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111篇 您的检索式:作者名="Duffe K"
    题名 作者 年代 出处 被引量
1Chemical and pharmacological evaluation of Hypericum perforation extracts显示文摘KEY WORDS Hypericum perforation; High pressure liquid chromatography; serotonin uptake inhibitors; tree radicals; antioxidants; hyperforin; hypericin; quercetin; rutinABSTRACTAIM: To determine the concentrations of chemical characteristic to extracts of leaves and flowers of Hypericum perforatnm (St John’s wort) in a number of selected samples and, following chemical characterization, to investigate the effects of these extracts on several pharmacological properties including effects of the extracts on inhibition of 5-hydroxytryptamine (5-HT) uptake and on an-tioxidant properties. METHODS: The samples were analyzed for the presence of characteristic chemicals by high performance liquid chromatography (HPLC) directly coupled to ultraviolet wavelength absorbance and positive or negative mode electrospray mass spectrometric detection. The effects of extracts on 5-HT uptake were determined by quantifying 3H-5-HT incorporation into rat hip-pocampal prisms. Estimates of effects of extracts on free radicalB Duff SLOLEY Liana J URICHUK LING Lei GU Lie-Dong Ronald T COUTTS Peter K T PANG Jacqueline J SHAN 2000Acta Pharmacologica Sinica2000,21,12:2
2Increased amyloid-beta42 ( 43 ) in brains of mice expressing mutant presenilin 1 显示文摘Duff K Eckman C Zehr C 1996Nature1996,383,6602:1
3Age-related amy- loid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuro- nal loss显示文摘Takeuchi A Irizarry MC Duff K 2000Am J Pathol2000,157,1:1
4Late-Breaking Clinical Trial Abstracts 显示文摘Haskell W Berra K Clark A Christopherson D Duff S George J Klieman L Myll J 2003Circulation2003,108,32:1
5Modular reconfigurable robots in space applications 显示文摘YIM M ROUFAS K DUFF D 2003Autonomous Robots2003,14,23:1
6NSABP Breast Cancer Prevention Trial risk as ses- sment program, version 2 显示文摘Anderson SJ Ahnn S Duff K 1992NSABP Bio- statistical Center Technical Report1992,,:1
7Estimating Net Benefits of Recreation under Conditions of Excess Demand 显示文摘McConneU K E Duff Virginia A 1976Journal of Environmental Economics and Management1976,2,1:1
8The multifrontal solution of indefinite sparse symmetric linear-equations显示文摘Duff I S Reid J K 1983ACM Transaction on Mathematical Software1983,9,:1
9Age-related amyloid beta deposi- tion in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss显示文摘Takeuchi A Irizarry MC Duff K 2000Am J Pathol2000,157,1:1
10Linking Aβ and tau in late-onset Alzheimer's disease: a dual pathway hypothesis 显示文摘SMALL S A DUFF K 2008Neuron2008,60,4:1
11Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches显示文摘Tsai J Grutzendler J Duff K 2004Nat Neurosci2004,7,11:1
12Limitations of commonly used spectrophotometric assay methods for phosphoenolpyruvate carboxykinase activity in crude extracts of muscle显示文摘Duff D A Snell K 0,,01:1
13Limitations of commonly used spectrophotometric assay methods for phosphoenolpyruvate carboxykinase activity in crude extracts of muscle显示文摘Duff D A Snell K 0,,01:1
14Utility of the RBANS in detecting cognitive impairment associated with Alzheimer's disease: sensitivity, specificity, and positive and negative predictive powers显示文摘Duff K Humphreys Clark JD O'Bryant SE 2008Arch Clin Neuropsychol2008,23,5:1
15Modeling term structures of defaultable bonds显示文摘Duffe D Singleton K J 1999Review ofFinancial Studies1999,12,1:1
16Tetraspanin-5 (Tm4sf9) mRNA expression parallels neuronal maturation in the cerebellum of normal and L7En-2 transgenic mice显示文摘Juenger CH Holst MI Duffe K 2005Comp Neurol2005,483,3:1
17An analysis of ISAR image distortion based on the phase modulation effect显示文摘Wong S K Riseborough E Duff G 2006EURASIP Journal on Applied Signal Processing2006,,11:1
18The multifrontal solution of indefinite sparse symmetric linear equations显示文摘Duff I S Reid J K 1983ACM Trans on Mathematical Software1983,9,3:1
19Use of in vivo models to study the role of choles- terol in the etiology of Alzheimer's disease显示文摘Burns M Duff K 2003Neurochem Res2003,28,7:1
20Building leadership capacity through peer career coaching: a case study显示文摘Sabo K Duff M Purdy B 2008Nurs Leadersh (Tar Ont)2008,21,1:1
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