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| 1 | Inhibitory effect of Jeju endemic seaweeds on the production of pro-inflammatory mediators in mouse macrophage cell line RAW 264.7显示文摘Seaweed has been used in traditional cosmetics and as a herbal medicine in treatments for cough,boils,goiters,stomach ailments,and urinary diseases,and for reducing the incidence of tumors,ulcers,and headaches.Despite the fact that seaweeds are frequently used in the practice of human health,little is known about the role of seaweed in the context of inflammation.This study aimed to investigate the influence of Jeju endemic seaweed on a mouse macrophage cell line(RAW 264.7) under the stimulation of lipopolysaccharide(LPS).Ethyl acetate extracts obtained from 14 different kinds of Jeju seaweeds were screened for inhibitory effects on pro-inflammatory mediators.Our results revealed that extracts from five seaweeds,Laurencia okamurae,Grateloupia elliptica,Sargassum thun-bergii,Gloiopeltis furcata,and Hizikia fusiformis,were potent inhibitors of the production of pro-inflammatory mediators such as nitric oxide(NO),prostaglandin E2(PGE2),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α).Based on these results,the anti-inflammatory effects and low cell toxicity of these seaweed extracts suggest potential thera-peutic applications in the regulation of the inflammatory response. | Eun-Jin YANG Ji-Young MOON Min-Jin KIM Dong Sam KIM Chan-Shick KIM Wook Jae LEE Nam Ho LEE Chang-Gu HYUN | 2010 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2010，11，5： | 5 |
| 2 | Significant risk and associated factors of active tuberculosis infection in Korean patients with inflammatory bowel disease using anti-TNF agents显示文摘AIM:To evaluate the incidence and risk factors of Korean tuberculosis(TB) infection in patients with inflammatory bowel disease(IBD) undergoing anti-TNF treatment.METHODS:The data of IBD patients treated with anti-TNFs in 13 tertiary referral hospitals located in the southeastern region of Korea were collected retrospectively.They failed to show response or were intolerant to conventional treatments,including steroids or immunomodulators.Screening measures for latent TB infection(LTBI)and the incidence and risk factors ofactive TB infection after treatment with anti-TNFs were identified.RESULTS:Overall,376 IBD patients treated with antiTNF agents were recruited(male 255,mean age of anti-TNF therapy 32.5±13.0 years);277 had Crohn’s disease,99 had ulcerative colitis,294 used infliximab,and 82 used adalimumab.Before anti-TNF treatment,screening tests for LTBI including an interferon gamma release assay or a tuberculin skin test were performed in 82.2%of patients.Thirty patients(8%)had LTBI.Sixteen cases of active TB infection including one TB-related mortality occurred during 801 personyears(PY)follow-up(1997.4 cases per 100000 PY)after anti-TNF treatment.LTBI(OR=5.76,95%CI:1.57-21.20,P=0.008)and WBC count<5000 mm3(OR=4.5,95%CI:1.51-13.44,P=0.007)during follow-up were identified as independently associated risk factors.CONCLUSION:Anti-TNFs significantly increase the risk of TB infection in Korean patients with IBD.The considerable burden of TB and marked immunosuppression might be attributed to this risk. | Eun Soo Kim Geun Am Song Kwang Bum Cho Kyung Sik Park Kyeong Ok Kim Byung Ik Jang Eun Young Kim Seong Woo Jeon Hyun Seok Lee Chang Heon Yang Yong Kook Lee Dong Wook Lee Sung Kook Kim Tae Oh Kim Jonghun Lee Hyung Wook Kim Sam Ryong Jee Seun Ja Park Hyun Jin Kim | 2015 | World Journal of Gastroenterology2015，21，11： | 5 |
| 3 | Effect of alloying elements and austenite destabilization heat treatment on graphitization of high chromiumcast iron 显示文摘 | Chang Sam Kyu Kim Dong Gyu and Choi | 1992 | International1992，32，11： | 1 |
| 4 | Long‐term incidence, risk factors, and management of biliary complications after adult living donor liver transplantation显示文摘 | Shin Hwang Sung‐Gyu Lee Kyu‐Bo Sung Kwang‐Min Park Ki‐Hun Kim Chul‐Soo Ahn Young‐Joo Lee Sung‐Koo Lee Gyu‐Sam Hwang Deok‐Bog Moon Tae‐Yong Ha Dong‐Sik Kim Jae‐Pil Jung Gi‐Won Song | 2006 | Liver Transpl2006，，5： | 1 |
| 5 | Non-lipid effects of rosuvastatin–fenofibrate combination therapy in high-risk Asian patients with mixed hyperlipidemia显示文摘 | Sang-Hak Lee Kyoung-Im Cho Jang-Young Kim Young Keun Ahn Seung-Woon Rha Yong-Jin Kim Yun-Seok Choi Si Wan Choi Dong Woon Jeon Pil-Ki Min Dong-Ju Choi Sang Hong Baek Kwon Sam Kim Young Sup Byun Yangsoo Jang | 2012 | Atherosclerosis2012，，： | 1 |
| 6 | Reconstruction of inferior right hepatic veins in living donor liver transplantation using right liver grafts显示文摘 | Shin Hwang Tae‐Yong Ha Chul‐Soo Ahn Deok‐Bog Moon Ki‐Hun Kim Gi‐Won Song Dong‐Hwan Jung Gil‐Chun Park Jung‐Man Namgoong Sung‐Won Jung Sam‐Youl Yoon Kyu‐Bo Sung Gi‐Young Ko Byungchul Cho Kyoung Won Kim Sung‐Gyu Lee | 2012 | Liver Transpl2012，，2： | 1 |
| 7 | Hemodynamics‐compliant reconstruction of the right hepatic vein for adult living donor liver transplantation with a right liver graft显示文摘 | Shin Hwang Tae‐Yong Ha Chul‐Soo Ahn Deok‐Bog Moon Gi‐Won Song Ki‐Hun Kim Dong‐Hwan Jung Gil‐Chun Park Kyu‐Bo Sung Gi‐Young Ko Kyoung Won Kim Byungchul Cho Jung‐Man Namgoong Sung‐Won Jung Sam‐Youl Yoon Chun‐Soo Park Yo‐Han Park Hyeong‐Woo Park Hyo‐Jun Lee | 2012 | Liver Transpl2012，，7： | 1 |
| 8 | Assessment of Ground Subsidence Hazard Near an Abandoned Underground Coal Mine Using GIS显示文摘 | Ki - Dong Kim Sam LeeHyun - Joo Oh Jong - Kuk Choi | 2006 | Environ Geo12006，，50： | 1 |
| 9 | Hyperoside prevents oxidative damage induced by hydrogen peroxide in lung fibroblast cells via an antioxidant effect显示文摘 | Mei Jing Piao Kyoung Ah Kang Rui Zhang Dong Ok Ko Zhi Hong Wang Ho Jin You Hee Sun Kim Ju Sun Kim Sam Sik Kang Jin Won Hyun | 2008 | BBA - General Subjects2008，，： | 1 |
| 10 | Usability of ringed polytetrafluoroethylene grafts for middle hepatic vein reconstruction during living donor liver transplantation显示文摘 | Shin Hwang Dong‐Hwan Jung Tae‐Yong Ha Chul‐Soo Ahn Deok‐Bog Moon Ki‐Hun Kim Gi‐Won Song Gil‐Chun Park Sung‐Won Jung Sam‐Youl Yoon Jung‐Man Namgoong Chun‐Soo Park Yo‐Han Park Hyeong‐Woo Park Hyo‐Jun Lee Sung‐Gyu Lee | 2012 | Liver Transpl2012，，8： | 1 |
| 11 | Modified right liver graft from a living donor to prevent congestion1显示文摘 | Sung Gyu Lee Kwang Min Park Shin Hwang Ki Hun Kim Dong Nak Choi Sun Hyung Joo Chul Soo Anh Yang Won Nah Jang Yeong Jeon Sang Hoon Park Kyung Suck Koh Sang Hoon Han Kyu Taek Choi Kyu Sam Hwang Yasuhiko Sugawara Masatoshi Makuuchi Pyung Chul Min | 2002 | Transplantation2002，，1： | 1 |
| 12 | Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice显示文摘 | Dong Hyun Kim Do Yoon Kim Young Choong Kim Ji Wook Jung Seungjoo Lee Byung Hoon Yoon Jae Hoon Cheong Yeong Shik Kim Sam Sik Kang Kwang Ho Ko Jong Hoon Ryu | 2007 | Life Sciences2007，，： | 1 |
| 13 | Effects of Alloying Elements Treatments on Graphitization and Austenite Destabilizalion of High Chromium Cast Iron 显示文摘 | Sam Kyu Chang Dong Gyu Kim Jin Won Choi | 1992 | ISIJ International1992，32，11： | 1 |
| 14 | A New Approach to Built-In Self-Testable Datapath Synthesis Based on Integer Linear Programming显示文摘 | Han Bin Kim Dong Sam Ha Takeshi Takahashi Takahiro J Yamaguchi | 2000 | IEEE transactions on very large scale integration systems2000，8，5： | 1 |
| 15 | Maximum allowable delay bounds of networked control systems 显示文摘 | DONG - Sung Kim Young Sam Lee Wook Hyun Kwon Hong Seong Park | 2003 | Control Engineering Practice2003，，11： | 1 |
| 16 | Maximum Allowable Delay Bounds of Networked Control Systems显示文摘 | Kim Dong Sung Lee Young Sam Kwon Wook Hyun etal | 2003 | Journal of Control Engineering Practice2003，，11： | 1 |
| 17 | Comparison of open lateral release and transarticular lateral release in distal chevron metatarsal osteotomy for hallux valgus correction显示文摘 | Ji Yong Ahn Ho Seong Lee Hannah Chun Jin Sam Kim Dong Kyo Seo Young Rak Choi Sang Woo Kim | 2013 | International Orthopaedics2013，，9： | 1 |
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