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| 1 | Tribological Properties of Magnesium Ion-exchanged α-Zirconium Phosphate as a Solid Lubricant Additive in Lithium Grease显示文摘Magnesium ion-exchanged a-zirconium phosphates(Mg-α-ZrP) with particle sizes of 600 and 80 nm were prepared through the sealed ion-exchange and one-step hydrothermal synthesis methods, respectively. It was found that larger particles of Mg-α-ZrP had a higher load-carrying capacity than that of smaller particles, whereas smaller Mg-α-ZrP particles had better anti-wear properties than that of larger Mg-α-ZrP particles under mild loads. The correlation between the particle size of the sample and the surface roughness of the friction pair thus seems to be a key factor influencing the performance. | 张效胜 徐红 DONG Jinxiang | 2019 | Journal of Wuhan University of Technology(Materials Science)2019，34，1： | 6 |
| 2 | TXNDC5 synergizes with HSC70 to exacerbate the inflammatory phenotype of synovial fibroblasts in rheumatoid arthritis through NF-κB signaling显示文摘The upregulated expression of thioredoxin domain-containing protein 5(TXNDC5)is associated with rheumatoid arthritis in patients and model mice.However,the underlying mechanism by which TXNDC5 influences the pathological activation of rheumatoid arthritis synovial fibroblasts(RASFs)remains unknown.In this study,we show that TXNDC5 expression in RASFs and their cytokine production are significantly upregulated in response to LPS,TNF-αand IL-6,but suppressed by transfection with TXNDC5-siRNA.TXNDC5 is further validated as the direct target of NF-κB signaling.Mechanistically,TXNDC5 directly interacts with heat shock cognate 70 protein(HSC70)to sequester it in the cytoplasm,and HSC70 silencing exerts the same effects as TXNDC5 on the biological activity of RASFs(for example,decreased cell viability,invasion and cytokine production).Furthermore,HSC70 activates NF-κB signaling by destabilizing IκBβprotein in the absence of LPS or facilitating its nuclear translocation in the presence of LPS.Importantly,TXNDC5 can also regulate the activity of NF-κB signaling in a HSC70-IκBβ-dependent manner.Taken together,by linking HSC70 and NF-κB signaling,TXNDC5 plays a pro-inflammatory role in RASFs,highlighting a potential approach to treat RA by blocking the TXNDC5/HSC70 interaction. | Lin Wang Hongyan Dong Guanhua Song Rui Zhang Jihong Pan Jinxiang Han | 2018 | Cellular & Molecular Immunology2018，15，7： | 5 |
| 3 | Phase 1 studies comparing safety, tolerability, pharmacokinetics and pharmacodynamics of HLX01(a rituximab biosimilar) to reference rituximab in Chinese patients with CD20-positive B-cell lymphoma显示文摘Objective: This study aimed to compare the pharmacokinetic, pharmacodynamic and safety profiles of HLX01(a rituximab biosimilar) and reference rituximab sourced from China(Mab Thera?;rituximab-CN).Methods: Here we report the results of two phase 1 studies. In the phase 1 a, open-label, dose-escalation study(NCT03218072, CTR20140400), eligible patients received 250, 375 and 500 mg/m^(2) HLX01 sequentially at 7-day intervals, after confirming no dose-limiting toxicity(DLT). In the phase 1 b, double-blind study(NCT02584920,CTR20140764), eligible patients were given a single dose of 375 mg/m^(2) HLX01 or rituximab-CN. The primary endpoints included safety and tolerability parameters for the phase 1 a and the area under the plasma concentrationtime curve from time zero to day 91(AUC0-91 d) for the phase 1 b study. Equivalence was concluded if 90%confidence interval(90% CI) for the geometric least squares mean ratio(GLSMR) fell in the pre-specified equivalence criteria(80%-125%).Results: Between June 20, 2014 and January 5, 2015, 12 patients were enrolled in the phase 1 a study. The pharmacokinetics of HLX01 showed dose proportionality and accumulation to steady state. HLX01 was well tolerated, with no serious adverse events(AEs), discontinuations or DLTs. Between November 8, 2014 and August13, 2015, 87 eligible patients were enrolled in the phase 1 b study, including 43 who received HLX01 and 44 who were treated with rituximab-CN. The equivalence endpoint was met with GLSMR for AUC0-91 d being 89.6%(90% CI: 80.4%-99.8%). AEs, anti-drug antibodies, and CD19+ and CD20+ B lymphocyte counts were similar between the HLX01 and rituximab-CN treatment groups.Conclusions: Treatment with HLX01 was safe and well tolerated in Chinese patients with B-cell lymphoma.HLX01 and rituximab-CN have similar pharmacokinetic, pharmacodynamic and safety profiles. | Yuankai Shi Qingyuan Zhang Xiaohong Han Yan Qin Xiaoyan Ke Hang Su Li Liu Jinxiang Fu Jie Jin Jifeng Feng Xiaonan Hong Xiaohong Zhang Depei Wu Bin Jiang Xiaodong Dong | 2021 | Chinese Journal of Cancer Research2021，33，3： | 5 |
| 4 | Boosted cascade of scattered rectangle features for object detection显示文摘This paper presents a variant of Haar-like feature used in Viola and Jones detection framework,called scattered rectangle feature,based on the common-component analysis of local region feature. Three common components,feature filter,feature structure and feature form,are extracted without concern-ing the details of the studied region features,which cast a new light on region feature design for spe-cific applications and requirements: modifying some component(s) of a feature for an improved one or combining different components of existing features for a new favorable one. Scattered rectangle feature follows the former way,extending the feature structure component of Haar-like feature out of the restriction of the geometry adjacency rule,which results in a richer representation that explores much more orientations other than horizontal,vertical and diagonal,as well as misaligned,detached and non-rectangle shape information that is unreachable to Haar-like feature. The training result of the two face detectors in the experiments illustrates the benefits of scattered rectangle feature empirically; the comparison of the ROC curves under a rigid and objective detection criterion on MIT+CMU upright face test set shows that the cascade based on scattered rectangle features outperforms that based on Haar-like features. | ZHANG WeiZe TONG RuoFeng DONG JinXiang | 2009 | Science in China(Series F)2009，52，2： | 2 |
| 5 | Alkylation of naphthalene with n-butene catalyzed by liquid coordination complexes and its lubricating properties显示文摘With the development of coal chemical industry,large amounts of naphthalene and n-butene are produced,and converting them into high value-added products through alkylation has gained particular importance and interest.In this work,liquid coordination complexes(LCCs)were used as acid catalysts for the first time in the naphthalene alkylation reaction under mild conditions to obtain multibutylnaphthalenes with high yield.Various reaction conditions were thoroughly investigated.The LCC consisting of urea and AlCl_(3) showed excellent catalytic performance under optimal reaction conditions,giving 100%conversion of naphthalene and 99.66%selectivity towards multi-butylnaphthalenes.Combining the catalyst properties and catalytic results,a plausible reaction mechanism was proposed.The lubricating properties of the synthesized products were investigated for their potential application as lubricating base oils.The synthesized multi-butylnaphthalenes showed comparable physicochemical properties and tribological performances as the commercial cycloalkyl base oil. | Chen Chen Qiong Tang Hong Xu Lei Liu Mingxing Tang Xuekuan Li Jinxiang Dong | 2021 | Chinese Journal of Chemical Engineering2021，34，11： | 2 |
| 6 | A data affinity based garbage collector for multi-bank flash-memory storage system显示文摘 | Du Yehua Cai Ming Dong Jinxiang | | 0，，： | 1 |
| 7 | Synthesis and structure analysis of zeolite AS - 1 from HF - M2 03 - SiO2 - ethyl- enediamine - H20 显示文摘 | DONG JINXIANG WANG YINGXIA XU HONG | 2008 | Mieroporous and Mesoporous Materials2008，116，： | 1 |
| 8 | Ethylene glycol purification by melt crystallization:Removal of 2-methoxyethanol impurity显示文摘The coal(syngas)-to-ethylene glycol(CTEG),is contaminated with the naughty impurity 2-Methoxyethanol(ME)generated during the hydrogenation stage,which affect the quality of EG for fiber-grade polyester production.Distillation,is the employed separation process in industrial,which makes production complicated because of the heat sensitivity of the impurities system.Melt crystallization has been regarded as an effective technology to obtain high-purity organic compounds based on the melting points difference,which could avoid the problems by heating.In this work,we have explored the feasibility of the static melt crystallization on the separation of EG/ME in a jacketed crystallization tube.The experimental parameters were investigated,which covers crystallization and sweating stage in each step.The results showed that the purity of EG could reach≥99.8%from the binary system studied via the quaternary separation process. | Tiefeng Wang Jinxiang Dong | 2021 | Chinese Journal of Chemical Engineering2021，34，9： | 1 |
| 9 | Hydrolysis of δ- layered sodium disilicate in ions binding process显示文摘 | Jinxiang Dong Hong Xu Gaoyong Zhang | 2006 | Tenside Surfactants detergents2006，43，3： | 1 |
| 10 | Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study显示文摘 | HaiYing Chen Hui Yuan Rongbao Gao Jinxiang Zhang Dayan Wang Ying Xiong GuoYin Fan Fan Yang Xiaodan Li Jianfang Zhou Shumei Zou Lei Yang Tao Chen Libo Dong Hong Bo Xiang Zhao Ye Zhang Yu Lan Tian Bai Jie Dong Qun Li ShiWen Wang YanPing Zhang Hui Li Tian Go | 2014 | The Lancet2014，，： | 1 |
| 11 | Tribological and rheological performance of lithium grease with poly-a-olefin and alkyl-tetralin as base oils显示文摘A new category of lithium greases was synthesized by using poly-a-olefin(PAO8) and alkyl-tetralin as base oil, where the alkyl-tetralins were synthesized by the alkylation of tetralin and olefins. The influence of thickener concentration, alkyl-tetralin content and type of blend oils on the rheological and tribological performance of lithium grease was investigated. The microstructures of soap fibers were measured to reveal the structure-property correlations. The concentration of thickener and alkyl-tetralin content obviously affect the lubricating performance of lithium grease, while the molecular structure of alkyltetralin has no obvious impact on their properties. It was found that alkyl-tetralin could significantly enhance the thickening ability of PAO8 base oils, and decrease the amount of thickeners by 1.5%(mass).Lithium greases prepared using 20%(mass) alkyl-tetralin as co-base oil exhibited high colloidal stability,excellent rheological behaviors and tribological properties. | Chen Chen Yujie Liu Qiong Tang Hong Xu Mingxing Tang Xuekuan Li Lei Liu Jinxiang Dong | 2023 | Chinese Journal of Chemical Engineering2023，56，4： | 1 |
| 12 | Stability of layered sodium disilicate during hydration process as studied by multinuclear solid state NMR spectroscopy显示文摘 | Ai Xuanjun Deng Feng Dong Jinxiang | 2002 | J Phys Chem:B2002，106，36： | 1 |
| 13 | Interaction between Al -δ layered sodium disilicate and surfactant 显示文摘 | Jinxiang Dong Liping Li Hong Xu | 2007 | Journal of Surfactants and Detergents2007，10，1： | 1 |
| 14 | Variation of sodium coordination during the hydration processes of layered sodium disilicates as studied by 23Na MQMAS and1 H()23Na CP/MAS NMR spectroscopy显示文摘 | Ai Xuanjun Chen Lei Dong Jinxiang | 2003 | J Mater Chem2003，13，： | 1 |
| 15 | Conflicts classification and solving for collaborative feature modeling显示文摘 | Tang Min Chou Shangehing Dong Jinxiang | 2007 | Advanced Engineering Informatics2007，21，2： | 1 |
| 16 | Synthesis of Membranes of zeolites ZSM-5 and ZSM-35 by the Vapour Phase Method显示文摘 | Dong jinxiang Doutao Zhao Xingguo ct al | 1992 | Jes Chcm Commun1992，，15： | 1 |
| 17 | Solution-Mediated Transformation of a 1D [Zn(Im)(HIm)2(OAc)] Precursor to Several Different 3D Zn(Im)2 Frameworks显示文摘1D 化合物[Zn (Im )( 他)2(OAc)] 被用作金属和咪唑的一位单个先锋准备几 3-dimensional (3D ) 由调停答案的转变的 Zn (Im )2 框架。明确地,三已知的拓扑学, zni, coi 和 crb (BCT ) 与 CH 3 哦, DMF 和直接存储器存取作为溶剂分别地。由 13 C 妈 NMR 光谱学和 TG 从 1D 化合物在转变过程暗示那到coi-[ Zn ( Im ) 2](DMF) x 和crb-[ Zn ( Im ) 2](DMA) x ( ZIF-1 ), DMF 和直接存储器存取溶剂分子充当了指导结构的代理人并且因此,分别地在框架内被堵塞。相反,在 zni- 的形成[Zn (Im )2], 没有溶剂分子在框架是在场的;因此,到 zni 的从 1D 化合物的转变被温度导致。因此,一位单个先锋(1D 混合物) 的调停答案的转变途径为 ZIF 的合成被建立。 | Youjun Guan Qi Shi Jinxiang Dong | 2017 | Chinese Journal of Chemistry2017，35，7： | 1 |
| 18 | Variation of sodium coordination during the hydration processes of layered sodium disilicates as studied by 23Na MQMAS and 1H < 23Na CP/MAS NMR spectroscopy显示文摘 | AI XUANJUN CHEN LEI DONG JINXIANG | 2003 | Mater Chem2003，13，： | 1 |
| 19 | Stability of layered sodium disilicate during hydration process as studied by muhinuclear solid state NMR spectroscopy 显示文摘 | AI XUANJUN DENG FENG DONG JINXIANG | 2002 | Phys Chem (B)2002，106，： | 1 |
| 20 | Co-templating Ionothermal Synthesis and Crystal Structure of a New Layered Aluminophosphate from a Protic Deep Eutectic Solvent显示文摘Protic 深最容易溶解的混合物通常在特定的臼齿的比率由器官的胺 hydrochloride 盐和氢契约施主组成。此处,一个例子从基于脲的 protic 第一次被报导的 aluminophosphate 的 Ionothermal 合成最容易溶解的混合,由 diethylammonium 氯化物(DEACl ) 和 1,3-dimethyl 脲(DMU ) 组成。作为结果,一新有 4.8 网络的二维的 aluminophosphate,[CH 3 NH 3]2[(C2 H 5)2 NH 2]Al3(PO4)4, 被在 situ 的 DEA 和甲胺当 HF 不在时从 DMU 的分解产生了的模板 co 成功地综合了。把有更多的烷基组的盐与 N 原子连接了的第四级的铵比作烷基,这种器官的胺盐作为指导结构的代理人更可能综合在基于脲的深最容易溶解的混合物的 aluminophosphates。HF 对阶段选择关键,这也被发现,有像链的结构的已知的混合物面对 HF 作为一个指导结构的代理人与单个甲胺被获得。这些材料被粉末 XRD 描绘, SEM, TG-DSC, 13 C CP 妈 NMR 和 CHN 分析。 | Yuan Li Xiangdong Gong Lei Liu Jinxiang Dong | 2016 | Chinese Journal of Chemistry2016，34，4： | 1 |
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