|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Fecal microbiota transplantation as novel therapy in gastroenterology:A systematic review显示文摘AIM:To study the clinical efficacy and safety of Fecal microbiota transplantation(FMT).We systematically reviewed FMT used as clinical therapy.METHODS:We searched MEDLINE,EMBASE,the Cochrane Library and Conference proceedings from inception to July,2013.Treatment effect of FMT was calculated as the percentage of patients who achieved clinical improvement per patient category,on an intention-to-treat basis.RESULTS:We included 45 studies;34 on Clostridium difficile-infection(CDI),7 on inflammatory bowel disease,1 on metabolic syndrome,1 on constipation,1 on pouchitis and 1 on irritable bowel syndrome(IBS).In CDI 90% resolution of diarrhea in 33 case series(n = 867) was reported,and 94% resolution of diarrhea after repeated FMT in a randomized controlled trial(RCT)(n = 16).In ulcerative colitis(UC) remission rates of 0% to 68% were found(n = 106).In Crohn's disease(CD)(n = 6),no benefit was observed.In IBS,70% improvement of symptoms was found(n = 13).100% Reversal of symptoms was observed in constipation(n = 3).In pouchitis,none of the patients(n = 8) achieved remission.One RCT showed significant improvement of insulin sensitivity in metabolic syndrome(n = 10).Serious adverse events were rare.CONCLUSION:FMT is highly effective in CDI,and holds promise in UC.As for CD,chronic constipation,pouchitis and IBS data are too limited to draw conclusions.FMT increases insulin sensitivity in metabolic syndrome. | Noortje G Rossen John K Mac Donald Elisabeth M de Vries Geert R D'Haens Willem M de Vos Erwin G Zoetendal Cyriel Y Ponsioen | 2015 | World Journal of Gastroenterology2015，21，17： | 41 |
| 2 | Gastroenterology service in a teaching hospital in rural New Zealand, 1991-2003显示文摘AIM: To retrospectively collect inpatient and outpatient data and to assess the use of endoscopic procedures during the years 1991, 1997 and 2003 to analyse for trends. METHODS: This retrospective survey was conducted in a University-associated Gastroenterology Unit offering secondary and tertiary health care services for a population of approximately 182 000 people in Southern New Zealand. Data collected included patient contacts (inand outpatients), gastroscopic and colonoscopic investigations. RESULTS: We observed a significant increase in the absolute numbers of patient contacts over the years (1991: 2308 vs 1997: 2022 vs 2003: 2783, P < 0.0001) with inflammatory bowel disease, other diseases of the colon, anus and rectum and iron studies related disorders decreasing significantly but liver disease and constipation increasing linearly over time. The use of endoscopy services remained relatively stable but colonoscopic investigations for a positive family history of colorectal cancer increased significantly while more gastroscopies were performed for unexplained anaemia. CONCLUSION: The whole spectrum of gastroenterology contacts was studied. A substantial proportion of colonoscopies and outpatient consultations were undertaken to screen for colorectal cancer. This proportion is likely to grow further. Our fi ndings have implications for the recruitment and training of the next generation of gastroenterologists. | Michael Schultz Andrew Davidson Sarah Donald Bogna Targonska Angus Turnbull Susan Weggery Vicki Livingstone John D Dockerty | 2009 | World Journal of Gastroenterology2009，15，5： | 3 |
| 3 | T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression显示文摘 | Elena Klyushnenkova Joseph D Mosca Valentina Zernetkina Manas K Majumdar Kirstin J Beggs Donald W Simonetti Robert J Deans Kevin R McIntosh | 2005 | Journal of Biomedical Science2005，，1： | 2 |
| 4 | A multicenter, double-blind, one-year study comparing safety and efficacy of atorvastatin versus simvastatin in patients witb hypercholesterolemia显示文摘 | Anthony Dart George Jerums Geoffrey Nicholson Michael d’Emden Ian Hamilton-Craig George Tallis James Best Malcolm West David Sullivan Peter Braes Donald Black | 1997 | The American Journal of Cardiology1997，，： | 2 |
| 5 | Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial显示文摘 | A David Mendelow Barbara A Gregson Helen M Fernandes Gordon D Murray Graham M Teasdale D Terence Hope Abbas Karimi M Donald M Shaw David H Barer | 2005 | 2005 (9457)2005，，9457： | 2 |
| 6 | Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘 | Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A | 2012 | EN2012，，10： | 2 |
| 7 | Exploratory bioavailability and pharmacokinetic studies of sulphadime-thoxine and ormetoprim in the penaeid shrimp, Penaeus vannamei 显示文摘 | Eric D P Donald V L Nicholas M | 1995 | Aquaculture1995，130，： | 1 |
| 8 | Effect of changes in syringe driver height on flow~ a small quanti- tative study显示文摘 | Donald A I Chinthamuneedi M P Spearritt D | 2007 | Crit Care Resusc2007，9，2： | 1 |
| 9 | Rotation and fertilization effects on corn and soybean yields and soybean cyst nematode populations in a no-tillage system显示文摘 | Donald D H | 1998 | Agronomy Journal1998，90，4： | 1 |
| 10 | Cancer-specific loss of hu- man beta-defensin-1 in human renal and prostatic carcinomas显示文摘 | Donald C D Sun S Q Lim S D | 2003 | Lab Invest2003，83，： | 1 |
| 11 | Mechanisms of adverse effects of anti-VEGF therapy for cancer 显示文摘 | Kamba T Mc Donald D M | 2007 | Br J Cancer2007，96，12： | 1 |
| 12 | Unique application of car-bon-carboncomposite materials(part two)显示文摘 | Donald L S Kenneth E D | 1999 | Sample Journal1999，35，4： | 1 |
| 13 | Autologous porcine heart cell transplantation improved heart function after a myocardial infarction显示文摘 | Ren-Ke Li Richard D Weisel Donald A B Mickle | 2000 | The Journal of Thoracic and Cardiovascular Surgery2000，119，1： | 1 |
| 14 | Magnetorheological finishing in commercial precision optics manufacturing显示文摘 | Golini D Donald Kordonski W I | 1999 | SPIE1999，3782，： | 1 |
| 15 | Evaluation of a school-based intervention for HIV/AIDS prevention among Belizean adolescents显示文摘 | Janni Kinsler Carl D Sneed Donald E Monsky | 2004 | Health Education Research2004，19，6： | 1 |
| 16 | Real Estate Versus Financial Wealth in Consumption显示文摘 | Benjamin John D Chinloy P Donald Jud G | | 0，，03： | 1 |
| 17 | Hydraulic Performance of a Steep Single Layer Riprap Drainage Channel显示文摘 | ROBERT N E DONALD D G | 2008 | Journal of Hydraulic Engineering2008，134，11： | 1 |
| 18 | Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial显示文摘 | A David Mendelow Barbara A Gregson Helen M Fernandes Gordon D Murray Graham M Teasdale D Terence Hope Abbas Karimi M Donald M Shaw David H Barer | 2005 | The Lancet2005，，9457： | 1 |
| 19 | Labour analgesia and ce- sarean delivery an individual patient metaanalysis of mulliparouswomen 显示文摘 | Shamla S K Donald D D Wiley J R | 2004 | Amesthesiology2004，100，6： | 1 |
| 20 | Evaluation of the psyehometrie properties of the phlebitisang infiltration scales for the assessment of complications of peripheral vaseular access deviees显示文摘 | Groll D Davies B Mae Donald J | 2010 | J Infus Nurs2010，33，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员