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| 1 | Investigating the technical, economic and environmental performance of electric vehicles in the real-world: A case study using electric scooters显示文摘 | JUSTIN D K DOUCETTE R T ROBINSON D | 2011 | Journal of Power Sources2011,196,10: | 1 |
| 2 | Fear of falling and fall-related efficacy in relationship to functioning among community-living elders显示文摘 | TINETTI M E MENDES de LEON C F DOUCETTE J T | 1994 | J Gerontol1994,49,3: | 1 |
| 3 | A comparison of high-speed flywheels,batteries,and ultracapacitors on the bases of cost and fuel economy as the energy storage system in a fuel cell based hybrid electric vehicle显示文摘 | Doucette R T McCulloch M D | | 0,,03: | 1 |
| 4 | Modeling the Prospects of Plug-in Hy-brid Electric Vehicles To Reduce COi Emissions显示文摘 | DoucetteR T McCulloch M D | 2011 | Appl2011,2011,: | 1 |
| 5 | Is occult lymph node disease in colorectal cancer patients clinically significant?显示文摘 | Nicastri D G Doucette J T Godfrey T E | 2007 | J Mol Diagn2007,9,5: | 1 |
| 6 | Mesenchymal stem ceils display tumor-specific tropism in an RCAS/Ntv-a glioma model 显示文摘 | Doucette T Rao G Yang Y | 2011 | Neopla- sia2011,13,8: | 1 |
| 7 | Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model显示文摘 | Doucette T Rao G Yang Y | 2011 | Neoplasia2011,13,8: | 1 |
| 8 | Modeling the CO2 emissions from battery electric vehicles given the power generation mixes of different countries显示文摘 | Doucette R T McCulloch M D | 2011 | Energy Policy2011,39,2: | 1 |
| 9 | Mesenchymal stem cel s display tumor-specific tropism in an RCAS/Ntv-a glioma model显示文摘 | Doucette T Rao G Yang Y | | 0,,08: | 1 |
| 10 | The effect of the OS- HA lead exposure in construction standard on blood lead levels among iron workers employed in bridge rehabilitation 显示文摘 | LEVIN S M GOLDBERG M DOUCETTE J T | 1997 | A JIM1997,31,3: | 1 |
| 11 | Assessing benthic impacts of organic enrichment from marine aquaculture 显示文摘 | HARGRAVE B T PHILLIPS G A DOUCETTE L I | 1997 | Water Air and Soil Pollution1997,99,: | 1 |
| 12 | Entrepreneurial orientation as a basis for classification within a service industry: the case of retail pharmacy in- dustry显示文摘 | JAMBULINGAM T KATHURIA R DOUCETTE WR | 2005 | Journal of Operations Management2005,23,: | 1 |
| 13 | Detailed measurements of velocities and suspended sand concentrations over full - scale ripple in regular oscillatory flow 显示文摘 | Van der Weft J j Doucette J S O' Donoghue T | 2007 | Journal of Geophysics Research Earth Surface2007,112,2: | 1 |
| 14 | Modeling the prospects of plug-in hybrid electric vehicles to reduce CO 2 emissions显示文摘 | Doucette R T McCulloch M D | 2011 | Applied Energy2011,88,7: | 1 |
| 15 | Modeling the CO2 emissions from battery electric vehicles given the power generation mixes of different countries显示文摘 | DOUCETTE R T MCCULLOCH M D | 2011 | Energy Policy2011,39,1: | 1 |
| 16 | Modeling the prospects of plug-in hybrid electric vehicles to reduce CO2 emissions显示文摘 | Doucette R T McCulloch M D | 2011 | Applied Energy2011,88,7: | 1 |
| 17 | Utility of the low-accelerating-dose regimen in 182 liver recipients with recurrent hepatitis C virus显示文摘AIM: To describe our experience using a low-acceleratingdose regimen(LADR) with pegylated interferon alpha-2a and ribavirin in treatment of hepatitis C virus(HCV) recurrence. METHODS: From 2003, a protocolized LADR strategy was employed to treat liver transplant(LT) recipients with recurrent HCV at our institution. Medical records of 182 adult patients with recurrent HCV treated with LADR between 1/2003 and 1/2011 were reviewed. Histopathology from all post-LT liver biopsies were reviewed in a blinded fashion. Paired recipient and donor IL28 B status were assessed. A novel technique was employed to ascertain recipient and donor IL28B(rs12979860) Gt data using DNA extracted from archival FFPE tissue from explanted native livers and donor gallbladders respectively. The primary endpoint was SVR; secondary endpoints examined include(1) patient and graft survival;(2) effect of anti-viral therapy on liver histology(fibrosis and inflammation);(3) incidence of on-treatment development of ACR, CDR, or PCH;(4) association of recipient and donor IL28 B genotype with SVR; and(5) incidence of antiviral therapy-associated adverse events(anemia, leukopenia, thrombocytopenia, depression) and hepatic decompensation.RESULTS: The overall SVR rate was 38%(29% Gt1, 67% Gt2, 86% Gt3 and 58% Gt4). HCV Gt(P < 0.0001), donor age(P = 0.003), cytomegalovirus mismatch(P = 0.001), baseline serum bilirubin(P = 0.002), and baseline viral load(P = 0.04) were independent predictors for SVR. SVR rates were significantly higher in the recipient-CC/donor-non CC pairs(P = 0.007). Neither baseline fibrosis nor change in fibrosis stage after anti-viral therapy were associated with SVR. Fibrosis progressed in 72% of patients despite SVR. Median graft survival was 91 mo. Five-year patient survival was superior in patients who achieved SVR(97% vs 82%, P = 0.001). Pre-treatment ALP ≥ 150 U/L(P = 0.01), total bilirubin ≥ 1.5 mg/d L(P = 0.001) and creatinine ≥ 2 mg/d L(P = 0.001) were independently associated with patient survival. Only 13% of patients achieving SVR died during the followup period. Treatment discontinuation and treatmentrelated mortality occurred in 35% and 2.2% of patients, respectively. EPO, G-CSF and blood transfusion were needed in 89%, 40% and 23% of patients, respectively. Overall hospitalization rate for treatment-related serious adverse events was 21%. Forty-six(25%) of the patients were deceased; among those who died, 25(54%) were due to liver-related complications, and 4 deaths(9%) occurred while receiving therapy(2 patients experienced hepatic decompensation and 2 sepsis). CONCLUSION: LADR strategy remains relevant in managing post-LT recurrent HCV where access to DAAs is limited. SVR is associated with improved survival, but fibrosis progression still occurs. | Kieron BL Lim Hamid R Sima M Isabel Fiel Viktoriya Khaitova John T Doucette Maria Chernyiak Jawad Ahmad Nancy Bach Charissa Chang Priya Grewal Leona Kim-Schluger Lawrence Liu Joseph Odin Ponni Perumalswami Sander S Florman Thomas D Schiano | 2015 | World Journal of Gastroenterology2015,21,20: | 0 |