AuNPs with amino acids is in the following order:B_AuNPs>P_AuNPs>C_AuNPs. | Darshana V.Havaldar Reshma V.Patil Disha N.Moholkar Priyanka S.Magdum Akash P.Vadrale Kiran D.Pawar | 2020 | Particuology2020，18，5： | 1 |
| 15 | Comparative accuracy of mammography and ultrasound in women with breast symptoms according to age and breast density显示文摘 | Devolli Disha E Manxhuka-Kerliu S Ymeri H | 2009 | Basic Med Sci2009，9，2： | 1 |
| 16 | Different anesthesia regimes modulate the functional connectivity outcome in mice显示文摘 | Elisabeth Jonckers Rafael Delgado y Palacios Disha Shah Caroline Guglielmetti Marleen Verhoye Annemie Linden | 2014 | Magn. Reson. Med2014，，4： | 1 |
| 17 | Emergence delirium in children: a randomized trial to compare total intravenous anesthesia with propofol and remifentanil to inhalational sevoflurane anesthesia显示文摘 | John R. Chandler Dorothy Myers Disha Mehta Emma Whyte Michelle K. Groberman Carolyne J. Montgomery J. Mark Ansermino | 2013 | Paediatr Anaesth2013，，4： | 1 |
| 18 | Persistent left superior vena cava in association with sinus venosus defect type of atrial septal defect and partial pulmonary venous return on 64-MDCT显示文摘 | DISHA B PRAKASHINI K SHETTY RK | 2014 | BMJ Case Rep2014，20，13： | 1 |
| 19 | COVAX-19 ■Vaccine:Completely blocks virus transmission to non-immune individuals显示文摘Various vaccine platforms are geared against COVID-19 vaccine development to produce immunogens in cells.To design a recombinant protein-based COVID-19 vaccine,Vaxine pty Ltd used computer models of the spike protein and its human receptor,ACE2,to identify how the virus infects human cells.Based on this,the COVAX-19 ■vaccine is synthesized.It does reduce not only COVID-19 disease but also blocks virus shedding and transmission.Researchers are optimistic that this vaccine candidate could be clinically available soon with sufficient vaccine efficacy with a considerable amount of reduction in vaccination-related side effects. | Vivek P.Chavda Lalitkumar K.Vora Disha R.Vihol | 2021 | Clinical Complementary Medicine and Pharmacology2021，1，1： | 0 |
| 20 | Different Methods on Predicting Deflections on Beams Reinforced with CFRP Bars显示文摘The use of fiber reinforced polymer(FRP)bars to substitute the steel bars in internal reinforcement is now an alternative in some structures subjected by corrosion.The strength,stiffness and bond characteristics of FRP bars are tested to understand their flexural behaviour.In this study is investigated the way of failure of beams reinforced internally with carbon FRP(CFRP)bars and their mechanical properties.Two sets of concrete beams reinforced with different diameters of CFRP bars are designed and tested under four-point loading methods.In general,beams reinforced with FRP bars show more deflections and greater values of crack width than beams reinforced with conventional steel,which is due to their low modulus of elasticity and general stiffness.In this paper is presented the calculation and comparison of deflection using different methods,such as ACI 440,CAN/CSA,Eurocode and experimental loading tests.The evaluation is done comparing the results of every method.This study is effective when we use beams with one layer of reinforcement. | Drilona Disha Hektor Cullufi | 2021 | Journal of Civil Engineering and Architecture2021，15，4： | 0 |
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