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| 1 | Systematic review and meta-analysis of esophageal cancer in Africa:Epidemiology, risk factors, management and outcomes显示文摘BACKGROUND Esophageal cancer(EC)is associated with a poor prognosis,particularly so in Africa where an alarmingly high mortality to incidence ratio prevails for this disease.AIM To provide further understanding of EC in the context of the unique cultural and genetic diversity,and socio-economic challenges faced on the African continent.METHODS We performed a systematic review of studies from Africa to obtain data on epidemiology,risk factors,management and outcomes of EC.A non-systematic review was used to obtain incidence data from the International Agency for Research on Cancer,and the Cancer in Sub-Saharan reports.We searched EMBASE,PubMed,Web of Science,and Cochrane Central from inception to March 2019 and reviewed the list of articles retrieved.Random effects metaanalyses were used to assess heterogeneity between studies and to obtain odds ratio(OR)of the associations between EC and risk factors;and incidence rate ratios for EC between sexes with their respective 95%confidence intervals(CI).RESULTS The incidence of EC is higher in males than females,except in North Africa where it is similar for both sexes.The highest age-standardized rate is from Malawi(30.3 and 19.4 cases/year/100000 population for males and females,respectively)followed by Kenya(28.7 cases/year/100000 population for both sexes).The incidence of EC rises sharply after the age of 40 years and reaches a peak at 75 years old.Meta-analysis shows a strong association with tobacco(OR 3.15,95%CI:2.83-3.50).There was significant heterogeneity between studies on alcohol consumption(OR 2.28,95%CI:1.94-2.65)and on low socioeconomic status(OR 139,95%CI:1.25-1.54)as risk factors,but these could also contribute to increasing the incidence of EC.The best treatment outcomes were with esophagectomy with survival rates of 76.6%at 3 years,and chemo-radiotherapy with an overall combined survival time of 267.50 d.CONCLUSION Africa has high incidence and mortality rates of EC,with preventable and nonmodifiable risk factors.Men in this setting are at increased risk due to their higher prevalence of tobacco and alcohol consumption.Management requires a multidisciplinary approach,and survival is significantly improved in the setting of esophagectomy and chemoradiation therapy. | Akwi W Asombang Nathaniel Chishinga Alick Nkhoma Jackson Chipaila Bright Nsokolo Martha Manda-Mapalo Joao Filipe G Montiero Lewis Banda Kulwinder S Dua | 2019 | World Journal of Gastroenterology2019，25，31： | 9 |
| 2 | Cardiac adipose tissue and its relationship to diabetes mellitus and cardiovascular disease显示文摘Type-2 diabetes mellitus(T2DM) plays a central role in the development of cardiovascular disease(CVD). However, its relationship to epicardial adipose tissue(EAT) and pericardial adipose tissue(PAT) in particular is important in the pathophysiology of coronary artery disease. Owing to its close proximity to the heart and coronary vasculature, EAT exerts a direct metabolic impact by secreting proinflammatory adipokines and free fatty acids, which promote CVD locally. In this review, we have discussed the relationship between T2 DM and cardiac fat deposits, particularly EAT and PAT, which together exert a big impact on the cardiovascular health. | Adam M Noyes Kirandeep Dua Ramprakash Devadoss Lovely Chhabra | 2014 | World Journal of Diabetes2014，5，6： | 8 |
| 3 | Upper gastrointestinal tract involvement of pediatric inflammatory bowel disease: A pathological review显示文摘Upper gastrointestinal(UGI) tract involvement of inflammatory bowel disease(IBD) is commonly seen in pediatric patients. Upper endoscopy is included in the routine workup of children with suspected IBD to enhance the diagnosis and management of these patients. Currently, childhood IBD is classified into ulcerative colitis(UC), atypical UC, Crohn's disease(CD) and IBD unclassified.Histologic confirmation of UGI tract involvement, in particular the presence of epithelioid(non-caseating) granulomas, is helpful in confirming the diagnosis of IBD and its classification. Herein, we reviewed selected IBD-associated UGI tract manifestations in children. Lymphocytic esophagitis, seen predominantly in CD,is histologically characterized by increased intraepithelial lymphocytes(> 20 in one high-power field) in a background of mucosal injury with absence of granulocytes. Focally enhanced gastritis is a form of gastric inflammation in pediatric IBD marked by a focal lymphohistiocytic pit inflammation with or without granulocytes and plasma cells in a relatively normal background gastric mucosa. Duodenal inflammation seen in children with IBD includes cryptitis,villous flattening, increased intraepithelial lymphocytes, and lamina propria eosinophilia. Finally, epithelioid granulomas not associated with ruptured gland/crypt are a diagnostic feature of CD. The clinicopathologic correlation and differential diagnosis of each microscopic finding are discussed. Clinicians and pathologists should be cognizant of the utility and limitations of these histologic features. | Dua Abuquteish Juan Putra | 2019 | World Journal of Gastroenterology2019，25，16： | 5 |
| 4 | 精神病学与电影:从神奇的画面中我们可以学到什么?(英文)显示文摘概述:电影是一种社会形态的载体,它可展示精神疾病的各个不同方面。由于电影的戏剧性和污蔑性的描述,它有时会传播有关精神疾病的消极影响,给病人带来痛苦。与消极影响相比,虽然它也会有一些正面和鼓舞人心的故事,但却是少之又少。在此,我们将描述电影对精神病学的双重影响。 | Soumitra DAS Nimisha DOVAL Shabna MOHAMMED Neha DUA Seshadri Sekhar CHATTERJEE | 2017 | 上海精神医学2017，29，5： | 3 |
| 5 | Efficacy and safety of self-expandable metal stents for biliary decompression in patients receiving neoadjuvant therapy for pancreatic cancer: a prospective study显示文摘 | A. Aziz Aadam Douglas B. Evans Abdul Khan Young Oh Kulwinder Dua | 2012 | Gastrointestinal Endoscopy2012，，1： | 2 |
| 6 | Closed reduction and percutaneous pinning of displaced supracondylar fractures of humerus in children with delayed presentation显示文摘肱骨的客观 Supracondylar 破裂在小儿科的肘附近说明 60% 所有破裂,甚至在发达国家, 18% 病人在医院里经历外科 48 小时或更长的列在后面表示。管理指南还不为谁的这些病人是清楚的在场迟了。这未来的研究的目的是评估跟随关上的减小并且在损害以后介绍 12 个小时或更多的肱骨的广泛地代替的 supracondylar 破裂的经皮的卡住的临床、放射学、功能的结果。我们考察了关上的减小并且与代替的扩展的在 40 个病人的用穿过的 K 电线的经皮的卡住的功能、放射学的结果的方法在表示与超过 12 个小时的延期打肱骨(Gartland 类型 III ) 的 supracondylar 骨折。病人的平均年龄是 4.5 年,在表示的吝啬的延期是 17.55 个小时。结果关上了减小,经皮的卡住在 90% 病人是成功的。平均数在时期上面列在后面是 15 个月。Baumann 的角度在所有病人在未受影响的方面的 4 度以内被恢复。在有严重胀大的病人的一个小中间的切口的使用帮助了我们避免尺骨的神经损害。用弗林的标准, 38 个病人(95%) 有优秀结果。二个病人有温和肌炎,两个有差的结果。任何一个都没病人开发肘脉内翻足。结论关上了减小并且交叉在孩子肱骨的代替的 supracondylar 破裂卡住甚至与推迟的表示是一个安全、有效的方法。 | Aman Dua Krishna Kiran Eachempati Rajesh Malhotra Lalit Sharma Mallinath Gidaganti | 2011 | Chinese Journal of Traumatology2011，14，1： | 2 |
| 7 | Autograft Limbal transplantation in patients with unilateral Corneal Stem Cell deficiency显示文摘 | DUA HS AZUATALANCO A | 2000 | Br J Ophtalmol2000，，84： | 1 |
| 8 | Autologous limbal transplantation in patients with unilateral corneal stem cell deficiency显示文摘 | Dua H S Azuara-Blanco A | 2000 | Br J Ophthalmol2000，84，3： | 1 |
| 9 | The amniotic membrane in ophthalmology 显示文摘 | Dua HS Gomes JAP King A J | 2004 | Survey of Ophthalmology2004，49，1： | 1 |
| 10 | 查看详情显示文摘 | S R Surwade V Dua N Manohar | | 0，，5： | 1 |
| 11 | Infliximab in the treatment of refractory posterior uveitis显示文摘 | Joseph A Raj D Dua HS | 2003 | Ophthalmology2003，110，7： | 1 |
| 12 | Biotechnology and bioremediation: successes and limitation显示文摘 | Dua M Singh A Sethunathan | 2002 | Appl Microbiol Biotechnol2002，59，： | 1 |
| 13 | Carbon-supported Pd-Co bimetallic nanoparticles as electrocatalysts for the oxygen reduction reaction 显示文摘 | Wang W Zheng D Dua C | 2007 | Journal of Power Sources2007，167，： | 1 |
| 14 | limbal stem cell of the corneal epithelium显示文摘 | Dua HS Azuara BA | 2000 | Surv Ophtalmol2000，44，6： | 1 |
| 15 | The effect of ramping casting speed and casting temperature on temperature distribution and melt flow patterns in the sump of a DC cast billet显示文摘 | DUA Q ESKIN L D KATGERMAN G | 2005 | Materials Science and Engineering2005，，： | 1 |
| 16 | Effect of chromium on activities of hydrolytic enzymes in germinating pea seeds 显示文摘 | Dua A Sawhney S K | 1991 | Environal of Experimental Botany1991，31，： | 1 |
| 17 | Unexpected visual improvement with a pinhole in central retinal artery occlusion and cilioretinal artery sparing fovea显示文摘 | Maharajan VS Dua HS Scott R | 2002 | Eye(Lond)2002，16，： | 1 |
| 18 | Does previous varicose vein surgery al- ter deep vein thrombosis risk after lower limb arthroplasty 显示文摘 | Dua A Neiva S Sutherland A | 2012 | Orthop Surg2012，4，4： | 1 |
| 19 | Nonlinear Model-Based Process Operation under UncertaintyUsing Exact Parametric Programming显示文摘In the present work, two new, (multi-)parametric programming (mp-P)-inspired algorithms for the solutionof mixed-integer nonlinear programming (MINLP) problems are developed, with their main focus being onprocess synthesis problems. The algorithms are developed for the special case in which the nonlinearitiesarise because of logarithmic terms, with the first one being developed for the deterministic case, and thesecond for the parametric case (p-MINLP). The key idea is to formulate and solve the square system of thefirst-order Karush-Kuhn-Tucker (KKT) conditions in an analytical way, by treating the binary variables and/or uncertain parameters as symbolic parameters. To this effect, symbolic manipulation and solution tech-niques are employed. In order to demonstrate the applicability and validity of the proposed algorithms, twoprocess synthesis case studies are examined. The corresponding solutions are then validated using state-of-the-art numerical MINLP solvers. For p-MINLP, the solution is given by an optimal solution as an explicitfunction of the uncertain parameters. | Vassilis M. Charitopoulos Lazaros G. Papageorgiou Vivek Dua | 2017 | Engineering2017，3，2： | 1 |
| 20 | The explicit linear quadratic regulator for constrained systems显示文摘 | BEMPORAD A MORARI M DUA V | 2002 | Automatica2002，38，1： | 1 |
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