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| 1 | Phases equilibrated with long-period stacking ordered phases in the Mg-rich corner of the Mg-Y-Zn system显示文摘Phase equilibria involving the long-period stacking ordered phases including 14 H,18 R and 10 H in the Mg-rich corner of the Mg-Y-Zn system at 400 and 500℃ have been experimentally investigated by using X-ray diffraction(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM)and high-angle annular dark-field scanning transmission electron microscopy(HAADF-STEM).The coexistence of 14 H and 18 R as well as 18 R and 10 H was confirmed from atomic scales.The phases 14 H,18 R and 10 H were all stable phases from 400 to 500℃.The experimentally proved three-phase equilibrium of14 H,18 R and α-Mg instead of 14 H,18 R and Mg_(24)Y_(5) were presented in the modified isothermal sections.The latter three-phase equilibrium was reported in the available literature.The modified isothe rmal sections are conducive to guide the composition design to obtain the alloys with favorable microstructure constituents and mechanical properties. | Yongxin Ruan Changrong Li Yuping Ren Xiaopan Wu Schmid-Fetzer Cuiping Guo Zhenmin Du | 2021 | Journal of Materials Science & Technology2021，，9： | 3 |
| 2 | Metabolic engineering of Escherichia coli for the production of Lacto-N-neotetraose(LNnT)显示文摘Lacto-N-neotetraose(LNnT),one of the most important human milk oligosaccharides,can be used as infants’food addi-tives.Nowadays,extraction,chemical and biological synthesis were utilized to obtain LNnT,while these methods still face some problems such as low yield and high cost.The aim of current work is to construct a de novo biosynthesis pathway of LNnT in E.coli K12 MG1655.The lgtA and lgtB were first expressed by a plasmid,resulting in a LNnT titer of 0.04 g/L.To improve the yield of LNnT on substrate lactose,lacZ and lacI were knocked out,and lacY was over-expressed.As a result,the yield of LNnT on lactose increased from 0.01 to 0.09 mol/mol,and the titer of LNnT elevated to 0.41 g/L.In addition,the pathway was regulated using the titer of Lacto-N-triose II(LNTII)as a measure,and obtained a high titer strain of LNnT for 1.04 g/L.Finally,the gene expressions were fine-tuned,the titer of LNnT reached 1.2 g/L,which was 93%higher than the control strain,and the yield on lactose reached 0.28 mol/mol.The engineering strategy of pathway construction and modulation used in this study is applicable to facilitate the microbial production of other metabolites in E.coli. | Wei Zhang Zhenmin Liu Mengyue Gong Nan Li Xueqin Lv Xiaomin Dong Yanfeng Liu Jianghua Li Guocheng Du Long Liu | 2021 | Systems Microbiology and Biomanufacturing2021，1，3： | 2 |
| 3 | Thermodynamic modeling of the La-Mg-Y system and Mg-based alloys database显示文摘As an example of the La-Mg-Y system, the method how to set up the thermodynamic model of individual phases was introduced in the process of thermodynamic optimization. The solution phases (liquid, body-centered cubic, face-centered cubic, hexagonal close-packed and double hexagonal close-packed) were modeled with the Redlich-Kister equation. The compound energy model has been used to describe the thermodynamic functions of the intermetallic com- pounds in the La-Mg-Y systems. The compounds Mg2Y, Mg24Y5, Mg12La, Mg17La2, Mg41La5, Mg3La and Mg2La in the La-Mg-Y system were treated as the formulae (Mg,Y)2(La,Mg,Y), Mg24(La,Mg,Y)4Y, Mg12(La,Y), Mg17(La,Y)2, Mg41(La,Y)5, Mg3(La,Mg,Y) and Mg2(La,Y), respectively. A model (La,Mg,Y)0.5(La,Mg,Y)0.5 was applied to describe the compound MgM formed by MgLa and MgY in order to cope with the order-disorder transition between body-centered cu- bic solution (A2) and MgM with CsCl-type structure (B2) in the La-Mg-Y system. The Gibbs energies of individual phases were optimized in the La-Mg, La-Y and La-Mg-Y systems by CALPHAD technique. The projection of the liquidus sur- faces for the La-Mg-Y system was predicted. The Mg-based alloys database including 36 binary and 15 ternary systems formed by Mg, Al, Cu, Ni, Mn, Zn and rare earth elements was set up in SGTE standard. | DU Zhenmin GUO Cuiping LI Changrong ZHANG Weijing | 2006 | Rare Metals2006，25，5： | 2 |
| 4 | The Role of Ti in the Preparation of SiC/7075 Aluminum Matrix Composite显示文摘SiC/7075 aluminum matrix composites were prepared by a liquid stirring method.The role of Ti facilitating the preparation of SiC/7075 aluminum matrix were studied by means of direct-reading spectrometer,scanning electron microscope,energy dispersive spectrometer,X-ray diffraction and the sessile drop method.The results show that the SiC content in the SiC/7075 composite increases with an increase of Ti addition.The addition of Ti can significantly improve the wettability of SiC/Al system,there is a critical value of above 0.5%of Ti content in improving the wettability of the Al/SiC system at 1173K.The temperature of the'non wetting-wetting'transition for the(Al-2Ti)/SiC system is about 1123K,the contact angle decreases to 88°at 200 seconds and reaches a stable contact angle of 28°at 2100 seconds. | ZHANG Wenda CHEN Chengcheng XU Hong CHE Luchang GUO Cuiping DU Zhenmin | 2020 | Journal of Wuhan University of Technology(Materials Science)2020，35，2： | 2 |
| 5 | Effects of Sc content on the microstructure of As-Cast Al-7wt.% Si alloys显示文摘 | Wenda Zhang Yun Liu Jing Yang Jinzhi Dang Hong Xu Zhenmin Du | 2011 | Materials Characterization2011，，： | 1 |
| 6 | The thermodynamic re-assessment of the Cu–Zr system显示文摘 | Na Wang Changrong Li Zhenmin Du Fuming Wang Weijing Zhang | 2006 | Calphad2006，，4： | 1 |
| 7 | Thermodynamic modeling of the Ru - Zr system显示文摘 | Ran Hongtao Du Zhenmin Guo Cuiping | 2008 | Journal of Alloys and Compounds2008，464，： | 1 |
| 8 | Thermodynamic assessment of the La-Mg system 显示文摘 | Guo Cuiping Du Zhenmin | 2004 | Journal of Alloys and Compounds2004，385，： | 1 |
| 9 | Registration of intervention trials of Traditional Chinese Medicine for four neurological diseases on Chinese Clinical Trial Registry and Clinical Trials.gov:a narrative review显示文摘OBJECTIVE:To analyze the current status of clinical trial registration of Traditional Chinese Medicine(TCM)for the treatment of neurological diseases.METHODS:Interventional clinical trials of TCM treatment for ischemic stroke,hemorrhagic stroke,vascular cognitive impairment,tension-type headache before September 22,2020 on the platform of Chinese Clinical Trial Registry(Chi CTR),and Clinical Trials.gov were searched.Two researchers independently selected the literature and extracted data.RESULTS:A total of 180 interventional clinical trials were included for analysis.Out of 180 trials,127 were from Chi CTR and 53 from Clinical Trials.gov.The countries primary sponsoring the included trials were China(176,97.8%),and the common categories of primary sponsors were hospital(131,72.8%).Among the study design,the largest proportion of allocation was randomized(172,95.6%),interventional model assignment was parallel(163,90.6%),masking was double blind 49(27.2%),and the sample size was≤400(144,80.0%).The trials were most carried out at a single center(102,56.7%).Among the included studies,112(62.2%)registered on Chi CTR attached the ethical approval documents.In terms of trial stages,50(27.7%)studies were in phaseⅣ.The mostly used intervention was Chinese herbal medicines(99,55%),acupuncture(68,37.8%)was the second.By searching the registration number on China National Knowledge Infrastructure Database and Pub Med,38(21.1%)registered trials were published,including 25 protocol studies and 14 research results with one(NCT02275949)published both the protocol and the results.CONCLUSIONS:Irregular and inadequate reporting,untimely update and publication,insufficient information on traditional medicine unique characteristics,and lack of international collaborations are the problems existing in the interventional clinical registration trials of traditional medicine treatment on neurological diseases.More efforts need to be made from the above aspects to standardize and improve the registration of traditional medicine trials. | WEI Jingjing GUO Rongjuan FU Guojing LIANG Xiao XU Zhenmin JIA Min ZENG Zixiu DU Wanqing JIAO Weiwei SUN Linjuan LIU Hongmei GUO Chunli TONG Chenguang ZHANG Yunling LIAO Xing | 2022 | Journal of Traditional Chinese Medicine2022，42，1： | 1 |
| 10 | Thermodynamic assessment of the Bi-Mg binary system显示文摘The Bi-Mg binary system had been assessed by adopting the ionic melt and the modified quasi-chemical models to describe the liquid phase with short range ordering behavior. In general considerations of the development of the thermodynamic database of the multi-component Mg-based alloys and the consistency of the thermodynamic models of the related phases, the Gibbs energy descriptions of all the phases in the Bi-Mg binary system were reasonably re-modeled and critically re-assessed in the present work. Especially for the liquid phase, the associate model was used with the constituent species Bi, Mg and Bi2Mg3. The Mg-rich terminal phase hcp_A3 was modeled as a substitutional solution following Redlich-Kister equation and the Bi-rich terminal phase Rhombohedral_A7 was treated as a pure Bi substance since the extremely small solubility of Mg in Bi. The low and high temperature non- stoichiometric compounds β-Bi2Mg3 and α-Bi2Mg3 were described by the sublattice models (Bi,Va)2Mg3 and (Bi)1(Bi,Va)3Mg6 respectively based on their structure features. A set of self-consistent thermodynamic parameters of the Bi-Mg system was obtained and the experimental thermodynamic and phase equilibrium data were well reproduced by the optimized thermodynamic data. | Chunju NIU Changrong LI Zhenmin DU Yongjuan JING | 2012 | Acta Metallurgica Sinica(English Letters)2012，25，1： | 1 |
| 11 | Study on the interfacial reactions of Ti/AIN joints显示文摘基于在关节的不同类型之间的 Ti-Al-N 第三的系统,界面的反应和阶段形成序列的阶段平衡计算,( Ti 矩阵)/( AlN 粒子),( Ti 粒子)/( AlN 板),并且( Ti 板)/( AlN 板),在报导试验性的条件下面理论上被分析。为三种 Ti/AlN 关节的不同阶段形成序列被获得。它证明不同阶段两个定序阶段形成序列,明显的空间阶段序列被相对数量和二对的分发在散开夫妇统治。理论预言能解释试验性的观察很好。 | GAO Jie LI Changrong WANG Na DU Zhenmin | 2008 | Rare Metals2008，27，2： | 1 |
| 12 | Thermodynamic assessment of the Ti-B system显示文摘 | MA Xiaoyan LI Changyong DU Zhenmin | 2004 | J Alloy Compd2004，370，： | 1 |
| 13 | Identification of Cytochrome P450 (CYP) Genes in Zhikong Scallop (Chlamys farreri)显示文摘Cytochrome P450 (CYP) superfamily is one of the membership largest and function most diverse protein superfamily recogniozed among living beings. Members of this superfamily were further assigned to different families and subfamilies based on their amino acid similarities. According to their phylogenetic relationships, the CYP genes which likely diverged from common ancestor gene and may share common functions were grouped into one clan. Widely distributing scallops are a group of the most conspicuous bivalve; however the studies on their CYP is acarce. In this study, we searched the genome and expressed sequence tags of Zhikong scallop (Chlamys farreri) for CYP genes. In total, 88 non-redundant CYP were identified, which were homed in 13 CYPs gene families. Phylogenetic analysis divided these genes into 4 CYP clans. As in deuterostomes, Clan 2 was the largest, which contained 33 genes belonging to CYP1, CYP2, CYP17 and CYP356 families. Clan 3 contgained 19 genes belonging to CYP3, CYP5 and CYP30 families. Clan 4 contained 23 genes, all belonging to CYP4 family. The mitochondrial CYP clan contained 9 genes belonging to CYP10 and CYP24 families. In comparison, protostomes (C. farreri, D. pluex, D. melanogaster) contained more CYP genes than deuterostomes (S. purpuratus and vertebrates) in Clan 2 but less genes in Clan 3 and Clan 4. Our findings will aid to deciphering CYP function and evolution in scallops and bivalves. | GUO Huihui BAO Zhenmin DU Huixia ZHANG Lingling WANG Shi SUN Luyang MOU Xiaoyu HU Xiaoli | 2013 | Journal of Ocean University of China2013，12，1： | 0 |
| 14 | Thermodynamic re-assessment of the Mg-Gd-Y ternary system coupling with the driving forces for phase precipitations during aging process显示文摘Based on the available experimental phase equilibrium relations and aging precipitation sequences,the Mg–Gd–Y ternary system has been thermodynamically re-assessed by means of CALPHAD technique.To simulate the experimentally reported aging precipitation sequence,α(Mg)_(SS)(supersaturated)→GP zones(D019-type,metastable)→β’-Mg_(7)Gd(c-bco,metastable)→β_(1)-Mg_(3)Gd(fcc,metastable)→β-Mg_(5)Gd(fcc,stable)near the Mg–Gd side,andα(Mg)SS(supersaturated)→β’-Mg_(7)Y(c-bco,metastable)→β-Mg_(24)Y_(5)(bcc,stable)near the Mg–Y side,the effective nucleation driving forces obtained by deducting the nucleation resistances from the thermodynamic driving forces are calculated and analyzed.Two metastable components,GP zones(D019-type)andβ’(c-bco)ordered fromα(Mg)_(SS),do not exist in the stable equilibrium phase diagram but appear in the annealing process of typical alloys.The Redlich–Kister equations are adopted to describe three solution phases,Liquid,HCP_A3 and BCC_A2.The intermediate compounds Mg_(2)Y,Mg_(24)Y_(5),Mg_(2)Gd,Mg_(3)Gd and Mg_(5)Gd are expressed by the formulas of(Mg,Y)_(2/3)(Gd,Mg,Y)_(1/3),Mg_(24/29)(Gd,Mg,Y)_(4/29)Y1/29,(Gd,Mg)_(2/3)(Gd,Mg,Y)_(1/3),(Gd,Mg)_(3/4)(Gd,Mg,Y)_(1/4)and Mg_(5/6)(Gd,Mg,Y)_(1/6),respectively.In particular,the two-sublattice models(Gd,Mg,Y)_(1/2)(Gd,Mg,Y)_(1/2),(Gd,Mg,Y)_(3/4)(Gd,Mg,Y)_(1/4)and(Gd,Mg,Y)_(7/8)(Gd,Mg,Y)_(1/8)have been respectively used to describe the stable Mg(Gd,Y)(BCC_B2)alloy compound as well as the metastable GP zones(D019-type)andβ’(c-bco)phase,in order to cope with the order-disorder transitions.A set of self-consistent thermodynamic parameters has been obtained to ensure the thermodynamic calculations well consistent with the reported experimental data,containing not only the stable equilibrium phase diagram but also the aging precipitation sequence. | Xiaopan Wu Changrong Li Cuiping Guo Zhenmin Du | 2023 | Journal of Magnesium and Alloys2023，11，7： | 0 |
| 15 | Thermodynamic analysis of the Ti-Al-N system显示文摘Motivated by the application of (Ti, Al)N alloy compound in the coating layer, the ternary phase diagram of Ti-Al-N was analyzed by the calculation of the phase diagram (CALPHAD) technique. The isothermal sections of the Ti-Al-N ternary system were constructed and compared with the literature experimental results. The thermodynamic parameters of the Ti-Al-N ternary sys- tem and the related Ti-N and Al-N binary systems were adopted from literatures, whereas, those of the Ti-Al binary from the literatures were adjusted according to both the ternary and the binary phase equilibria. The consistency between the calculated results and the experimental data shows that considering the ternary thermodynamic relationship, the adjustments to the thermodynamic parameters of the related binaries are necessary. | Jie Gao Changrong Li Na Wang Zhenmin Du | 2008 | Journal of University of Science and Technology Beijing2008，15，4： | 0 |
| 16 | RESEARCH & DESIGN OF 60 kW SOFT-SWITCHING PLASMA CONVERTER显示文摘有由利用吸引的电感,漏电感和分布式的电感软开关的完整的范围的 A 小说 60 kW 血浆变换器被介绍。当前的注射转移阶段的技术成功地被介绍进软切换的血浆变换器的研究。变压器的磁性的偏爱和交换部分的保护被解决。测试声明电源供应有优秀特征和更高的效率并且能遇见大电源血浆过程的需求很好。 | DU Gulping HUANG Shisheng WANG Zhenmin ZENG Min CHEN Lijun | 2006 | Chinese Journal of Mechanical Engineering2006，19，1： | 0 |
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