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17篇 您的检索式:作者名="Doucette T"
    题名 作者 年代 出处 被引量
1Investigating the technical, economic and environmental performance of electric vehicles in the real-world: A case study using electric scooters显示文摘JUSTIN D K DOUCETTE R T ROBINSON D 2011Journal of Power Sources2011,196,10:1
2Fear of falling and fall-related efficacy in relationship to functioning among community-living elders显示文摘TINETTI M E MENDES de LEON C F DOUCETTE J T 1994J Gerontol1994,49,3:1
3A comparison of high-speed flywheels,batteries,and ultracapacitors on the bases of cost and fuel economy as the energy storage system in a fuel cell based hybrid electric vehicle显示文摘Doucette R T McCulloch M D 0,,03:1
4Modeling the Prospects of Plug-in Hy-brid Electric Vehicles To Reduce COi Emissions显示文摘DoucetteR T McCulloch M D 2011Appl2011,2011,:1
5Is occult lymph node disease in colorectal cancer patients clinically significant?显示文摘Nicastri D G Doucette J T Godfrey T E 2007J Mol Diagn2007,9,5:1
6Mesenchymal stem ceils display tumor-specific tropism in an RCAS/Ntv-a glioma model 显示文摘Doucette T Rao G Yang Y 2011Neopla- sia2011,13,8:1
7Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model显示文摘Doucette T Rao G Yang Y 2011Neoplasia2011,13,8:1
8Modeling the CO2 emissions from battery electric vehicles given the power generation mixes of different countries显示文摘Doucette R T McCulloch M D 2011Energy Policy2011,39,2:1
9Mesenchymal stem cel s display tumor-specific tropism in an RCAS/Ntv-a glioma model显示文摘Doucette T Rao G Yang Y 0,,08:1
10The effect of the OS- HA lead exposure in construction standard on blood lead levels among iron workers employed in bridge rehabilitation 显示文摘LEVIN S M GOLDBERG M DOUCETTE J T 1997A JIM1997,31,3:1
11Assessing benthic impacts of organic enrichment from marine aquaculture 显示文摘HARGRAVE B T PHILLIPS G A DOUCETTE L I 1997Water Air and Soil Pollution1997,99,:1
12Entrepreneurial orientation as a basis for classification within a service industry: the case of retail pharmacy in- dustry显示文摘JAMBULINGAM T KATHURIA R DOUCETTE WR 2005Journal of Operations Management2005,23,:1
13Detailed measurements of velocities and suspended sand concentrations over full - scale ripple in regular oscillatory flow 显示文摘Van der Weft J j Doucette J S O' Donoghue T 2007Journal of Geophysics Research Earth Surface2007,112,2:1
14Modeling the prospects of plug-in hybrid electric vehicles to reduce CO 2 emissions显示文摘Doucette R T McCulloch M D 2011Applied Energy2011,88,7:1
15Modeling the CO2 emissions from battery electric vehicles given the power generation mixes of different countries显示文摘DOUCETTE R T MCCULLOCH M D 2011Energy Policy2011,39,1:1
16Modeling the prospects of plug-in hybrid electric vehicles to reduce CO2 emissions显示文摘Doucette R T McCulloch M D 2011Applied Energy2011,88,7:1
17Utility of the low-accelerating-dose regimen in 182 liver recipients with recurrent hepatitis C virus显示文摘AIM: To describe our experience using a low-acceleratingdose regimen(LADR) with pegylated interferon alpha-2a and ribavirin in treatment of hepatitis C virus(HCV) recurrence. METHODS: From 2003, a protocolized LADR strategy was employed to treat liver transplant(LT) recipients with recurrent HCV at our institution. Medical records of 182 adult patients with recurrent HCV treated with LADR between 1/2003 and 1/2011 were reviewed. Histopathology from all post-LT liver biopsies were reviewed in a blinded fashion. Paired recipient and donor IL28 B status were assessed. A novel technique was employed to ascertain recipient and donor IL28B(rs12979860) Gt data using DNA extracted from archival FFPE tissue from explanted native livers and donor gallbladders respectively. The primary endpoint was SVR; secondary endpoints examined include(1) patient and graft survival;(2) effect of anti-viral therapy on liver histology(fibrosis and inflammation);(3) incidence of on-treatment development of ACR, CDR, or PCH;(4) association of recipient and donor IL28 B genotype with SVR; and(5) incidence of antiviral therapy-associated adverse events(anemia, leukopenia, thrombocytopenia, depression) and hepatic decompensation.RESULTS: The overall SVR rate was 38%(29% Gt1, 67% Gt2, 86% Gt3 and 58% Gt4). HCV Gt(P < 0.0001), donor age(P = 0.003), cytomegalovirus mismatch(P = 0.001), baseline serum bilirubin(P = 0.002), and baseline viral load(P = 0.04) were independent predictors for SVR. SVR rates were significantly higher in the recipient-CC/donor-non CC pairs(P = 0.007). Neither baseline fibrosis nor change in fibrosis stage after anti-viral therapy were associated with SVR. Fibrosis progressed in 72% of patients despite SVR. Median graft survival was 91 mo. Five-year patient survival was superior in patients who achieved SVR(97% vs 82%, P = 0.001). Pre-treatment ALP ≥ 150 U/L(P = 0.01), total bilirubin ≥ 1.5 mg/d L(P = 0.001) and creatinine ≥ 2 mg/d L(P = 0.001) were independently associated with patient survival. Only 13% of patients achieving SVR died during the followup period. Treatment discontinuation and treatmentrelated mortality occurred in 35% and 2.2% of patients, respectively. EPO, G-CSF and blood transfusion were needed in 89%, 40% and 23% of patients, respectively. Overall hospitalization rate for treatment-related serious adverse events was 21%. Forty-six(25%) of the patients were deceased; among those who died, 25(54%) were due to liver-related complications, and 4 deaths(9%) occurred while receiving therapy(2 patients experienced hepatic decompensation and 2 sepsis). CONCLUSION: LADR strategy remains relevant in managing post-LT recurrent HCV where access to DAAs is limited. SVR is associated with improved survival, but fibrosis progression still occurs.Kieron BL Lim Hamid R Sima M Isabel Fiel Viktoriya Khaitova John T Doucette Maria Chernyiak Jawad Ahmad Nancy Bach Charissa Chang Priya Grewal Leona Kim-Schluger Lawrence Liu Joseph Odin Ponni Perumalswami Sander S Florman Thomas D Schiano 2015World Journal of Gastroenterology2015,21,20:0
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